Published in Deutsche medizinische Wochenschrift (1946)
Secondary prevention of otherwise cryptogenic stroke in patients with patent foramen ovale (PFO) has been a matter of debate over nearly three decades. Main issues were that data essentially derived from case-control-studies for a long period and that results from the randomized controlled trials CLOSURE-I, PC Trial and RESPECT, which were publishe...
Published in Deutsche medizinische Wochenschrift (1946)
A delirium in patients in the intensive care unit (ICU) is a manifestation of a severe acute dysfunction of the brain. It has a high prevalence and is associated with a relevant increase in morbidity and mortality. A cholinergic deficit and dopaminergic overactivity are considered to be a cause of delirium. Polypharmacy, which is often present befo...
Published in Deutsche medizinische Wochenschrift (1946)
Mitral regurgitation (MR) is one of the most common valvular defects in the eldery. In patients suffering from heart failure, secondary MR is common and associated with worse prognosis. Due to the usually very high operative risk these patients are immensely under-treated. This leads to an increased need for interventional treatment strategies. Unt...
Published in Deutsche medizinische Wochenschrift (1946)
Clinicians are commonly confronted with the differential diagnosis of altered mental status, impaired cognition and altered level of consciousness in hospitalized patients including those admitted to medical, geriatric, emergency, intensive and post-operative care units. Although delirium is the most common acute neuropsychiatric condition in the a...
Published in Deutsche medizinische Wochenschrift (1946)
Unknown liver lesions represent a common clinical challenge, for example in the context of routine ultrasound examinations of primary care physicians. There are different data on the prevalence of primary liver lesions in the literature. As such, a forensic autopsy series described focal liver lesions in about 50 % of all examined men between 35 an...
Published in Deutsche medizinische Wochenschrift (1946)
Aortic valve stenosis is the most common valvular heart disease requiring treatment in Europe. Transcatheter aortic valve implantation (TAVI) has already been established as a standard therapy in patients with high but also intermediate risk.In the meantime, it is even being performed more frequently than surgical replacement in Germany.This articl...
Published in Deutsche medizinische Wochenschrift (1946)
Published in Deutsche medizinische Wochenschrift (1946)
Mit Caplacizumab steht eine wirkungsvolle neue Therapie der erworbenen thrombotisch-thrombozytopenischen Purpura zur Verfügung. Die Zeit bis zum klinischen Ansprechen und die Zahl der Rückfälle können deutlich reduziert werden. Liegt jedoch eine persistierende Autoimmunaktivität über den Therapiezeitraum hinaus vor, geht diese mit einem hohen Rückf...
Published in Deutsche medizinische Wochenschrift (1946)
The work-up of acute monoarthritis is challenging due to the abundance of differential diagnoses. In addition to a bacterial septic arthritis, which can, if not treated promptly, cause rapid irreversible joint damage, many diseases have to be considered: inflammatory rheumatic diseases, activated osteoarthritis, other infectious arthritis, cristal ...
Published in Deutsche medizinische Wochenschrift (1946)
Die Klinik der AMI ist mannigfaltig – mit meist letalen Folgen bei Diagnoseverzögerung. Serumparameter sind häufig überschätzt. In der Kasuistik war das diabetische Koma verantwortlich für die AMI. Wegweisend war die sonografische Darstellung von portal-venösem Gas, sodass zeitnah die lebensrettende Operation erfolgen konnte. Ein Ultraschall sollte...
