Published in Equine veterinary journal
Peripheral caries (PC) has recently been shown to affect over half of UK and Australian horses. To examine affected cheek teeth histologically and ultrastructurally, to assess the possible route(s) of carious infection into the dental tissues and to further describe the pathological changes in affected teeth. Descriptive pathological study. Four co...
Published in Equine veterinary journal
Epiglottic entrapment can occur in yearling Thoroughbreds (TB); however, race performance following surgical correction is unknown. To determine the race performance of horses treated surgically for epiglottic entrapment as yearlings as compared to an untreated cohort. A second objective was to identify risk factors for treated horses not racing po...
Published in Equine veterinary journal
Allogeneic bone marrow-derived mesenchymal stem cells (BMDMSCs) could provide multiple advantages over autologous BMDMSCs, including creating an 'off-the-shelf' treatment together with the ability to control for donor variation. The objective of the study was to compare the clinical and synovial fluid response of the normal equine joint to autologo...
Published in Equine veterinary journal
Infection and dehiscence of simple lacerations is common in horses, and consistently effective methods of prevention are yet to be found. Honey has been shown to promote wound healing when applied topically; however, intralesional application prior to wound closure has not been reported. To examine whether intralesional application of medical grade...
Published in Equine veterinary journal
Belgian horses are commonly affected with ocular squamous cell carcinoma (SCC), the most common cancer of the equine eye. A missense mutation in damage-specific DNA binding protein 2 (DDB2 c.1013C>T, p.Thr338Met) has been established as a recessive genetic risk factor for ocular SCC in the Haflinger breed. A sample of Belgian horses with unknown SC...
Published in Equine veterinary journal
Synovial sepsis of unknown origin is a rare cause of lameness in the adult horse, and a haematogenous pathogenesis has been proposed in previous cases. To describe the features and outcome of synovial sepsis of unknown origin in adult Thoroughbred racehorses. Retrospective case series. Hospital records for admissions between 2005 and 2015 were revi...
Published in Equine veterinary journal
Primary hyperparathyroidism is uncommon in equids. To describe the diagnostic findings and efficacy of treatment in equids with primary hyperparathyroidism. Retrospective case series describing 16 horses and one mule. Cases were identified by retrospective review of records at Cornell University and via an ACVIM listserv query. Inclusion criteria w...
Published in Equine veterinary journal
Reliable and validated biomarkers for osteoarthritis (OA) are currently lacking. To develop an accurate and minimally invasive method to assess OA-affected horses and provide potential spectral markers indicative of disease. Observational, cross-sectional study. Our cohort consisted of 15 horses with OA and 48 without clinical signs of the disease,...
Published in Equine veterinary journal
Although, peripheral caries (PC) affects almost half of UK horses, no comprehensive microbiological study has been performed on this disorder. As a high proportion of oral bacteria cannot be conventionally cultured, molecular microbiological techniques such as Next Generation Sequencing are required to examine the complex oral bacteria community. T...
Published in Equine veterinary journal
The hyperglycaemic clamp has been used for measurement of insulin sensitivity (IS) but not for measurement of β-cell response in the horse. However, the repeatability of this test has not been reported for horses. To determine the repeatability and reliability of measures for IS and β-cell response to glucose using the hyperglycaemic clamp in horse...
