Published in Current Allergy and Asthma Reports
Purpose of Review At the juncture of the COVID-19 pandemic, the world is currently in an early phase of collecting clinical data and reports of its skin manifestations, and its pathophysiology is still highly conjectural. We reviewed cutaneous manifestations associated with COVID-19 in the pediatric age group. Recent Findings Children infected by S...
Published in Current Allergy and Asthma Reports
Purpose of ReviewThe aim of this systematic review is to present the proposed theories of pathogenesis for idiopathic anaphylaxis (IA), to discuss its classification, its diagnostic approach, and management.Recent FindingsIA represents a major diagnostic challenge and is diagnosed when excluding the possible identifiable triggers of anaphylaxis. Th...
Published in Current Allergy and Asthma Reports
Purpose of ReviewThe coronavirus disease 2019 (COVID-19) has challenged healthcare system capacities and safety for health care workers, reshaping doctor-patient interaction favoring e-Health or telemedicine. The pandemic situation may make difficult to prioritize patients with allergies diseases (AD), face-to-face evaluation, and moreover concern ...
Published in Current Allergy and Asthma Reports
Purpose of ReviewCystic fibrosis (CF) is a multisystem, autosomal recessive disease that leads to progressive loss of lung function. Respiratory symptoms for both CF and asthma include cough, wheezing, and dyspnea. There is debate within the CF community on how to best define and distinguish CF-asthma overlap syndrome (CFAOS) from asthma-like featu...
Published in Current Allergy and Asthma Reports
Purpose of ReviewThe purpose of this review is to provide a framework to distinguish Blau syndrome/Early Onset Sarcoidosis and Sarcoidosis clinically. We also discuss relevant differences in genetics, pathogenesis, and management of these diseases.Recent FindingsBlau syndrome and Sarcoidosis share the characteristic histologic finding of noncaseati...
Published in Current Allergy and Asthma Reports
Purpose of ReviewTo provide an overview of the prevalence and clinical manifestation of non-specific lipid transfer proteins (LTP)-mediated allergies outside the Mediterranean area and to address potential reasons for the different geographical significance of LTP-driven allergies.Recent FindingsLTPs are major allergens in the Mediterranean area, w...
Published in Current Allergy and Asthma Reports
Purpose of ReviewChemosensory dysfunction in the patients with COVID-19 has been reported frequently in the studies from different regions of the world. However, the prevalence of smell and/or taste disorders presents significant ethnic and geographic variability. In addition, the pathogenesis of chemosensory dysfunction remains unclarified.Recent ...
Published in Current Allergy and Asthma Reports
Purpose of ReviewTold from the viewpoint of rheumatologists, this review tells the story of hydroxychloroquine and its swift ascent to become a household name as a therapeutic strategy against the novel SARS-CoV-2 virus. This review describes the history, mechanisms, pharmacokinetics, therapeutic applications, and safety profile of hydroxychloroqui...
Published in Current Allergy and Asthma Reports
Purpose of ReviewThe goal of the paper is to review the epidemiology, pathogenesis, diagnosis, and manifestations of perioperative anaphylaxis (POA). We seek to review the most common culprits of POA and different diagnostic modalities for evaluation.Recent FindingsSpecific IgE testing has a limited role in POA evaluation due to lack of widespread ...
Published in Current Allergy and Asthma Reports
Purpose of ReviewAtopic dermatitis (AD) and allergic asthma are complex disorders with significant public health burden. This review provides an overview of the recent developments on Mas-related G protein-coupled receptor-X2 (MRGPRX2; mouse counterpart MrgprB2) as a potential candidate to target neuro-immune interaction in AD and allergic asthma.R...
