Dave, Rutvi Gautam Geevar, Tulasi Aaron, Sanjith Ninan Benjamin, Rohit Mammen, Joy Kumar, Snehil Vijayan, Ramya Gowri, Mahasampath Nair, Sukesh C
Published in
Cytometry. Part B, Clinical cytometry
Coated-platelets are sub-population of platelets "coated" with highly procoagulant proteins and phosphatidylserine that sustains thrombin generation. They are produced upon dual agonist stimulation by collagen and thrombin. This study was conducted to assess if there was any difference in the levels of coated-platelets in patients with primary intr...
Dannus, Louis-Thomas Mulliez, Aurélien Berger, Marc Bourgne, Céline Veyrat-Masson, Richard
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Cytometry. Part B, Clinical cytometry
The estimation of uncertainty in measurement for quantitative analyses is an international obligation of the ISO15189 standard for laboratories. The most widespread method is the Internal Quality Control and External Quality Assessment (IQC + EQA). We compared two methods to assess uncertainty in measurement for the quantification of the number of ...
Chitadze, Guranda Lettau, Marcus Peters, Christian Luecke, Stefanie Flüh, Charlotte Quabius, Elgar Susanne Synowitz, Michael Held-Feindt, Janka Kabelitz, Dieter
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Cytometry. Part B, Clinical cytometry
The activating Natural killer group 2 member D (NKG2D) receptor is typically expressed on NK cells, CD8 T lymphocytes, γδ T cells and small subsets of CD4 T lymphocytes. During the course of an extensive flow cytometry phenotyping of immune cells in the peripheral blood of patients with glioblastoma multiforme (GBM) we noticed an unexpected express...
Baráth, Sándor Mezei, Zoltán A Száraz-Széles, Marianna Hevessy, Zsuzsanna
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Cytometry. Part B, Clinical cytometry
Human leukocyte antigen B27 (HLA-B27) is an major histocompatibility complex Class I cell surface antigen that shows strong association with spondylarthropathies. Although polymerase chain reaction (PCR) is the gold standard method for HLA-B27 detection, monoclonal antibodies, and flow cytometric analysis is also frequently used. We aimed to compar...
Hafeez, Safina Mnayer, Laila O DiGiuseppe, Joseph A
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Cytometry. Part B, Clinical cytometry
Huang, Shuxin Liang, Chaofeng Zhao, Yujie Deng, Tairan Tan, Jiaxiong Zha, Xianfeng Li, Yangqiu Chen, Shaohua
Published in
Cytometry. Part B, Clinical cytometry
T cell dysregulation is a common event in leukemia. Recent findings have indicated that aberrant expression of immune checkpoint proteins may be associated with disease relapse and progression in acute myeloid leukemia (AML). TOX, a transcription factor in the HMG-box protein superfamily, was found to be a potential target for immunotherapy not onl...
Rosenberg, Carina A Bill, Marie Maguire, Orla Petersen, Marianne A Kjeldsen, Eigil Hokland, Peter Ludvigsen, Maja
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Cytometry. Part B, Clinical cytometry
Studies in T-cell acute lymphoblastic leukemia (T-ALL) have shown that leukemic blast populations may display immunophenotypic heterogeneity. In the clinical setting, evaluation of measurable residual disease during treatment and follow-up is highly dependent on knowledge of the diversity of blast subsets. Here, we set out to evaluate whether varia...
Eveillard, Marion Béné, Marie C Hérault, Olivier
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Cytometry. Part B, Clinical cytometry
Mandy, Frank
Published in
Cytometry. Part B, Clinical cytometry
Gayet, Mylene Leymarie, Vincent Derouault, Paco Guérin, Estelle Vaidié, Julien Pascal, Virginie Boulin, Mélanie Dmytruk, Nataliya Chauzeix, Jasmine Trimoreau, Franck
...
Published in
Cytometry. Part B, Clinical cytometry
Differential diagnosis of Waldenström macroglobulinemia (WM) with other indolent B-cell malignancies is still a challenge. Here, we propose an original and simple analysis of routine flow cytometry (FCM) unraveling the characteristic ongoing plasma cell (PC) differentiation of WM tumor B-cells. FCM analysis of both B-cells and PC was performed on a...