Aslam, Aisha A. Baksh, R. Asaad Pape, Sarah E. Strydom, Andre Gulliford, Martin C. Chan, Li F. Herault, Yann Strydom, Andre Chan, Li Potier, Marie-Claude
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Published in
Diabetes Care
OBJECTIVE Down syndrome (DS) is the most common form of chromosomal trisomy. Genetic factors in DS may increase the risk for diabetes. This study aimed to determine whether DS is associated with an increased incidence of diabetes and the relationship with obesity across the life span compared with control patients. RESEARCH DESIGN AND METHODS This ...
Stefanovski, Darko Vajravelu, Mary E Givler, Stephanie De León, Diva D
Published in
Diabetes care
The aim of this study was to assess whether exendin-(9-39) will increase fasting and postprandial plasma glucose and decrease the incidence of hypoglycemia in children with hyperinsulinism (HI). This was an open-label, four-period crossover study. In periods 1 and 2, the effect of three different dosing regimens of exendin-(9-39) (group 1, 0.28 mg/...
Tornese, Gianluca Carletti, Claudia Giangreco, Manuela Nisticò, Daniela Faleschini, Elena Barbi, Egidio
Published in
Diabetes care
To find a carbohydrate (CHO) tolerance threshold for unannounced snacks to avoid the 2 h increase in glycemia (difference between pre- and postmeal blood glucose [ΔBG]) ≥50 mg/dL in advanced hybrid closed-loop (a-HCL) users. Fourteen children and adolescents with type 1 diabetes (7 females; mean age [± SD] 14.5 ± 3.6 years), users of the Medtronic ...
Wu, I-Wen Tsai, Tsung-Hsien Lo, Chi-Jen Chou, Yi-Ju Yeh, Chi-Hsiao Cheng, Mei-Ling Lai, Chi-Chun Sytwu, Huey-Kang Tsai, Ting-Fen
Published in
Diabetes Care
Schmittdiel, Julie A Adams, Alyce S Haire-Joshu, Debra Heisler, Michele Piatt, Gretchen A Ackermann, Ron Chin, Marshall H Gonzalez, Jeffrey S Manson, Spero M Narayan, K M Venkat
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Published in
Diabetes care
Chen, Xuan Affinati, Alison H Lee, Yungchun Turcu, Adina F Henry, Norah Lynn Schiopu, Elena Qin, Angel Othus, Megan Clauw, Dan Ramnath, Nithya
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Published in
Diabetes care
Type 1 diabetes mellitus (T1DM) is a rare, irreversible immune-related adverse event reported in patients receiving treatment with immune checkpoint inhibitors (ICI). However, clinical risk factors for ICI-induced T1DM (ICI-T1DM) and its impact on survival in patients remain unknown. We used Optum's Clinformatics Data Mart database for assessment o...
Holman, Naomi Wild, Sarah H Khunti, Kamlesh Knighton, Peter O'Keefe, Jackie Bakhai, Chirag Young, Bob Sattar, Naveed Valabhji, Jonathan Gregg, Edward W
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Published in
Diabetes care
To assess the incidence of remission of type 2 diabetes in routine care settings. People with type 2 diabetes (HbA1c ≥48 mmol/mol [6.5%] or
Oram, Richard A Sharp, Seth A Pihoker, Catherine Ferrat, Lauric Imperatore, Giuseppina Williams, Adrienne Redondo, Maria J Wagenknecht, Lynne Dolan, Lawrence M Lawrence, Jean M
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Published in
Diabetes care
Genetic risk scores (GRS) aid classification of diabetes type in White European adult populations. We aimed to assess the utility of GRS in the classification of diabetes type among racially/ethnically diverse youth in the U.S. We generated type 1 diabetes (T1D)- and type 2 diabetes (T2D)-specific GRS in 2,045 individuals from the SEARCH for Diabet...
Ueda, Peter Svanström, Henrik Hviid, Anders Eliasson, Björn Svensson, Ann-Marie Franzén, Stefan Gudbjörnsdottir, Soffia Hveem, Kristian Jonasson, Christian Wintzell, Viktor
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Published in
Diabetes care
Tuttle, Katherine R. Levin, Adeera Nangaku, Masaomi Kadowaki, Takashi Agarwal, Rajiv Hauske, Sibylle J. Elsäßer, Amelie Ritter, Ivana Steubl, Dominik Wanner, Christoph
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Published in
Diabetes Care
OBJECTIVE To assess the safety of empagliflozin in patients with type 2 diabetes and moderate to severe chronic kidney disease (CKD) (category G3–4) enrolled in clinical trials. RESEARCH DESIGN AND METHODS This analysis pooled data from 19 randomized, placebo-controlled, phase 1–4 clinical trials and 1 randomized, placebo-controlled extension study...
