Familiarity and Experience with Adverse Childhood Experiences Among Danish and University of Michigan Urologists.
Published in European urology
Technical Refinements in Superextended Robot-assisted Radical Prostatectomy for Locally Advanced Prostate Cancer Patient...
...Published in European urology
The feasibility and efficacy of robot-assisted radical prostatectomy (RARP) in locally advanced prostate cancer (PCa) patients with iT3 lesion at magnetic resonance imaging (MRI) are currently not explored. To describe our revised RARP technique (ie, superextended RARP [SE-RARP]) for PCa patients with posterior iT3a or iT3b at MRI. Data from 89 pat...
Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin.
Published in European urology
Our understanding of the mechanism of bacillus Calmette-Guérin (BCG) in controlling urothelial carcinoma is still evolving. Studies have revealed a complex and multifaceted immune response. BCG-elicited adaptive antitumor immunity directed towards tumor antigens could have major implications for trial design. Copyright © 2020 European Association o...
Re: Five-factor Prognostic Model for Survival of Post-platinum Patients with Metastatic Urothelial Carcinoma Receiving P...
Published in European urology
Transperineal interstitial laser ablation of the prostate, a novel option for minimally invasive treatment of benign pro...
Published in European urology
In the algorithm of treatment of benign prostatic obstruction (BPO), the shift from medical therapy to surgery is steep in terms of invasiveness. Recently, a lively interest has developed on alternative micro-invasive options. Transperineal interstitial laser ablation (TPLA) was recently proposed for BPO treatment. This work aims to illustrate feas...
The Predictive Value of Programmed Death Ligand 1 in Patients with Metastatic Renal Cell Carcinoma Treated with Immune-c...
...Published in European urology
Immune-checkpoint inhibitors (ICIs) are a mainstay treatment of metastatic renal cell carcinoma (mRCC). As not all patients benefit from ICIs, a biomarker-driven clinical decision-making strategy is desirable. To assess the predictive value of programmed death ligand 1 (PD-L1) in mRCC patients treated with ICIs. Multiple databases were searched for...
Taxane-induced Attenuation of the CXCR2/BCL-2 Axis Sensitizes Prostate Cancer to Platinum-based Treatment.
...Published in European urology
Taxanes are the most active chemotherapy agents in metastatic castration-resistant prostate cancer (mCRPC) patients; yet, resistance occurs almost invariably, representing an important clinical challenge. Taxane-platinum combinations have shown clinical benefit in a subset of patients, but the mechanistic basis and biomarkers remain elusive. To ide...
Continent Cutaneous Catheterizable Channels in Pediatric Patients: A Decade of Experience with Open and Robotic Approach...
Published in European urology
To allow patients with bladder and bowel dysfunctions to achieve social continence, continent catheterizable channels (CCCs) are effective alternatives to intermittent self-catheterization and enema. We aimed to describe our progressive advancement from open to robotic construction of CCCs, reporting outcomes and comparing the two approaches. We re...
The 2019 International Society of Urological Pathology Consensus Conference on Prostate Cancer Grading.
Published in European urology
Modifications recommended by the International Society of Urological Pathology 2019 conference on prostate cancer grading include the mandatory reporting of cribriform pattern and intraductal carcinoma, inclusion of intraductal carcinoma grade in the Gleason score, and separate aggregate reporting for magnetic resonance imaging-targeted lesions. Co...
Is it Time to Consider Eliminating Surgery from the Treatment of Locally Advanced Bladder Cancer?
Published in European urology
The similar clinical behavior, overlapping therapeutic patterns, and several clinical trials addressing the neoadjuvant and first-line therapy settings for bladder cancer support the call for a more uniform definition of "locally advanced" disease. We highlight the diverse therapeutic opportunities that patients with locally advanced bladder cancer...
