Published in Der Pharmacia Sinica
Analysis to the literature supports the assumption that the shelf life of many drugs, seems to be "longer" than their expiration dates, leading to unnecessary waste, higher pharmaceutical costs, and possibly reduced access to necessary drugs for some patients. This is of most significance for the current situation in Libya with the political unrest...
Published in Der Pharmacia Sinica
Acute conjunctivitis (AC) is a common disease in both developing and industrialized countries. Conjunctivitis is an inflammation of the conjunctiva usually occurs as a result of infection or allergy, resulting in a so-called "red eye" or "pink eye." Acute conjunctivitis can be viral in nature; however, as many as 78% of cases in children and half o...
Published in Der Pharmacia Sinica
Estrogen-responsive breast cancer cells, such as MCF7 and T47D cells, express both estrogen receptor ER and ERß. Indole-3-carbinol (I3C) strongly down-regulated ER protein and transcript levels, without altering the level of ERß protein, in both cell lines. In cells transfected with the ER promoter linked to a luciferase gene reporter, I3C ablated ...
Published in Der Pharmacia Sinica
Stroke is one of the common diseases responsible for morbidity and mortality worldwide. (Mukherjee and Patil) It is a problem in both developed and developing countries despite advancements in its treatment and management through drug therapy or surgical intervention. (Murray and Lopez) Drug interactions in stroke patients present a unique challeng...
Published in Der Pharmacia Sinica
Diltiazem hydrochloride was obtained from Elan Drug Technologies. PEO grade 303, Vitamin E, Mannitol and dicalcium phosphate dehydrate were obtained from Merck, Germany. Diltiazem HCl:PEO with a ratio of (1:1) was prepared and Matrix tablets with target weights of 240 mg for pure samples, 242.4 tablets containing Vit E and 300 mg for filler tablets...
Published in Der Pharmacia Sinica
Biography Dr Ling Peng is a leading expert in developing functional dendrimer nanosystems for drug delivery in biomedical applications. She has successfully established bio-inspired structurally flexible and self-assembling dendrimer nanosystems for drug and nucleic acid delivery. One of the dendrimers developed by her team has been scheduled in cl...
Published in Der Pharmacia Sinica
iMedPub Journals Abstract MicroRNAs are a class of negative regulators of gene expression. Evidences indicate that miRNAs involved in the pathogenesis of New type 2 diabetes(NT2D) through decrease the expression of the genes secreting insulin and increase expression of insulin secretion suppressing ones, as well as exocytosis, incorporate in New ty...
Published in Der Pharmacia Sinica
In this literature review, we will introduce mode of action and most of up-to-date reported methods that have been developed for determination of certain antipsychotic drugs such as risperidone, levetiracetam, sodium valproate and oxcarbazepine in their pure form, combined form with other drugs, combined form with degradation products, and in biolo...
Published in Der Pharmacia Sinica
iMedPub Journals Abstract As we know, Indonesia is more vulnerable to infectious disease. We focus our research on the development of curcumin and tetrahydrocurcumin analog as drug candidate of infectious disease in Indonesia. The analogs are PGV-0, PGV-1, THPGV-0 and THPGV-1. THPGV-0 has antibacterial activity against S. aureus and B. subtilis at ...
Published in Der Pharmacia Sinica
Biography Christiana completed her PhD at the age of 27 years from Rhodes University, Grahamstown South Africa. Her major research area is in computational chemistry and drug design. My bench studies produced over 200 antiparasitic compounds in which 149 compounds are novel with 6 research papers, two peer reviewed, which has been published, one su...
