Leung, Kenneth Siu-Sing Ng, Timothy Ting-Leung Wu, Alan Ka-Lun Yau, Miranda Chong-Yee Lao, Hiu-Yin Choi, Ming-Pan Tam, Kingsley King-Gee Lee, Lam-Kwong Wong, Barry Kin-Chung Man Ho, Alex Yat
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Published in
Emerging infectious diseases
Initial cases of coronavirus disease in Hong Kong were imported from mainland China. A dramatic increase in case numbers was seen in February 2020. Most case-patients had no recent travel history, suggesting the presence of transmission chains in the local community. We collected demographic, clinical, and epidemiologic data from 50 patients, who a...
Pickering, Brad S Smith, Greg Pinette, Mathieu M Embury-Hyatt, Carissa Moffat, Estella Marszal, Peter Lewis, Charles E
Published in
Emerging infectious diseases
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease, has been shown to infect several species. The role of domestic livestock and associated risks for humans in close contact with food production animals remains unknown for many species. Determining the susceptibility of pigs to SARS-CoV-2 is crit...
Feehan, Amy K Velasco, Cruz Fort, Daniel Burton, Jeffrey H Price-Haywood, Eboni G Katzmarzyk, Peter T Garcia-Diaz, Julia Seoane, Leonardo
Published in
Emerging infectious diseases
By using paired molecular and antibody testing for severe acute respiratory syndrome coronavirus 2 infection, we determined point prevalence and seroprevalence in Louisiana, USA, during the second phase of reopening. Infections were highly variable by race and ethnicity, work environment, and ZIP code. Census-weighted seroprevalence was 3.6%, and p...
Guzzetta, Giorgio Riccardo, Flavia Marziano, Valentina Poletti, Piero Trentini, Filippo Bella, Antonino Andrianou, Xanthi Del Manso, Martina Fabiani, Massimo Bellino, Stefania
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Published in
Emerging infectious diseases
On March 11, 2020, Italy imposed a national lockdown to curtail the spread of severe acute respiratory syndrome coronavirus 2. We estimate that, 14 days after lockdown, the net reproduction number had dropped below 1 and remained stable at »0.76 (95% CI 0.67-0.85) in all regions for >3 of the following weeks.
Haley, Connie A Macias, Patricia Jasuja, Supriya Jones, Betsy A Rowlinson, Marie-Claire Jaimon, Roshni Onderko, Pennelyn Darnall, Elaine Gomez, Maria E Peloquin, Charles
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Published in
Emerging infectious diseases
The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose.
Totura, Allison Livingston, Virginia Frick, Ondraya Dyer, David Nichols, Donald Nalca, Aysegul
Published in
Emerging infectious diseases
Emerging coronaviruses are a global public health threat because of the potential for person-to-person transmission and high mortality rates. Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012, causing lethal respiratory disease in »35% of cases. Primate models of coronavirus disease are needed to support development of therape...
Moss, Robert Wood, James Brown, Damien Shearer, Freya M Black, Andrew J Glass, Kathryn Cheng, Allen C McCaw, James M McVernon, Jodie
Published in
Emerging infectious diseases
The ability of health systems to cope with coronavirus disease (COVID-19) cases is of major concern. In preparation, we used clinical pathway models to estimate healthcare requirements for COVID-19 patients in the context of broader public health measures in Australia. An age- and risk-stratified transmission model of COVID-19 demonstrated that an ...
Akinbami, Lara J Vuong, Nga Petersen, Lyle R Sami, Samira Patel, Anita Lukacs, Susan L Mackey, Lisa Grohskopf, Lisa A Shehu, Amy Atas, Jenny
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Published in
Emerging infectious diseases
To estimate seroprevalence of severe acute respiratory syndrome 2 (SARS-CoV-2) among healthcare, first response, and public safety personnel, antibody testing was conducted in emergency medical service agencies and 27 hospitals in the Detroit, Michigan, USA, metropolitan area during May-June 2020. Of 16,403 participants, 6.9% had SARS-CoV-2 antibod...
Wang, Xutong Du, Zhanwei Huang, George Pasco, Remy F Fox, Spencer J Galvani, Alison P Pignone, Michael Johnston, S Claiborne Meyers, Lauren Ancel
Published in
Emerging infectious diseases
As coronavirus disease spreads throughout the United States, policymakers are contemplating reinstatement and relaxation of shelter-in-place orders. By using a model capturing high-risk populations and transmission rates estimated from hospitalization data, we found that postponing relaxation will only delay future disease waves. Cocooning vulnerab...
Wiemken, Timothy L Rutschman, Ana Santos Niemotka, Samson L Hoft, Daniel
Published in
Emerging infectious diseases
Computational surveillance of pneumonia and influenza mortality in the United States using FluView uses epidemic thresholds to identify high mortality rates but is limited by statistical issues such as seasonality and autocorrelation. We used time series anomaly detection to improve recognition of high mortality rates. Results suggest that anomaly ...