Published in Current Biology
Almeida et al. show that fusion of synaptic vesicles along axons in the developing zebrafish spinal cord is as frequent as at presynaptic terminals in some neuronal subtypes. In these neurons, axonal vesicular fusion is promoted by myelination and in turn consolidates sheath formation and growth.
Published in Current Biology
Multivesicular bodies (MVBs) are complex organelles harboring internal vesicles. Using a chemically controlled system, Perrin et al. visualize a part of these internal vesicles fusing back to the limiting membrane. This process of retrofusion exists in equilibrium with lysosomal degradation and exosome release and is inhibited by antiviral proteins...
Published in Current Biology
Kaljević et al. study non-binary proliferation in the predatory bacterium Bdellovibrio bacteriovorus . Examination of the spatiotemporal dynamics of its DNA throughout the cell cycle reveals that, as the predator elongates, concomitant rounds of replication and segregation generate chromosome copies for more than two daughter cells.
Published in Current Biology
Bartoszek et al. showed that ongoing habenular activity is driven by the ancestral homologs of amygdala (Dm) and hippocampus (Dl) in zebrafish forebrain. Activating Dm and Dl recruits a partially overlapping set of habenular neurons. Odor stimulation modulates the ongoing activity and communication between forebrain networks and the habenula.
Published in Current Biology
McKelvey et al. find that courting male D. melanogaster abdominal tremulations signal via substrate-borne, not air-borne, vibrations. These vibrations propagate through natural food substrates, promoting female immobility. Neurons and their mechanically gated ion channels within the leg fCHO mediate female response to the vibrations.
Published in Current biology : CB
Published in Current biology : CB
Published in Current Biology
Cave sediments preserve ancient DNA for thousands of years. Gelabert et al. retrieve human and mammalian nuclear and mitochondrial environmental “shotgun” genomes from a single 25,000-year-old sediment sample from Satsurblia cave. Their results provide insights into the population genetic histories of three mammalian species.
Published in Current Biology
Jacob et al. show that prior experience of an odor can inhibit the retrieval of a newly formed memory for that same odor. Odor pre-exposure forms a labile mushroom body-dependent aversive memory that competes with expression of new learning if the context is appropriate. This study explains how a retrieval defect can underlie latent inhibition.
Published in Current Biology
Ye et al. demonstrate that phytohormone cytokinin and four downstream LATERAL ORGAN BOUNDARIES DOMAIN (LBD) family of transcription factors promote the transition from primary to secondary growth in Arabidopsis root. LBDs negatively feed back to cytokinin signaling to keep secondary growth in balance.
