Pacu, Irina Zygouropoulos, Nikolaos Furau, Cristian George Navolan, Dan Tit, Delia Mirela Ionescu, Cringu A. Stoian, Anca Pantea Petca, Aida Dimitriu, Mihai
Published in
Experimental and Therapeutic Medicine
This review provides a brief clinically relevant review of pheochromocytoma in pregnancy, to raise awareness among doctors in obstetrics and the aim is to serve as the first point of reference when confronted by their presence. Pheochromocytomas are neuroendocrine, catecholamine-secreting tumours. Despite having the highest incidence rate among oth...
Grad, Cosmin Pop, Andrei Gaborean, Emil Grad, Simona Dumitrascu, Dan
Published in
Experimental and Therapeutic Medicine
Analysis of serum biomarkers for the assessment of atrophic gastritis (AG), considered as precursor of the intestinal type of gastric cancer, is of growing interest. The combination of pepsinogen (PG), gastrin-17 (G17) and anti- Helicobacter pylori ( H. pylori ) antibody serological assays (panel test) is a non-invasive tool for the diagnosis of at...
Zhou, Xin Li, Shaojie Ma, Tiexiang Zeng, Jian Li, Huanyu Liu, Xiang Li, Feng Jiang, Bin Zhao, Ming Liu, Zhuo
...
Published in
Experimental and Therapeutic Medicine
Colorectal cancer (CRC) is a malignant tumor of the gastrointestinal tract and a leading cause of cancer-associated mortality worldwide. Mex-3 RNA binding family member A (MEX3A) promotes the progression of multiple types of cancer, including ovarian and cervical cancer. However, to the best of our knowledge, the role of MEX3A in CRC is not complet...
Binișor, Ioana Baniță, Ileana Monica Alexandru, Dragoș Mehedinți, Mihaela Cezarina Jurja, Sanda Andrei, Ana-Marina Pisoschi, Cătălina Gabriela
Published in
Experimental and Therapeutic Medicine
The connection between central obesity and the development and metastasis of various visceral tumors is largely accepted and one of the main causes seems to be the local synthesis of proangiogenic molecules. Progranulin (PRG), recently identified as an adipokine, is a novel pleiotropic growth factor acting on the proliferation and development of fa...
Badescu, Minerva Codruta Ciocoiu, Manuela Badulescu, Oana Viola Vladeanu, Maria-Cristina Bojan, Iris Bararu Vlad, Cristiana Elena Rezus, Ciprian
Published in
Experimental and Therapeutic Medicine
Venous thromboembolism (VTE) is a major healthcare problem due to its high incidence, significant mortality rate from pulmonary embolism, high recurrence rate and morbidity from long-term complications. After a first episode of VTE all patients must receive anticoagulant treatment for 3 months. Further anticoagulation is recommended in patients wit...
Zhu, Dongsheng Xu, Xiangfei Zhang, Ming Wang, Tong
Published in
Experimental and Therapeutic Medicine
The present study aimed to explore the prognostic value and role of kinesin family member 4A (KIF4A) expression in human osteosarcoma. KIF4A expression was evaluated in human osteosarcoma tissues from The Cancer Genome Atlas and Gene Expression Omnibus datasets. Reverse transcription-quantitative PCR was then applied to assess KIF4A level in both o...
Liang, Luqun Li, Shuang Liu, Huiming Mao, Yanwen Liu, Lingling Zhang, Xiaohuan Peng, Wei Xiao, Ying Zhang, Fan Shi, Mingjun
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Published in
Experimental and Therapeutic Medicine
Ski-related novel protein N (SnoN) negatively regulates the transforming growth factor-β1 (TGF-β1)/Smads signaling pathway and is present at a low level during diabetic nephropathy (DN), but its underlying regulatory mechanism is currently unknown. The present study aimed to assess the effects of insulin-controlled blood glucose on renal SnoN expre...
Xu, Xiabing Zhao, Yadong Duan, Gang Du, Bo
Published in
Experimental and Therapeutic Medicine
Long non-coding RNAs (lncRNAs) can function as onco-lncRNAs in several types of human cancer, including retinoblastoma (Rb). The present study investigated the potential role and regulatory mechanism of the lncRNA myocardial infarction-associated transcript (MIAT) in Rb. To do so, the expression levels of MIAT, microRNA (miR)-665, and LIM and SH3 p...
Yu, Huaixi Li, Yunyun Tang, Jinshan Lu, Xiaoqing Hu, Wen Cheng, Liang
Published in
Experimental and Therapeutic Medicine
The objective of the present study was to determine the role of RP11-84C13.1 in osteoporosis (OP) and its molecular mechanism. First, clinical samples were collected from OP patients and normal control patients. Human bone marrow stromal cells (hBMSCs) were extracted from femoral head tissues. Runt-related transcription factor 2 (RUNX2) and RP11-84...
Sandru, Florica Dumitrascu, Mihai Cristian Petca, Aida Carsote, Mara Petca, Razvan-Cosmin Oproiu, Ana Maria Ghemigian, Adina
Published in
Experimental and Therapeutic Medicine
Ganglioneuroma, a rare neural crest-derived tumor, exhibits a benign profile in contrast to other neuroblastic tumors (neuroblastoma/ganglioneuroblastoma). Ganglioneuromas can be found anywhere autonomic ganglia are located, mostly abdominal/pelvic sites followed by the adrenal glands (one-third of cases), mediastinum/thorax and cervical area. Affe...
