Li, Hai-Ling Gao, Xiu-Feng Li, Jing-Ji Wan, Ming-Xia Zhang, Guo-Qi Li, Yong-Sheng
Published in
Current pharmaceutical biotechnology
Uricase (Uox) is a major drug in gout and a supplementary drug in cancer treatment. Because allergic reactions caused by Uox limit its clinical application,10% Co/EDTA was used to chemically modify Uox from A. flavus to reduce its immunogenicity. The immunogenicity of Uox and 10% Co/EDTA-Uox was examined by determining the antibody titer and concen...
Peruch, Michela Addobbati, Riccardo Padovano, Martina Scopetti, Matteo Concato, Monica Radaelli, Davide D'Errico, Stefano
Published in
Current pharmaceutical biotechnology
In recent years, the phenomenon of the production and trade of synthetic cannabinoids has grown, becoming a public health issue worldwide. The recent access- to the ED of the hospital of Trieste- of people who complained of episodes of hallucinations, sensation of poisoning, tachycardia, and air hunger following the inhalation of "Che Sballo platin...
Arora, Sunny Kumar, Shailender Kumar, Pardeep
Published in
Current pharmaceutical biotechnology
Diabetes mellitus is a long-term chronicle disorder with a high prevalence rate worldwide. Continuous blood glucose and lifestyle monitoring enabled the control of blood glucose dynamics through machine learning applications using data created by various popular sensors. This survey aims to assess various classical time series, neural networks and ...
Ranjbar, Reza Ebrahimi, Amir Sahebkar, Amirhossein
Published in
Current pharmaceutical biotechnology
Helicobacter pylori infection is a common health problem, which can cause gastric and extragastric diseases. Accurate detection of H. pylori is critical for appropriate patient management and bacterial eradication. In this regard, there are several methods for the diagnosis of H. pylori infection, which are classically divided into two major groups...
Bahadur, Shiv Sharma, Manisha
Published in
Current pharmaceutical biotechnology
Psoriasis has been considered as a chronic inflammatory skin disease which leads to the dysfunction of immune systems. According to the World Psoriasis Day consortium, psoriasis affects around 125 million individuals globally or about 2% to 3% of the overall population. Most of the conventional drug delivery systems primarily attempt to relieve sym...
Heydari, Mojtaba Khalili, Mohammad Reza Nowroozzadeh, Mohammad Hossein Bamdad, Shahram Sahebkar, Amirhossein Shariati, Mohammad Ali Thiruvengadam, Muthu
Published in
Current pharmaceutical biotechnology
Curcumin is the main active constituent of the medicinal plant Curcuma longa L., used traditionally as a medicinal spice in several ancient civilizations. Different preclinical and clinical studies support the anti-inflammatory properties of curcumin in various inflammatory diseases. As inflammation has an essential role in the pathophysiology of m...
Wang, Yidi Yuan, Huaibo Wang, Suisui Zeng, Tingting
Published in
Current pharmaceutical biotechnology
The treatment of diabetes with plant ingredients such as in Traditional Chinese Medicine (TCM) is an alternative to classical chemotherapy. This study aims to explore the hypoglycemic effect of Trichosanthes pericarpium powder (TP) and intestinal bacteria transplantation in type 2 diabetic mice. The relationship between intestinal bacteria transpla...
Shakib, Pegah Marzban, Abdolrazagh Mardanshah, Omid Fallahi, Shirzad Khan, Israr Ali Azarhazin, Mohammad Cheraghipour, Kourosh
Published in
Current pharmaceutical biotechnology
Drug resistance is a current issue affecting parasites caused by Plasmodium. Therefore, researchers have expanded their studies on nanoparticles to find new and effective drugs that can treat drug-resistant strains. The present study systematically investigates the effect of different nanoparticles, including metal, polymer, and lipid nanoparticles...
Humaira, Bukhari, Sayyad Ali Raza Shakir, Hafiz Abdullah Khan, Muhammad Saeed, Shagufta Ahmad, Irfan Irfan, Muhammad
Published in
Current pharmaceutical biotechnology
Currently, nanobiotechnology represents a leading research area that primarily focuses on the safe, eco-friendly synthesis of biocompatible metal oxide nanoparticles. Among these, biosynthesized cerium oxide nanoparticles have particularly received attention in medical science as their unique surface chemistry and dual oxidation state make them exc...
Roy, Zinal Bansal, Raveena Siddiqui, Lubna Chaudhary, Nidhee
Published in
Current pharmaceutical biotechnology
Antioxidant enzymes being an integral part of the defense mechanism have a crucial role in cellular metabolism, essential for healthy growth and living of the cells. The main function is to scavenge and degrade the free radicals, reactive oxygen species (ROS), and reactive nitrogen species (RNS). Endogenous antioxidant enzymes present in mitochondr...
