Sharma, Jeetesh Prabha, Punit Sharma, Rohit Gupta, Shalini Dixit, Aparna
Published in
Cytotechnology
Myeloid leukemia is one of the major causes of deaths among elderly with very poor prognosis. Due to the adverse effects of existing chemotherapeutic agents, plant-derived components are being screened for their anti-leukemic potential. Momordica charantia (bitter gourd) possesses a variety of therapeutic activities. We have earlier demonstrated an...
Li, Jianping Wang, Ziming Li, Hecheng Cao, Jun Nan, Ning Zhai, Xiaoqiang Liu, Ying Chong, Tie
Published in
Cytotechnology
Prostate cancer (PC) is one of the most common types of cancers among men, referring to the uncontrolled growth of the prostate gland. It is increasingly recognized that the interaction of the glioma-associated oncogene (GLI) pathway and androgen receptor affects PC progression. Nevertheless, the effects of resveratrol on PC progression via Hedgeho...
Yuan, Haofeng Li, Yiqian Zou, Yun Cai, Chongyue Shi, Xiangmin Su, Yanfeng
Published in
Cytotechnology
In recent years, salinomycin has been shown to exert an anticancer effect in a variety of tumors; however, its function and mechanism in bladder cancer (BC) remain unclear. This study examined the effect of salinomycin on bladder cancer and analyzed its regulatory mechanism. T24 cells were treated with different concentrations of salinomycin to det...
Eder, Susanne Müller, Karin Chen, Shuai Schoen, Jennifer
Published in
Cytotechnology
Basic knowledge about cellular and molecular mechanisms underlying feline reproduction is required to improve reproductive biotechnologies in endangered felids. Commonly, the domestic cat ( Felis catus ) is used as a model species, but many of the fine-tuned, dynamic reproductive processes can hardly be observed in vivo. This necessitates the devel...
Li, Dingyun Wang, Ting Lai, Jiajun Zeng, Deqiang Chen, Weijuan Zhang, Xiaochong Zhu, Xiaofeng Zhang, Guoxiong Hu, Zhiwei
Published in
Cytotechnology
Ferroptosis is a regulated form of cell death driven by small molecules or conditions that induce lipid-based reactive oxygen species (ROS) accumulation. Cation channel transient receptor potential melastatin-2 (TRPM2) is crucial for cancer cell survival. Our bioinformatic analysis revealed that TRPM2 is associated with cellular responses to chemic...
Jafari, Davod Eslami, Seyed Sadegh Malih, Sara Tarighi, Parastoo
Published in
Cytotechnology
Vincristine-induced peripheral neuropathy (VIPN) is the main side effect and major reason for neuropathic pain in cancer survivors treated with vincristine. Vincristine, a chemotherapeutic antimitotic drug, is used frequently in combination chemotherapy. The primary purpose of the current study was to assess the protective effect of sodium selenite...
Fujita, Yasutaka Nishimura, Masuhiro Wada, Tamaki Komori, Natsuki Otoi, Takeshige
Published in
Cytotechnology
We evaluated a dimethyl sulfoxide (Me2SO)-free cryopreservation solution to freeze human adipose-derived mesenchymal stromal cells (hADSCs). In the first experiment, we compared the combined effects of 3% trehalose (3 T) and 5% dextran (5D) in lactated Ringer’s solution (LR) as a cryopreservation base solution containing 10% propylene glycol (PG). ...
Balakrishnan, Soumya Singh, I. S. Bright Puthumana, Jayesh
Published in
Cytotechnology
Despite the attempts that have started since the 1960s, not even a single cell line of marine molluscs is available. Considering the vast contribution of marine bivalve aquaculture to the world economy, the prevailing viral threats, and the dismaying lack of advancements in molluscan virology, the requirement of a marine molluscan cell line is indi...
Liu, Jiaojiao Ding, Cong Wang, Xiaolong Yang, Lu Liu, Xin Kang, Qiaozhen
Published in
Cytotechnology
Melanoma is the most aggressive skin cancer with increasing incidence and poor prognosis all over the world. Recent research has found that immunological abnormalities played a key role in the pathogenesis of melanoma. Increased understanding of tumor immune mechanisms has led to attract more attention for the potential of TLR agonists on treatment...
Mokuda, Sho Watanabe, Hirofumi Kohno, Hiroki Ishitoku, Michinori Araki, Kei Hirata, Shintaro Sugiyama, Eiji
Published in
Cytotechnology
Studies conducted using murine arthritis models have indicated that the use of in vitro-transcribed messenger RNA (IVT mRNA) is an effective therapeutic approach for joint diseases. However, the use of IVT mRNA in human synovial cells has not been widely studied. Recently, the outbreak of the novel coronavirus disease has accelerated the developmen...
