Yang, Jiaxi Zhang, Cuilin Chavarro, Jorge E Rich-Edwards, Janet W Wang, Molin Fawzi, Wafaie W Manson, JoAnn E Lee, I-Min Hu, Frank B Tobias, Deirdre K
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Published in
Diabetes care
We examined lifestyle factors with midlife weight change according to history of gestational diabetes mellitus (GDM) in a large longitudinal female cohort. In the Nurses' Health Study II, we categorized changes in lifestyle within 4-year periods and estimated their associations with concurrent changes in body weight (kilograms) among parous women a...
Fu, Zhenzhen Wu, Qinyi Guo, Wen Gu, Jingyu Zheng, Xuqin Gong, Yingyun Lu, Chenyan Ye, Jingya Ye, Xuan Jiang, Wanzi
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Published in
Diabetes care
To investigate the roles of insulin clearance and insulin secretion in the development of hyperinsulinemia in obese subjects and to reveal the association between insulin clearance and bile acids (BAs). In cohort 1, insulin secretion, sensitivity, and endogenous insulin clearance were evaluated with an oral glucose tolerance test in 460 recruited p...
Akturk, Halis Kaan Snell-Bergeon, Janet Kinney, Gregory L Champakanath, Anagha Monte, Andrew Shah, Viral N
Published in
Diabetes care
To differentiate diabetic ketoacidosis (DKA) from hyperglycemic ketosis due to cannabis hyperemesis syndrome (HK-CHS) in adults with type 1 diabetes. Of 295 adults with type 1 diabetes who were seen with DKA-related ICD-10 codes, 68 patients with 172 DKA events meeting the inclusion criteria were analyzed. Cannabis use was defined as a positive uri...
Steck, Andrea K Dong, Fran Geno Rasmussen, Cristy Bautista, Kimberly Sepulveda, Flor Baxter, Judith Yu, Liping Frohnert, Brigitte I Rewers, Marian J
Published in
Diabetes care
Children identified with stage 1 type 1 diabetes are at high risk for progressing to stage 3 (clinical) diabetes and require accurate monitoring. Our aim was to establish continuous glucose monitoring (CGM) metrics that could predict imminent progression to diabetes. In the Autoimmunity Screening for Kids study, 91 children who were persistently is...
Chao, Lily C Vidmar, Alaina P Georgia, Senta
Published in
Diabetes care
Mohammedi, Kamel Abouleka, Yawa Carpentier, Charlyne Potier, Louis Dubois, Severine Foussard, Ninon Rigalleau, Vincent Gautier, Jean-François Gourdy, Pierre Charpentier, Guillaume
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Published in
Diabetes care
The ACE insertion/deletion (I/D) polymorphism has been widely studied in people with diabetes, albeit not with regard to lower-limb amputation (LLA). We examined associations among this polymorphism, plasma ACE concentration, and LLA in people with type 1 diabetes. ACE I/D genotype and plasma ACE were assessed in three prospective cohorts of partic...
Nathan, Brandon M Redondo, Maria J Ismail, Heba Jacobsen, Laura Sims, Emily K Palmer, Jerry Skyler, Jay Bocchino, Laura Geyer, Susan Sosenko, Jay M
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Published in
Diabetes care
We assessed whether Index60, a composite measure of fasting C-peptide, 60-min C-peptide, and 60-min glucose, could improve the metabolic staging of type 1 diabetes for progression to clinical disease (stage 3) among autoantibody-positive (Ab+) individuals with normal 2-h glucose values (
Khatana, Sameed Ahmed M Illenberger, Nicholas Werner, Rachel M Groeneveld, Peter W Mitra, Nandita
Published in
Diabetes care
Food insecurity is associated with diabetes. The Supplemental Nutrition Assistance Program (SNAP) is the largest U.S. government food assistance program. Whether such programs impact diabetes trends is unclear. The objective of this study was to evaluate the association between changes in state-level policies affecting SNAP participation and county...
Dawed, Adem Y Yee, Sook Wah Zhou, Kaixin van Leeuwen, Nienke Zhang, Yanfei Siddiqui, Moneeza K Etheridge, Amy Innocenti, Federico Xu, Fei Li, Josephine H
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Published in
Diabetes care
Sulfonylureas, the first available drugs for the management of type 2 diabetes, remain widely prescribed today. However, there exists significant variability in glycemic response to treatment. We aimed to establish heritability of sulfonylurea response and identify genetic variants and interacting treatments associated with HbA1c reduction. As an i...
Lee, Christine G Heckman-Stoddard, Brandy Dabelea, Dana Gadde, Kishore M Ehrmann, David Ford, Leslie Prorok, Philip Boyko, Edward J Pi-Sunyer, Xavier Wallia, Amisha
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Published in
Diabetes care
To determine whether metformin or lifestyle modification can lower rates of all-cause and cause-specific mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. From 1996 to 1999, 3,234 adults at high risk for type 2 diabetes were randomized to an intensive lifestyle intervention, masked metformin, or placebo. P...
