Publication search

Inflammation, immunity and potential target therapy of SARS-COV-2: A total scale analysis review

Published in Food and Chemical Toxicology

Coronavirus disease-19 (COVID-19) is a complex disease that causes illness ranging from mild to severe respiratory problems. It is caused by a novel coronavirus SARS-CoV-2 (Severe acute respiratory syndrome coronavirus-2) that is an enveloped positive-sense single-stranded RNA (+ssRNA) virus belongs to coronavirus CoV family. It has a fast-spreadin...

Glossary of phytoconstituents: Can these be repurposed against SARS CoV-2? A quick in silico screening of various phytoc...

Published in Food and Chemical Toxicology

Image 1

Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine r...

Published in Food and Chemical Toxicology

SARS-CoV-2 is the coronavirus that originated in Wuhan in December 2019 and has spread globally. Studies have shown that smokers are less likely to be diagnosed with or be hospitalized for COVID-19 but, once hospitalized, have higher odds for an adverse outcome. We have previously presented the potential interaction between SARS-CoV-2 Spike glycopr...

Immunotoxic role of organophosphates: An unseen risk escalating SARS-CoV-2 pathogenicity

Published in Food and Chemical Toxicology

Image 1

Corrigendum to “Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases” [...

Published in Food and Chemical Toxicology

Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 ph...

Published in Food and Chemical Toxicology

Image 1

Thrombosis and Haemostasis challenges in COVID-19 – Therapeutic perspectives of heparin and tissue-type plasminogen acti...

Published in Food and Chemical Toxicology

• Anticoagulant therapy is essential in decreasing fibrin deposition and microthrombus formation in the ARDS and in the treatment of pro-thrombotic complications. • Administration of tPA in ARDS patients could provide anti-inflammatory effects. • Heparin and tPA may be useful in these patients minimizing the risk for ARDS complications and/or reduc...

Promising phytochemicals of traditional Indian herbal steam inhalation therapy to combat COVID-19 – An in silico study

Published in Food and Chemical Toxicology

Image 1

Exploring the magic bullets to identify Achilles' heel in SARS-CoV-2: Delving deeper into the sea of possible therapeuti...

Published in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

The symptoms associated with Covid-19 caused by SARS-CoV-2 in severe conditions can cause multiple organ failure and fatality via a plethora of mechanisms, and it is essential to discover the efficacious and safe drug. For this, a successful strategy is to inhibit in different stages of the SARS-CoV-2 life cycle and host cell reactions. The current...

The under-reported role of toxic substance exposures in the COVID-19 pandemic.

Published in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Coronavirus disease 2019 (COVID-19) and previous pandemics have been viewed almost exclusively as virology problems, with toxicology problems mostly being ignored. This perspective is not supported by the evolution of COVID-19, where the impact of real-life exposures to multiple toxic stressors degrading the immune system is followed by the SARS-Co...