Mondejar, Victoria Patsalides, Athos
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewIdiopathic intracranial hypertension (IIH) is a disorder characterized by long-standing elevated intracranial pressure (ICP). As the name applies, no uniform cause has been identified. IIH is typically characterized by headaches, pulsatile tinnitus, and visual deterioration.Recent FindingsAnomalies in cerebrospinal fluid (CSF) abso...
Youssef, Gilbert Miller, Julie J.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewLow-grade gliomas (LGG) are a group of primary brain tumors that arise from supporting glial cells. They are characterized by a mutation in the isocitrate dehydrogenase (IDH) enzyme and include astrocytomas and oligodendrogliomas. They usually affect young adults, and their main treatment consists of surgical resection, followed by...
Maguire, Rebecca Maguire, Phil
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewIn spite of recent advances in treatment, many people with multiple sclerosis (MS) require ongoing care and support. Informal caregivers can experience burden as a result of their role, with possible implications for quality of life (QOL). We review recent research examining MS caregiver experience to (1) understand current risk fa...
Feldman, Alexander Z. Jennings, Lawrence J. Wadhwani, Nitin R. Brat, Daniel J. Horbinski, Craig M.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewMolecular testing has become essential for the optimal workup of central nervous system (CNS) tumors. There is a vast array of testing from which to choose, and it can sometimes be challenging to appropriately incorporate findings into an integrated report. This article reviews various molecular tests and provides a concise overvie...
Liu, Elisa K. Sulman, Erik P. Wen, Patrick Y. Kurz, Sylvia C.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewGlioblastoma (GBM) is the most common malignant primary brain tumor, and the available treatment options are limited. This article reviews the recent preclinical and clinical investigations that seek to expand the repertoire of effective medical and radiotherapy options for GBM.Recent FindingsRecent phase III trials evaluating chec...
Oset, Magdalena Stasiolek, Mariusz Matysiak, Mariola
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewMultiple sclerosis (MS) is a demyelinating disease of the central nervous system that mainly affects young adults and that is one of the leading causes of disability in this age group, with cognitive impairment occurring early in the course of the disease. This article summarizes the current knowledge about cognitive dysfunction in...
Lai, Joshua Dilli, Esma
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewTo provide an updated review of the pathophysiology, diagnosis, and management of migraine with aura.Recent FindingsThalamic and other subcortical regions may play a role in the pathophysiology of migraine. There is inter-patient and intra-patient attack variability in the characteristics of typical aura especially visual aura symp...
Chan, Tommy L. H. Hale, Troy D. Steenerson, Kristen K.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewTo provide an overview of vestibular lab testing and to familiarize the reader with common results observed in headache patients with dizziness.Recent FindingsThe latest research indicates variable levels of both peripheral and central vestibular dysfunction in headache populations with dizziness. Mechanisms may include vestibuloce...
Datta, Neil Ghosh, Partha S.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewMuscular dystrophies are a heterogeneous group of inherited muscular disorders characterized by progressive muscle weakness and in many cases cardiac and respiratory muscle involvement. Historically, these disorders are considered incurable with grave prognoses. The genes responsible for most muscular dystrophies are known, and ear...
Troy, Elizabeth Yonker, Marcy
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewPediatric migraine is common, and appropriate abortive treatment is important to limit impact on school performance and mental health. This review will describe the latest evidence for abortive treatment in the emergency department and inpatient settings.Recent FindingsIt is recognized that a protocol for emergency department treat...
