Tsatsakis, Aristidis Petrakis, Demetrious Nikolouzakis, Taxiarchis Konstantinos Docea, Anca Oana Calina, Daniela Vinceti, Marco Goumenou, Marina Kostoff, Ronald N. Mamoulakis, Charalampos Aschner, Michael
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Published in
Food and Chemical Toxicology
• Developmental exposure to environmental factors can disrupt the immune system. • Long-term low-dose exposure to chemical mixtures is linked to imunodeficiency • Immunodeficiency contributes to chronic diseases and the current Covid-19 pandemics. • Environmental chemicals and microorganisms share similar molecular pathomechanisms (AhR pathway). • ...
Leitch, Alistair C. Abdelghany, Tarek M. Probert, Philip M. Dunn, Michael P. Meyer, Stephanie K. Palmer, Jeremy M. Cooke, Martin P. Blake, Lynsay I. Morse, Katie Rosenmai, Anna K.
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Published in
Food and Chemical Toxicology
• “Ionic liquids” defines a diverse range of chemicals proposed as green chemicals. • There are limited data in mammalian systems regarding their potential toxicity. • The ionic liquid M8OI has been found at high levels in the environment. • M8OI inhibits mitochondrial function and induces mammalian cell apoptosis. • M8OI is metabolised to a lipoic...
Ahmed, Salman Khan, Haroon Aschner, Michael Hasan, Muhammad Mohtasheemul Sherif T.S. Hassan
Published in
Food and Chemical Toxicology
Mishra, Abtar Behura, Assirbad Mawatwal, Shradha Kumar, Ashish Naik, Lincoln Mohanty, Subhashree Subhasmita Manna, Debraj Dokania, Puja Mishra, Amit Patra, Samir K.
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Published in
Food and Chemical Toxicology
Lectins are proteins with a high degree of stereospecificity to recognize various sugar structures and form reversible linkages upon interaction with glyco-conjugate complexes. These are abundantly found in plants, animals and many other species and are known to agglutinate various blood groups of erythrocytes. Further, due to the unique carbohydra...
Li, Maiquan Huang, Weisu Jie, Fan Wang, Mengmeng Zhong, Yongheng Chen, Qi Lu, Baiyi
Published in
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Various phytochemicals have been reported to protect against oxidative stress. However, the mechanism underlying has not been systematically evaluated, which limited their application in disease treatment. Nuclear factor erythroid 2-related factor 2 (Nrf2), a central transcription factor in oxidative stress response related to numerous diseases, is...
Mancuso, Cesare Santangelo, Rosaria
Published in
Food and Chemical Toxicology
• P. ginseng and P. quinquefolius have been extensively studied for their beneficial effects. • Compound K, produced by the intestinal deglycosylation of ginseng, is a metabolite with pharmacological effects. • Clinical studies unraveled the positive effects of ginseng on cognitive skills, fatigue and glucose metabolism. • Further clinical studies ...
Mounir Ouzir Khalid El Bairi Saaïd Amzazi
Published in
Food and Chemical Toxicology
Esma Yagdi Claudia Cerella Dicato, Mario Marc Diederich
Published in
Food and Chemical Toxicology
In vitro and in vivo studies reported the anti-cancer potential of organosulfur compounds (OSCs) as they trigger biological effects leading to cell cycle arrest with accumulation of cells in G2/M, alteration of the microtubular network, modulation of Bcl-2 family protein expression patterns and changes of the redox status. Despite these well-descri...
Ahmed, R G
Published in
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Because bisphenol A (BPA) has been detected in animals, the aim of this study was to investigate the possible effects of maternal BPA exposure on the fetal endocrine system (thyroid-adipokine axis). BPA (20 or 40 μg/kg body weight) was orally administered to pregnant rats from gestation day (GD) 1-20. In both treated groups, the dams and their fetu...
Antonios Papastergiadis Amr Fatouh Liesbeth Jacxsens Carl Lachat Kshitij Shrestha Jeff Daelman Patrick Kolsteren Herman Van Langenhove Bruno De Meulenaer
Published in
Food and Chemical Toxicology
