McNally, Bridgette B Carey, Elizabeth J
Published in
Digestive diseases and sciences
Standard of care treatment for AIH includes prednisone monotherapy or dual therapy prednisone-azathioprine. However, many hepatologists alternatively use azathioprine monotherapy to avoid side effects of long-term corticosteroids. To determine whether azathioprine monotherapy is comparable to dual prednisone-azathioprine for maintenance of remissio...
Turner, Kevin O Genta, Robert M Sonnenberg, Amnon
Published in
Digestive diseases and sciences
The causes for the occurrence of goblet cells at the gastroesophageal junction (GEJ-GC) are unknown. The aim of our study was to compare the concurrent histologic changes of the stomach in (1) patients with GEJ-GC, but without Barrett's esophagus (BE) to those in (2) patients with BE and in (3) controls without GEJ-GC or BE. We used an electronic d...
Kaunitz, Jonathan D Keeffe, Meghan
Published in
Digestive diseases and sciences
Lingblom, Christine Albinsson, Sofie Johansson, Leif Larsson, Helen Wennerås, Christine
Published in
Digestive diseases and sciences
Noninvasive methods to assess treatment response in eosinophilic esophagitis are needed. Our aim was to determine whether a blood-based biomarker panel centered on immune parameters could identify histologic response to treatment in eosinophilic esophagitis patients. A pilot study involving adult patients with active eosinophilic esophagitis recrui...
Triadafilopoulos, George Lombard, Charles
Published in
Digestive diseases and sciences
Jiang, Zhi-Feng Zhang, Lin
Published in
Digestive diseases and sciences
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides and play important roles in a variety of diseases. LncRNAs are involved in many biologic processes including cell differentiation, development, and apoptosis. The intestinal barrier is considered one of the most important protective barriers in humans. Severe damage or dysfu...
Shin, Jung Woo Jeong, Joonho Jung, Seok Won Lee, Seung Bum Park, Bo Ryung Kim, Min-Ju Park, Eun Ji Park, Neung Hwa
Published in
Digestive diseases and sciences
Adherence to medication and maintained virologic response (MVR) are related to the risk of adverse clinical outcomes. This study aimed to compare the efficacy of entecavir (ETV) and tenofovir disoproxil fumarate (TDF) in relation to the adverse clinical outcomes among chronic hepatitis B (CHB) patients stratified according to adherence to medicatio...
Hashimoto, Rintaro Lee, David P Samarasena, Jason B Chandan, Vishal S Guo, Wenchang Lee, John G Chang, Kenneth J
Published in
Digestive diseases and sciences
EUS-guided liver biopsy (EUS-LB) has been shown to be a safe and effective alternative to percutaneous liver biopsy. The optimal needle device and technique for EUS-LB is still evolving. The aim of this study was to compare the efficacy of two second-generation 19G fine-needle biopsy (FNB) (Franseen- and Fork-tip) devices for EUS-LB. This is a repe...
Sobani, Zain A Ling, Christina Rustagi, Tarun
Published in
Digestive diseases and sciences
The mainstay of management of acute cholecystitis has been surgical, with percutaneous gallbladder drainage in patients deemed high risk for surgical intervention. Endoscopic management of acute cholecytitis with transpapillary and transmural drainage of the gall bladder is emerging as a viable alternative in high-risk surgical patients. In this ar...
Cui, Ying Zhang, Jun Chen, Yan Chen, Le-Gao
Published in
Digestive diseases and sciences
Heparanase (HPSE) is considered to play an important role in the occurrence, development and carcinogenesis of ulcerative colitis (UC). There are no reports about the detection of HPSE mRNA in feces to predict UC activity and cancerization risk. To explore the feasibility and effectiveness of fecal epithelial HPSE mRNA in monitoring patients' UC ac...
