Yu, Ting Zheng, Enze Li, Yanping Li, Yuqi Xia, Jun Ding, Qiuying Hou, Zhengping Ruan, Xiong Z Zhao, Lei Chen, Yaxi
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Published in
Experimental cell research
Palmitic acid (PA)-induced hepatocyte apoptosis is critical for the progression of nonalcoholic fatty liver disease (NAFLD). Inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) is an intracellular Ca2+-release channel and is involved in PA-induced hepatocyte apoptosis. While the expression of IP3R1 is elevated in patients with NAFLD and in hepatoc...
Boniewska-Bernacka, Ewa Pańczyszyn, Anna Klinger, Marian
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Experimental cell research
Telomeres are repetitive nucleoprotein structures located at the ends of chromosomes. Reduction in the number of repetitions causes cell senescence. Cells with high proliferative potential age with each replication cycle. Post-mitotic cells (e.g. cardiovascular cells) have a different aging mechanism. During the aging of cardiovascular system cells...
Zhu, Ming-Xia Wan, Wen-Li Hong, Yun Wang, Yan-Fang Dong, Fei Jing, Hong-Mei
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Experimental cell research
Mantle cell lymphoma (MCL) is a unique subtype of B-cell non-Hodgkin lymphoma with a generally aggressive and heterogeneous clinical course. Chemokines are one of the complex components in the tumor microenvironment (TME), and they play a vital role in tumor progression and metastasis. There is no information about the monokine induced by gamma int...
Ozeki, Nobuaki Mogi, Makio Hase, Naoko Hiyama, Taiki Yamaguchi, Hideyuki Kawai, Rie Matsumoto, Toru Nakata, Kazuhiko
Published in
Experimental cell research
Ozeki, Nobuaki Mogi, Makio Hase, Naoko Hiyama, Taiki Yamaguchi, Hideyuki Kawai, Rie Kondo, Ayami Matsumoto, Toru Nakata, Kazuhiko
Published in
Experimental cell research
Ozeki, Nobuaki Hase, Naoko Hiyama, Taiki Yamaguchi, Hideyuki Kawai-Asano, Rie Nakata, Kazuhiko Mogi, Makio
Published in
Experimental cell research
Ozeki, Nobuaki Hase, Naoko Kawai, Rie Yamaguchi, Hideyuki Hiyama, Taiki Kondo, Ayami Nakata, Kazuhiko Mogi, Makio
Published in
Experimental cell research
Ozeki, Nobuaki Kawai, Rie Yamaguchi, Hideyuki Hiyama, Taiki Kinoshita, Katsue Hase, Naoko Nakata, Kazuhiko Kondo, Ayami Mogi, Makio Nakamura, Hiroshi
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Published in
Experimental cell research
Zheng, Hongtu Yu, Shan Zhu, Congcong Guo, Tianan Liu, Fangqi Xu, Ye
Published in
Experimental cell research
Chemoresistance is a tremendous challenge to efficacy of systemic chemotherapy which is the preferred treatment for the advanced CRC patients. More tumor-associated macrophages (TAMs) are recruited into the CRC tumor under chemotherapy, which are highly implicated in the chemoresistance development, but the underlying molecular mechanism is unclear...
Suzuki, Kensuke Iwai, Hiroshi Utsunomiya, Keita Kono, Yumiko Kobayashi, Yoshiki Van Bui, Dan Sawada, Shunsuke Yun, Yasutaka Mitani, Akitoshi Kondo, Naoyuki
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Published in
Experimental cell research
Although surgical treatment cures >90% of differentiated thyroid cancer (DTC) patients, the remaining patients, including advanced DTC cases, have poor clinical outcomes. These patients with inoperable disease have only two choices of radioactive iodine therapy and tyrosine kinase inhibitors such as lenvatinib, which have a high incidence of treatm...
