Lewiecki, E Michael Jackson, Avery 3rd Lake, Anne F Carey, John J Belaya, Zhanna Melnichenko, Galina A Rochelle, Rachelle
Published in
Current osteoporosis reports
This review describes the global development of a model of technology-enabled collaborative learning for healthcare professionals called Project ECHO (Extension for Community Healthcare Outcomes) and its applications for the management of patients with skeletal diseases. The prototype Bone Health TeleECHO was established in 2015, with others now op...
Matsuo, Koji Chavez, Robert Dalton Barruet, Emilie Hsiao, Edward C
Published in
Current osteoporosis reports
Heterotopic ossification (HO) is associated with inflammation. The goal of this review is to examine recent findings on the roles of inflammation and the immune system in HO. We examine how inflammation changes in fibrodysplasia ossificans progressiva, in traumatic HO, and in other clinical conditions of HO. We also discuss how inflammation may be ...
Viceconti, Marco Qasim, Muhammad Bhattacharya, Pinaki Li, Xinshan
Published in
Current osteoporosis reports
The original version "Are CT-Based Finite Element Model Predictions of Femoral Bone Strengthening Clinically Useful?"
Lekkala, Sashank Taylor, Erik A Hunt, Heather B Donnelly, Eve
Published in
Current osteoporosis reports
Individuals with type 1 and type 2 diabetes mellitus (T1DM, T2DM) have an increased risk of bone fracture compared to non-diabetic controls that is not explained by differences in BMD, BMI, or falls. Thus, bone tissue fracture resistance may be reduced in individuals with DM. The purpose of this review is to summarize work that analyzes the effects...
Mitchell, Paul J Cooper, Cyrus Fujita, Masaki Halbout, Philippe Åkesson, Kristina Costa, Matthew Dreinhöfer, Karsten E Marsh, David R Lee, Joon-Kiong Chan, Ding-Cheng Derrick
...
Published in
Current osteoporosis reports
This review sought to describe quality improvement initiatives in fragility fracture care and prevention. A major care gap persists throughout the world in the secondary prevention of fragility fractures. Systematic reviews have confirmed that the Fracture Liaison Service (FLS) model of care is associated with significant improvements in rates of b...
Stepan, Jan J Hruskova, Hana Kverka, Miloslav
Published in
Current osteoporosis reports
The goal of the review is to assess the appropriateness of menopausal hormone therapy (MHT) for the primary prevention of bone loss in women at elevated risk in the early years after menopause. Estrogen alone or combined with progestin to protect the uterus from cancer significantly reduces the risk of osteoporosis-related fractures. MHT increases ...
French, S Choden, S Schmajuk, Gabriela
Published in
Current osteoporosis reports
The aims of this review are to summarize current performance for osteoporosis quality measures used by Centers for Medicare and Medicaid (CMS) for pay-for-performance programs and to describe recent quality improvement strategies around these measures. Healthcare Effectiveness Data and Information (HEDIS) quality measures for the managed care popul...
Sharma, Anuj K Shi, Xingming Isales, Carlos M McGee-Lawrence, Meghan E
Published in
Current osteoporosis reports
The development of adiposity in the bone marrow, known as marrow adipose tissue (MAT), is often associated with musculoskeletal frailty. Glucocorticoids, which are a key component of the biological response to stress, affect both bone and MAT. These molecules signal through receptors such as the glucocorticoid receptor (GR), but the role of the GR ...
Tencerova, Michaela Okla, Meshail Kassem, Moustapha
Published in
Current osteoporosis reports
The goal of this review is to discuss the role of insulin signaling in bone marrow adipocyte formation, metabolic function, and its contribution to cellular senescence in relation to metabolic bone diseases. Insulin signaling is an evolutionally conserved signaling pathway that plays a critical role in the regulation of metabolism and longevity. Bo...
Sadie-Van Gijsen, Hanel
Published in
Current osteoporosis reports
To review the available literature regarding a possible relationship between vitamin D and bone marrow adipose tissue (BMAT), and to identify future avenues of research that warrant attention. Results from in vivo animal and human studies all support the hypothesis that vitamin D can suppress BMAT expansion. This is achieved by antagonizing adipoge...
