Sanchez‑Dominguez, Celia Hugo Leonid Gallardo Blanco Salinas‑Santander, Mauricio Ortiz‑Lopez, Rocio
Published in
Experimental and Therapeutic Medicine
Biotransformation is an enzyme‑catalyzed process in which the body converts endogenous compounds, xenobiotics and toxic substances into harmless or easily excreted metabolites. The biotransformation reactions are classified as phase I and II reactions. Uridine 5'‑diphospho (UDP)‑glucuronosyltransferases (UGTs) are a superfamily of phase II enzymes ...
VILLARREAL-MARTÍNEZ, ALEJANDRA Hugo Leonid Gallardo Blanco CERDA-FLORES, RICARDO TORRES-MUÑOZ, IRIS GÓMEZ-FLORES, MINERVA SALAS-ALANÍS, JULIO OCAMPO-CANDIANI, JORGE MARTÍNEZ-GARZA, LAURA
Published in
Experimental and Therapeutic Medicine
Psoriasis is a complex genetic disease, which has previously been associated with numerous single nucleotide polymorphisms (SNPs) that are implicated in various processes, including skin barrier functions and in the regulation of inflammatory and immune responses. The present study aimed to investigate the genotypic and allelic frequencies of 32 SN...
CONTRERAS-CAPETILLO, SILVINA NOEMI Hugo Leonid Gallardo Blanco CERDA-FLORES, RICARDO MARTIN LUGO-TRAMPE, JOSÉ TORRES-MUÑOZ, IRIS BRAVO-ORO, ANTONIO ESMER, CARMEN DE VILLARREAL, LAURA ELLA MARTÍNEZ
Published in
Experimental and Therapeutic Medicine
Individuals who suffer from spinal muscular atrophy (SMA) exhibit progressive muscle weakness that frequently results in mortality in the most severe forms of the disease. In 98% of cases, there is a homozygous deletion of the survival of motor neuron 1 (SMN1) gene, and both parents carry the same heterozygous genetic abnormality in the majority of...
Published in
Experimental and Therapeutic Medicine
The aim of this study was to investigate the clinical efficacy of free dermatoplasty combined with vacuum sealing drainage (VSD) for the treatment of large-area soft tissue defects accompanied by bone exposure in the lower leg (crus). Free dermatoplasty combined with VSD was used to treat 36 patients with large-area soft tissue defects accompanied ...
