Taniguchi, Masami Sato, Atsuhiko Mita, Haruhisa
Published in
Frontiers in Allergy
Although there are many case reports of asthma exacerbations with intravenous corticosteroids, especially hydrocortisone succinate, in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD), the frequency and mechanism remain unclear. We hypothesized that N-ERD patients are potentially hypersensitive to succinates, especially s...
Santos, Alexandra F. Worm, Margitta Kurita, Shoko Wong, Tania Contato, Davide Pirillo, Elia Esteban, A. Esther Tassinari, Paolo Perna, Flavia Chinthrajah, R. Sharon
...
Published in
Frontiers in Allergy
Background Few studies have addressed how food allergy may impact differently on the daily lives of adults with food allergies and caregivers for food-allergic dependents.Objective To explore similarities and differences in life experiences and unmet needs between individuals caring for a child with food allergy and adults with food allergy world-w...
Anderson, Sandra D. Kippelen, Pascale
Published in
Frontiers in Allergy
Exercise induced bronchoconstriction (EIB) describes the transient narrowing of the airways that follows vigorous exercise. It commonly occurs in children and adults who have asthma and in elite athletes. The primary stimulus is proposed to be loss of water, by evaporation, from the airway surface due to conditioning inspired air. The mechanism, wh...
Girkin, Jason L. N. Sokulsky, Leon A. Starkey, Malcolm R. Hansbro, Philip M. Foster, Paul S. Collison, Adam M. Mattes, Joerg
Published in
Frontiers in Allergy
Introduction Eosinophilic esophagitis (EoE) is associated with allergen-driven inflammation of the esophagus and an upregulated Th2 cytokine signature. Recombinant interleukin (IL)-13 (rIL-13) administration to mice induces some of the hallmark features of EoE, including increased eotaxin expression and eosinophil recruitment. Inflammation in EoE h...
Sekerel, Bulent Enis Ilgun Gurel, Deniz Sahiner, Umit Murat Soyer, Ozge Kocaturk, Emek
Published in
Frontiers in Allergy
Urticaria is a common disease that can affect individuals of all age groups, with approximately one-quarter of the population experiencing it at least once in their lifetime. Lesions characterized by erythema and itchy hives can appear anywhere on the body. These can vary in size ranging from millimeters to centimeters, and typically clear within 2...
Seys, Sven F. Gorris, Senne Uyttebroek, Saartje Backaert, Wout Jorissen, Mark Schrijvers, Rik Daems, Rembert Loeckx, Dirk Van Gerven, Laura Hellings, Peter W.
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Published in
Frontiers in Allergy
Background The skin prick test (SPT) is the gold standard for identifying allergic sensitization in individuals suspected of having an inhalant allergy. Recently, it was demonstrated that SPT using a novel skin prick automated test (SPAT) device showed increased reproducibility and tolerability compared to the conventional SPT, among other benefits...
Hervé, Pierre-Louis Dioszeghy, Vincent Matthews, Katie Bee, Katharine J. Campbell, Dianne E. Sampson, Hugh A.
Published in
Frontiers in Allergy
Given the potent immunological properties of the skin, epicutaneous immunotherapy (EPIT) emerges as a promising treatment approach for inducing immune tolerance, particularly for food allergies. Targeting the highly immunocompetent, non-vascularized epidermis allows for the application of microgram amounts of allergen while significantly reducing t...
Barne, Monica
Published in
Frontiers in Allergy
Low- and middle-income countries (LMICs) contribute to a major proportion of asthma morbidity and mortality globally, even though the prevalence is higher in high income countries. Mortality due to asthma is avoidable and patients should be able to live a near normal life. There are factors that influence overall disease prevalence and poor health ...
Aguilera, Juan Ibarra-Mejia, Gabriel Johnson, Mary
Published in
Frontiers in Allergy
Bousquet, Jean Klimek, Ludger Kuhl, Hans-Christian Nguyen, Duc Tung Ramalingam, Rajesh Kumar Canonica, G. W. Berger, William E.
Published in
Frontiers in Allergy
Background Azelastine hydrochloride (AZE) is a selective, non-sedating H1 antagonist with anti-inflammatory and mast cell stabilizing properties, which can be used as an alternative to intranasal corticosteroids. The objective of this study was to evaluate the efficacy of the new formulation of 0.15% AZE compared to that of the placebo at a dosage ...
