Gu, Jing Gupta, Rupal N Cheng, Henry K Xu, Yingxin Raal, Frederick J
Published in
European journal of preventive cardiology
Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disorder that results in elevated cholesterol levels, which can cause premature cardiovascular events such as heart attacks and stroke. We performed a literature review to systematically identify and analyse studies reporting on newer treatments for HoFH which lower cholesterol leve...
Gargiulo, Paola Basile, Christian Galasso, Gennaro Bellino, Michele D'Elia, Debora Patti, Giuseppe Bosco, Manuel Prinetti, Matteo Andò, Giuseppe Campanella, Francesca
...
Published in
European journal of preventive cardiology
This study, from the AT-TARGET-IT registry, investigates the effects of PCSK9i started at time of ACS hospitalization on lipid control and major CV events in the real world.Intensive and early PCSK9i therapy reduces composite major cardiovascular (CV) events in patients reaching LDL-C target values.A strike early–strike strong strategy is safe and ...
Palatini, Paolo
Published in
European journal of preventive cardiology
Bouchard, Karen Coutinho, Thais Tulloch, Heather
Published in
European journal of preventive cardiology
Çamlı, Ezgi Babayigit, Erdi Görenek, Bülent
Published in
European journal of preventive cardiology
Wan, Zhengwei Zhao, Jianhui Ye, Yongju Sun, Zhaochen Li, Kangning Chen, Yan Fang, Yuan Zhang, Yixuan Lin, Jiali Sun, Ping
...
Published in
European journal of preventive cardiology
Studies have reported that cardiovascular disease (CVD) is the leading cause of mortality for women. Meanwhile, women with polycystic ovary syndrome (PCOS) substantially elevate the risk of CVD. However, no studies have quantified the impact of PCOS on the overall CVD burden. This study performed a meta-analysis to assess the risk of CVD in an all-...
Marchandot, Benjamin Faller, Emilie Akladios, Cherif Matsushita, Kensuke Bäck, Magnus Jesel, Laurence Schini-Kerth, Valérie Morel, Olivier
Published in
European journal of preventive cardiology
Recently, a growing body of evidence has highlighted a concerning link between endometriosis and cardiovascular disease. Endometriosis, a chronic, inflammatory, hormone-dependent condition affecting 5-10% of reproductive-aged women worldwide, has long been associated with reproductive and gynaecological consequences. However, emerging research has ...
Nordeidet, Ada N Klevjer, Marie Øvretveit, Karsten Madssen, Erik Wisløff, Ulrik Brumpton, Ben M Bye, Anja
Published in
European journal of preventive cardiology
We conducted a genome-wide meta-analysis on resting heart rate (RHR), created a polygenic risk score for RHR, and examined the associations to cardiovascular disease outcomes.Sex-specific analyses indicated differences in the genetic contribution to RHR between men and women.High genetically predicted RHR was associated with increased risk of dilat...
Xie, Yao Zhu, Shiyu Wu, Shuang Liu, Chang Shen, Jian Jin, Chunna Ma, Hong Xiang, Meixiang
Published in
European journal of preventive cardiology
In the general population with insomnia, we uncovered the heterogeneous associations between different categories of hypnotics and incident cardiovascular events incorporating results from a propensity score matched cohort study of UK Biobank participants and drug-target Mendelian randomization analyses.Benzodiazepine was significantly associated w...
Nguyen, Tri-Long Trompet, Stella Brodersen, John B Hoogland, Jeroen Debray, Thomas P A Sattar, Naveed Jukema, J Wouter Westendorp, Rudi G J
Published in
European journal of preventive cardiology
This study investigates whether an algorithm to predict how much old age individuals would benefit from a statin treatment could be useful to guide clinicians in their prescription decision-making; the key findings are as follows:About one out of seven individuals included in the study has no predicted benefit of pravastatin.Compared with prescribi...
