Published in Current Biology
Chromosome segregation requires attachments between kinetochores and microtubules. In budding yeast, the kinetochore complex Dam1 oligomerizes around microtubules to facilitate this connection. Gutierrez et al. show that the cell-cycle kinase Cdk1 phosphorylates the Dam1 complex to strengthen kinetochore-microtubule attachments during mitosis.
Published in Current Biology
Interview with Geoff Gadd, who studies the geoactive properties of micro-organisms, with a primary focus on fungi, at the University of Dundee.
Published in Current biology : CB
As environmental scientists working in countries whose COVID-linked deaths already exceed their military casualties from all campaigns since 1945, we believe there are significant messages from the handling of this horrific disease for efforts addressing the enormous challenges posed by the ongoing extinction and climate emergencies. Copyright © 20...
Published in Current Biology
Interview with Cat Hobaiter, who studies the evolution of communication, cognition and social behaviour in apes at the University of St Andrews and through field studies in the Budongo Forest in Uganda.
Published in Current Biology
Gong and colleagues analyse the state of wildlife management in China and make suggestions for better integration of management efforts.
Published in Current Biology
Marin et al. use connectomics and genetics for comprehensive identification of temperature and humidity sensory neurons in the Drosophila brain. They reconstruct all projections to higher brain areas and select higher-order targets, including the mushroom body lateral accessory calyx, linking thermosensation to memory and the circadian clock.
Published in Current Biology
Otto et al. use electron microscope resolution connectomics to describe the structure and organization of neurons providing synaptic input to functionally discrete subtypes of dopaminergic neurons. The nanoscale anatomy reveals further anatomical and functional specialization of dopaminergic neurons, which is confirmed with behavioral experiments.
Published in Current Biology
Bates, Schlegel et al. report the first complete part list of second-order neurons in an adult arthropod olfactory system. They show that these neurons are stereotyped across hemispheres and reveal their hierarchical interconnectivity and how they connect to third-order targets and memory-related neurons.
Published in Current Biology
In this Essay, Genzel et al. make the case for animal research in light of the COVID-19 pandemic.
Published in Current Biology
Ellison et al. show that the pore-forming toxin Lysenin can be used as a reporter for detecting sphingomyelin in the cytosolic leaflet of cellular membranes. The breakout of Gram-negative bacteria from vacuoles into the host cytosol follows a precisely choreographed process in which sphingomyelin exposure precedes catastrophic membrane damage.
