Valdovinos, B. Y. Modica, J. S. Schneider, R. B.
Published in
Current Neurology and Neuroscience Reports
Purpose of Review The COVID-19 pandemic has dramatically affected the health and well-being of individuals with movement disorders. This manuscript reviews these effects, discusses pandemic-related changes in clinical care and research, and suggests improvements to care and research models. Recent Findings During the on-going COVID-19 pandemic, ind...
Frey, Jessica Malaty, Irene A.
Published in
Current Neurology and Neuroscience Reports
Purpose of Review This study aims to examine the treatments currently available for Tourette syndrome (TS) and to discuss evolving therapies, spanning behavioral, pharmacologic, complementary and alternative medicine, and neuromodulation approaches. Recent Findings Behavioral therapies have undergone several modifications to improve accessibility, ...
Pellinen, Jacob Holmes, Manisha Gupte
Published in
Current Neurology and Neuroscience Reports
Purpose of Review Seizures, including status epilepticus, have been reported in association with acute COVID-19 infection. People with epilepsy (PWE) have suffered from seizure exacerbations during the pandemic. This article reviews the data for clinical and electrographic seizures associated with COVID-19, technical EEG considerations for reducing...
Manivannan, S Wales, E Zaben, M
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewTraumatic brain injury (TBI) is amongst the leading causes of mortality and morbidity worldwide. However, several pharmacological strategies in the clinical setting remain unsuccessful. Mounting evidence implicates High Mobility Group Box protein 1 (HMGB1) as a unique alternative target following brain injury. Herein, we discuss cu...
Lee, Eudocia Q.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewTo review the neurologic complications of systemic anti-cancer therapies and radiation therapy.Recent FindingsAlthough many of the newer systemic therapies have more favorable side effect profiles than traditional cytotoxic chemotherapy, neurotoxicity has been seen with some of newer targeted therapies, immunotherapy, and T cell en...
Leddy, John J. Haider, Mohammad Nadir Noble, James M. Rieger, Brian Flanagan, Steven McPherson, Jacob I. Shubin-Stein, Kenneth Saleem, Ghazala T. Corsaro, Louis Willer, Barry
...
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewConcussion is a complex injury that may present as a variety of clinical profiles, which can overlap and reinforce one another. This review summarizes the medical management of patients with concussion and persistent post-concussive symptoms (PPCS).Recent FindingsManagement of concussion and PPCS relies on identifying underlying sy...
Perez, Alejandro Huse, Jason T.
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewThe upcoming 2021 World Health Organization (WHO) Classification of Tumours of the Central Nervous System will feature numerous changes in classification, diagnostic criteria, nomenclature, and grading of diffuse gliomas. This article reviews these changes and the clinical and molecular findings underlying them.Recent FindingsSince...
Mograbi, Daniel C. Huntley, Jonathan Critchley, Hugo
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewSelf-awareness, the capacity of becoming the object of one’s own awareness, has been a frontier of knowledge, but only recently scientific approaches to the theme have advanced. Self-awareness has important clinical implications, and a finer understanding of this concept may improve the clinical management of people with dementia. ...
Leddy, John J. Haider, Mohammad Nadir Noble, James M. Rieger, Brian Flanagan, Steven McPherson, Jacob I. Shubin-Stein, Kenneth Saleem, Ghazala T. Corsaro, Louis Willer, Barry
...
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewConcussion produces a variety of signs and symptoms. Most patients recover within 2–4 weeks, but a significant minority experiences persistent post-concussive symptoms (PPCS), some of which may be from associated cervical or persistent neurologic sub-system (e.g., vestibular) dysfunction. This review provides evidence-based informa...
Balestrini, Simona Guerrini, Renzo Sisodiya, Sanjay M.
Published in
Current Neurology and Neuroscience Reports
PurposeIn this descriptive review, we describe current models of transition in rare and complex epilepsy syndromes and propose alternative approaches for more holistic management based on disease biology.Recent FindingsPreviously published guidance and recommendations on transition strategies in individuals with epilepsy have not been systematicall...
