Joshi, Shivang G. Mechtler, Laszlo L.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewHigh altitude headache is a common neurological symptom that is associated with ascent to high altitude. It is classified by the International Classification of Headache Disorders, 3rd Edition (ICHD-3) as a disorder of homeostasis. In this article, we review recent clinical and insights into the pathophysiological mechanisms of hig...
Bodensteiner, John B.
Published in
Current Neurology and Neuroscience Reports
Purpose of reviewThis review is to delineate the neurological complications seen in patients with achondroplasia.Recent findingsAs the understanding of the genetics of this disorder has advanced, the possibility of targets for intervention which might modify the development and management of the neurological complications of this disease may be ide...
Troxell, Regina M. Christy, Alison
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewPediatric central nervous system demyelinating diseases include multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and acute disseminated encephalomyelitis (ADEM). As diagnostic criteria become more inclusive, the risk of misdiagnosis of atypical demyelinating diseases of rheumatologic, infectious, and autoimm...
Shaban, Amir Leira, Enrique C.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewSystemic lupus erythematosus (SLE) is commonly associated with neurological manifestations. Rapid recognition and treatment of these complications may improve outcomes. In this article, we review the neurological conditions associated with SLE, their diagnosis and management strategies.Recent FindingsRecent meta-analysis showed tha...
Silverman, Hannah E. Goldman, Jill S. Huey, Edward D.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewTo present recent findings on the links between the C9orf72 expansion and psychiatric impairment.Recent FindingsRepeat hexanucleotide expansions in the C9orf72 gene are a cause of familial frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), and the mixed phenotype, FTD-ALS. Symptomatic expansion carriers display hig...
Anand, Pria Chwalisz, Bart K.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewIn recent years, literature on neuroinflammatory disorders has dramatically expanded, as have options for treatment. However, few reviews have focused on skull-based manifestations of inflammatory disorders.Recent FindingsHere, we review the clinical manifestations, etiologies, diagnostic workup, and treatment of both systemic and ...
Tajfirouz, Deena A. Bhatti, M. Tariq Chen, John J.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewAntibodies against myelin oligodendrocyte glycoprotein (MOG) are associated with a unique acquired central nervous system demyelinating disease—termed MOG-IgG-associated disorder (MOGAD)—which has a variety of clinical manifestations, including optic neuritis, transverse myelitis, acute disseminating encephalomyelitis, and brainste...
Miller, Kristin L. Trifan, Gabriela Testai, Fernando D.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewThe goal of this chapter is to educate clinicians on the neurologic manifestations of certain nutritional deficiencies in order to promptly identify and appropriately treat these patients.Recent FindingsMany vitamin and nutritional deficiencies have been described dating back to the early days of neurology and medicine. Some are ve...
Farhad, Khosro
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewSmall fiber neuropathy (SFN) could cause significant morbidity due to neuropathic pain and autonomic dysfunction. SFN is underdiagnosed and the knowledge on the condition is limited among general public and health care professionals. This review is intended to enhance the understanding of SFN symptoms, causes, diagnostic tools, and...
Chung, David Y. Olson, DaiWai M. John, Sayona Mohamed, Wazim Kumar, Monisha A. Thompson, Bradford B. Rordorf, Guy A.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewThe optimal management of external ventricular drains (EVD) in the setting of acute brain injury remains controversial. Therefore, we sought to determine whether there are optimal management approaches based on the current evidence.Recent FindingsWe identified 2 recent retrospective studies on the management of EVDs after subarachn...
