Zhao, Hanbin Cao, Jian Mu, Huaqi Bi, Yang Shi, Yuan Wang, Yi
Published in
Developmental biology
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Agrawal, Khushboo Prabhakar, Sunil Bakthavachalu, Baskar Chaturvedi, Dhananjay
Published in
Developmental biology
Anatomical profiles of insects inform vector biology, comparative development and evolutionary studies with applications in forensics, agriculture and disease control. This study presents a comprehensive, high-resolution developmental profile of Anopheles stephensi, encompassing larval, pupal, and adult stages, obtained through microCT scanning. Th...
Gao, Xin Mukaibo, Taro Wei, Xiaolu Faustoferri, Roberta C. Oei, Maria S. Hwang, Seo-Kyoung Yan, Adela Jingyi Melvin, James E. Ovitt, Catherine E.
Published in
Developmental biology
Orlandi, Leona Rodriguez, Yoann Leostic, Anne Giraud, Corinne Lang, Maya-Laure Vialard, François Mauffré, Vincent Motte-Signoret, Emmanuelle
Published in
Developmental biology
After birth, the lungs must resorb the fluid they contain. This process involves multiple actors such as surfactant, aquaporins and ENaC channels. Preterm newborns often exhibit respiratory distress syndrome due to surfactant deficiency, and transitory tachypnea caused by a delay in lung liquid resorption. Our hypothesis is that surfactant, ENaC an...
Rees, Jenaid M Palmer, Michael A Gillis, J Andrew
Published in
Developmental biology
The gill slits of fishes develop from an iterative series of pharyngeal endodermal pouches that contact and fuse with surface ectoderm on either side of the embryonic head. We find in the skate (Leucoraja erinacea) that all gill slits form via a stereotypical sequence of epithelial interactions: 1) endodermal pouches approach overlying surface ecto...
Piacentino, Michael L Fasse, Aria J Camacho-Avila, Alexis Grabylnikov, Ilya Bronner, Marianne E
Published in
Developmental biology
During epithelial-to-mesenchymal transition (EMT), significant rearrangements occur in plasma membrane protein and lipid content that are important for membrane function and acquisition of cell motility. To gain insight into how neural crest cells regulate their lipid content at the transcriptional level during EMT, here we identify critical enhanc...
Dhouailly, Danielle
Published in
Developmental biology
Feathers originate as protofeathers before birds, in pterosaurs and basal dinosaurs. What characterizes a feather is not only its outgrowth, but its barb cells differentiation and a set of beta-corneous proteins. Reticula appear concomitantly with feathers, as small bumps on plantar skin, made only of keratins. Avian scales, with their own set of b...
Altbürger, Christian Rath, Meta Wehrle, Johanna Driever, Wolfgang
Published in
Developmental biology
The proneural factor Ascl1 is involved in several steps of neurogenesis, from neural progenitor maintenance to initiation of terminal differentiation and neuronal subtype specification. In neural progenitor cells, Ascl1 initiates the cell-cycle exit of progenitors, and contributes to their differentiation into mainly GABAergic neurons. Several cate...
Clements, Rhiannon Smith, Tyler Cowart, Luke Zhumi, Jennifer Sherrod, Alan Cahill, Aidan Hunter, Ginger L
Published in
Developmental biology
The self-organization of cells during development is essential for the formation of healthy tissues and requires the coordination of cell activities at local scales. Cytonemes, or signaling filopodia, are dynamic actin-based cellular protrusions that allow cells to engage in contact mediated signaling at a distance. While signaling filopodia have b...
Keating, Margaret Hagle, Ryan Osorio-Méndez, Daniel Rodriguez-Parks, Anjelica Almutawa, Sarah I Kang, Junsu
Published in
Developmental biology
Knock-in reporter (KI) animals are essential tools in biomedical research to study gene expression impacting diverse biological events. While CRISPR/Cas9-mediated genome editing allows for the successful generation of KI animals, several factors should be considered, such as low expression of the target gene, prevention of bacterial DNA integration...
