Hong, Seok-Woo Lee, Jinmi Kim, Min Jeong Moon, Sun Joon Kwon, Hyemi Park, Se Eun Rhee, Eun-Jung Lee, Won-Young
Published in
Endocrinology and metabolism (Seoul, Korea)
There is a great need to discover factors that could protect pancreatic β-cells from apoptosis and thus prevent diabetes mellitus. Clusterin (CLU), a chaperone protein, plays an important role in cell protection in numerous cells and is involved in various cellular mechanisms, including autophagy. In the present study, we investigated the protectiv...
Park, Byung Kwan
Published in
Endocrinology and metabolism (Seoul, Korea)
Image-guided radiofrequency ablation (RFA) has been accepted as a minimally invasive treatment for adrenal tumors in patients who are unable to undergo adrenalectomy. Accordingly, this treatment has become more readily available for treating functioning or non-functioning adrenal masses. Thus, endocrinologists need a better understanding of percuta...
Jeong, In-Kyung Kim, Sung-Rae
Published in
Endocrinology and metabolism (Seoul, Korea)
While randomized controlled trials provide useful information about drug safety and efficacy, they do not always reflect the observed results in the real world. The prospective, observational, non-comparative trial in South Korea was designed to evaluate the efficacy and safety of pitavastatin in clinical practice in 28,343 patients. This study was...
Bai, Yanhua Kakudo, Kennichi Jung, Chan Kwon
Published in
Endocrinology and metabolism (Seoul, Korea)
Advances in medical sciences and evidence-based medicine have led to momentous changes in classification and management of thyroid neoplasms. Much progress has been made toward avoiding overdiagnosis and overtreatment of thyroid cancers. The new 2017 World Health Organization (WHO) classification of thyroid neoplasms updated the diagnostic criteria...
Lin, Yu-Fang Peng, Kang-Yung Chang, Chia-Hui Hu, Ya-Hui Wu, Vin-Cent Chung, Shiu-Dong
Published in
Endocrinology and metabolism (Seoul, Korea)
Data on the effects of excess aldosterone on glucose metabolism are inconsistent. This study compared the changes in glucose metabolism in patients with primary aldosteronism (PA) after adrenalectomy or treatment with a mineralocorticoid receptor antagonist (MRA). Overall, 241 patients were enrolled; 153 underwent adrenalectomy and 88 received an M...
Dao, Tam Green, Alexander E Kim, Yun A Bae, Sung-Jin Ha, Ki-Tae Gariani, Karim Lee, Mi-Ra Menzies, Keir J Ryu, Dongryeol
Published in
Endocrinology and metabolism (Seoul, Korea)
The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns. Sarcopenia is a condition which is defined by the gradual loss of skeletal muscle mass and function with age. In research and clinical practice, sarcopenia is recognized as a component...
Williams, Rachel Periasamy, Muthu
Published in
Endocrinology and metabolism (Seoul, Korea)
Obesity-associated metabolic illnesses are increasing at an alarming rate in Asian countries. A common feature observed in the Asian population is a higher incidence of abdominal obesity-the "skinny-fat" Asian syndrome. In this review, we critically evaluate the relative roles of genetics and environmental factors on fat distribution in Asian popul...
Kim, Ji-Hoon Choi, Man Ho
Published in
Endocrinology and metabolism (Seoul, Korea)
The adrenal gland plays a pivotal role in an organism's health span by controlling the endocrine system. Decades of research on the adrenal gland have provided multiscale insights into the development and maintenance of this essential organ. A particularly interesting finding is that founder stem/progenitor cells participate in adrenocortical devel...
Kwak, JungHak Lee, Kyu Eun
Published in
Endocrinology and metabolism (Seoul, Korea)
Since the introduction of minimally invasive surgery, laparoscopic adrenalectomy has become the main treatment option for adrenal masses. Various studies have reported that laparoscopic adrenalectomy showed fewer postoperative complications and faster recovery than conventional open adrenalectomy. Laparoscopic adrenalectomy can be performed through...
Kim, Jang-Il Kim, Su-Jin Xu, Zhen Kwak, JungHak Ahn, Jong-Hyuk Yu, Hyeong Won Chai, Young Jun Choi, June Young Lee, Kyu Eun
Published in
Endocrinology and metabolism (Seoul, Korea)
The use of intraoperative neuromonitoring (IONM) in thyroid surgery to preserve recurrent laryngeal nerve (RLN) function has been widely accepted. We aimed to evaluate the usefulness of IONM in reoperation for recurrent thyroid cancer patients to help identify the RLN and prevent vocal cord palsy (VCP). We analyzed 121 consecutive patients (with IO...