50th Anniversary of the EAGEN
Published in Digestive Diseases
From Regular Catharsis with Castor Oil to Recognizing the Importance of the Intestinal Microbiota
Published in Digestive Diseases
The need to shed light on the unknown aspects of pathophysiology of common disorders, such as gastrointestinal ones, has led researchers through last decades to study and define the role of microorganisms within the human intestine and their interactions with the host. The progress of technology has permitted the overcoming of culture-based methods...
Endoscopic Treatment of Obesity: From Past to Future
Published in Digestive Diseases
Background: Conventional approaches in the management of obesity offer only a limited potential for sustained weight loss. Moreover, bariatric surgery, although momentarily being the most effective weight-loss treatment, has some serious pitfalls, such as significant morbidity rate, high substantial costs and limited patient applicability. Hence, t...
Evolution and Revolution of Hepatitis C Management: From Non-A, Non-B Hepatitis Toward Global Elimination
Published in Digestive Diseases
Discovery of hepatitis C in 1989 allowed basic research to identify critical components of hepatitis C virus (HCV) structure and life cycle. Interferon (IFN)-α was introduced as first treatment for chronic hepatitis C and later was enhanced by pegylation, addition of ribavirin, and resulted in improved sustained virologic response. Better understan...
Peptic Ulcer: Chapter Closed?
Published in Digestive Diseases
The incidence of peptic ulcer disease (PUD) peaked in the late 19th century while transiting into the 20th century. With entry in the new millennium a significant decrease of PUD has occurred. However, demographic changes with an increasing elderly population associated with multiple comorbidities and polypharmacy became responsible for a persisten...
How to Prepare Educational Lecture: EAGEN 50 Years of Experience
Published in Digestive Diseases
Background: European Association of Gastroenterology, Endoscopy, and Nutrition for 50 years provided a good, professional teaching of gastroenterology across Europe by world-known experts. Teaching tips and tricks to achieve maximum effects are summarized in this review article. Summary: The good speaker should be motivated to teach the audience at...
Microscopic Colitis: A Challenging Disorder
Published in Digestive Diseases
Background: The clinical importance of microscopic colitis (MC) is increasing. This is explained by both the increasing incidence and the challenges posed by the disease. However, recent MC data also reveal a number of doubts and uncertainties. Summary: This review focuses on current knowledge of MC and highlights the various controversies and crit...
Nonalcoholic Fatty Pancreas Disease: Clinical Consequences
Published in Digestive Diseases
Metabolic syndrome and its components such as obesity, hypertriglyceridemia, type-2 diabetes mellitus (DM-T2), and arterial hypertension are unequivocally serious problems for every society. This is especially true in economically developed countries where the imbalance in lifestyle between caloric intake and caloric output still gets greater and g...
Why the N (Nutrition) was Added in the EAGEN Acronym?
Published in Digestive Diseases
Background: Nutrition has been neglected for a long time as an important factor in the pathogenesis of digestive diseases, but also in the treatment, despite Hippocrates long ago insisted “Let food be thy medicine and medicine be thy food.” Summary: New insights into the importance of nutrition in the emergence of disease, and especially in the fie...
Irritable Bowel Syndrome Subtypes: New Names for Old Medical Conditions
Published in Digestive Diseases
The irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder (FGID), also called disorders of the gut-brain interaction (DGBI). Over the years, the definition and classification of IBS suffered several conceptual changes. The work of the Rome Committees has largely contributed to the progress in knowledge and awareness...
