Chen, Zhanghua Yang, Tingyu Walker, Douglas I Thomas, Duncan C Qiu, Chenyu Chatzi, Leda Alderete, Tanya L Kim, Jeniffer S Conti, David V Breton, Carrie V
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Published in
Environment international
Per- and polyfluoroalkyl substances (PFASs) exposure is ubiquitous among the US population and has been linked to adverse health outcomes including cardiometabolic diseases, immune dysregulation and endocrine disruption. However, the metabolic mechanism underlying the adverse health effect of PFASs exposure is unknown. The aim of this project is to...
Kupsco, Allison Gonzalez, Gwendolyn Baker, Brennan H Knox, Julia M Zheng, Yinan Wang, Sheng Chang, Dou Schwartz, Joel Hou, Lifang Wang, Yinsheng
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Published in
Environment international
Post-transcriptional modifications of RNA constitute fundamental mechanisms of gene regulation. N6-methyladenosine (m6A) is critical for health and disease and is modulated by cellular stressors. However, associations between environmental exposures and m6A have not been studied in humans. We aimed to examine associations between tobacco smoking an...
Wang, Zhiyuan Chen, Qiuwen Zhang, Jianyun Guan, Tiesheng Chen, Yuchen Shi, Wenqing
Published in
Environment international
The widespread occurrence of antibiotic resistance genes (ARGs) throughout aquatic environments has raised global concerns for public health, but understanding of the emergence and propagation of ARGs in diverse environmental media remains limited. This study investigated the occurrence and spatio-temporal patterns of six classes of ARGs in cyanoba...
Schneider, Thierry Oughton, Deborah Cardis, Elisabeth
Published in
Environment international
Boberg, Julie Johansson, Hanna K L Axelstad, Marta Olsen, Gustav P M Johansen, Mathias Holmboe, Stine A Andersson, Anna-Maria Svingen, Terje
Published in
Environment international
Regulation of chemicals with endocrine disrupting properties depend on the use of the chemical rather than its intrinsic properties. Within the EU, the only criteria currently in place for identifying an endocrine disrupting chemical (EDC) are those developed for biocidal and plant protection products. We argue that ECHA/EFSA guidance for assessing...
Hu, Ying Yao, Mingyao Liu, Yumeng Zhao, Bin
Published in
Environment international
Most epidemiological studies usually employ ambient air pollutant concentrations as a proxy of personal exposure to air pollutants originating outdoors, which could lead to a biased estimation of health effects. Herein, we modeled infiltration and exposure factors as the modifications of personal exposure to ambient PM2.5, PM10, O3, NO2, and SO2 fo...
Liu, Yingxue Li, An Buchanan, Susan Liu, Weiping
Published in
Environment international
Per- and polyfluoroalkyl substances (PFASs) are ubiquitous in the environment, making it inevitable for humans to be exposed to these pollutants. The exposure begins while in utero and continues in infancy, during the potentially most sensitive early stages of life. This review summarizes the current knowledge on pre- and neo-natal exposures based ...
Wang, Panliang Qiao, Ziru Li, Xunan Wu, Dong Xie, Bing
Published in
Environment international
The prevalence and dissemination of antibiotic resistance genes (ARGs) have been globally gained increasing concerns. However, the fate and spread of ARGs in food waste (FW) and its large-scale biotreatment systems are seldomly understood. Here, we investigated the initial and biologically treated FW in two major FW treatment systems of aerobic fer...
Arbuthnott, Katherine Hajat, Shakoor Heaviside, Clare Vardoulakis, Sotiris
Published in
Environment international
There is a well-established relationship between temperature and mortality, with older individuals being most at risk in high-income settings. This raises the question of the degree to which lives are being shortened by exposure to heat or cold. Years of life lost (YLL) take into account population life expectancy and age at which mortality occurs....
Jung, Eun Mi Kim, Kyoung-Nam Park, Hyesook Shin, Hwashin H Kim, Hae Soon Cho, Su Jin Kim, Soon Tae Ha, Eun Hee
Published in
Environment international
Findings from previous studies on the association between exposure to fine particulate matter (PM2.5) and the risk of infant mortality were inconsistent. Thus, two main objectives of our study were to examine the association between exposure to PM2.5 and specified infant mortality and to identify critical trimesters. We retrospectively created a bi...
