Wang, Kun Wu, Changshuai Xu, Jian Zhang, Baohui Zhang, Xiaowang Gao, Zhenglian Xia, Zhengyuan
Published in
EClinicalMedicine
The 2019 novel coronavirus disease (COVID-19) can complicate the perioperative course to increase postoperative mortality in operative patients, and also is a serious threat to medical staff. However, studies summarizing the impact of COVID-19 on the perioperative mortality of patients and on the safety of medical staff are lacking. We searched Pub...
Ruszkiewicz, Dorota M Sanders, Daniel O'Brien, Rachel Hempel, Frederik Reed, Matthew J Riepe, Ansgar C Bailie, Kenneth Brodrick, Emma Darnley, Kareen Ellerkmann, Richard
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Published in
EClinicalMedicine
There is an urgent need to rapidly distinguish COVID-19 from other respiratory conditions, including influenza, at first-presentation. Point-of-care tests not requiring laboratory- support will speed diagnosis and protect health-care staff. We studied the feasibility of using breath-analysis to distinguish these conditions with near-patient gas chr...
Sze, Shirley Pan, Daniel Nevill, Clareece R Gray, Laura J Martin, Christopher A Nazareth, Joshua Minhas, Jatinder S Divall, Pip Khunti, Kamlesh Abrams, Keith R
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Published in
EClinicalMedicine
Patients from ethnic minority groups are disproportionately affected by Coronavirus disease (COVID-19). We performed a systematic review and meta-analysis to explore the relationship between ethnicity and clinical outcomes in COVID-19. Databases (MEDLINE, EMBASE, PROSPERO, Cochrane library and MedRxiv) were searched up to 31st August 2020, for stud...
Gounder, Dr Praveen Trotman, Prof Judith
Published in
EClinicalMedicine
Guisado-Vasco, Pablo Valderas-Ortega, Sofia Carralón-González, Maria Maravillas Roda-Santacruz, Ana González-Cortijo, Lucia Sotres-Fernández, Gabriel Martí-Ballesteros, Eva María Luque-Pinilla, José Manuel Almagro-Casado, Elena La Coma-Lanuza, Félix J
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Published in
EClinicalMedicine
The COVID-19 outbreak challenges the Spanish health system since March 2020. Some available therapies (antimalarials, antivirals, biological agents) were grounded on clinical case observations or basic science data. The aim of this study is to describe the characteristics and impact of different therapies on clinical outcomes in a cohort of severe ...
Norris, Keith Gonzalez, Cynthia
Published in
EClinicalMedicine
Cilloni, Lucia Fu, Han Vesga, Juan F Dowdy, David Pretorius, Carel Ahmedov, Sevim Nair, Sreenivas A. Mosneaga, Andrei Masini, Enos Sahu, Suvanand
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Published in
EClinicalMedicine
Background Routine services for tuberculosis (TB) are being disrupted by stringent lockdowns against the novel SARS-CoV-2 virus. We sought to estimate the potential long-term epidemiological impact of such disruptions on TB burden in high-burden countries, and how this negative impact could be mitigated. Methods We adapted mathematical models of TB...
Levaillant, Mathieu Levaillant, Lucie Lerolle, Nicolas Vallet, Benoît Hamel-Broza, Jean-François
Published in
EClinicalMedicine
Background Students’ choice of medical specialties has evolved throughout year, with a growing interest in quality of life and in technological specialties. We investigated the repartition of such choices in the world and its influencing factors with a focus on the gender's influence, for helping policy-makers to deal with medical shortage and terr...
Burton, Paul R
Published in
EClinicalMedicine
Li, Honggang Xiao, Xingyuan Zhang, Jie Zafar, Mohammad Ishraq Wu, Chunlin Long, Yuting Lu, Wei Pan, Feng Meng, Tianqing Zhao, Kai
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Published in
EClinicalMedicine
Background The current study aimed to determine the impact of SARS-CoV-2 infection on male fertility. Methods This is a single-center, hospital-based observational study that included autopsied testicular and epididymal specimens of deceased COVID-19 male patients ( n =6) and recruited recovering COVID-19 inpatients ( n =23) with an equal number of...
