Published in Current Allergy and Asthma Reports
Purpose of ReviewThis review summarizes the latest information on the appropriate identification, evaluation, and treatment of patients with nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NSAID-ERD), also known as aspirin-exacerbated respiratory disease (AERD). Within the framework of our understanding of the underlyin...
Published in Current Allergy and Asthma Reports
Purpose of ReviewBronchial asthma is a common respiratory disease induced by immune imbalance, characterized by chronic non-specific airway inflammation and airway hyperresponsiveness (AHR). Many factors induce asthma, among which respiratory infection is the important cause. In this review, we discuss how respiratory microbes participate in the oc...
Published in Current Allergy and Asthma Reports
Purpose of ReviewFocusing on the strict relationship between house dust mites and crustaceans from the allergenic point of view.Recent FindingsThe well-known tropomyosin was considered for years as the cross-reacting allergen between shrimp and house dust mites. In the last few years, several allergens not only in shrimps but also in house dust mit...
Published in Current Allergy and Asthma Reports
Purpose of ReviewIt is well known that combination of sensitization and exposure to inhaled environmental allergens is related to both the development and elicitation of symptoms of asthma and that avoidance of allergens would exert beneficial effects in the prevention and control of the disease. Other important factors include the relevance of oth...
Published in Current Allergy and Asthma Reports
Purpose of ReviewTo improve our appreciation of the burden of chronic rhinosinusitis (CRS) and to understand better how to ease that burden.Recent FindingsThe burden of CRS is high. At an individual level, this burden is due to rhinologic symptoms as well as more systemic symptoms. At a societal level, the indirect costs of CRS, mostly due to reduc...
Published in Current Allergy and Asthma Reports
Purpose of ReviewIn recent decades, food allergy has become an increasing concern for families, clinicians, and policymakers. This review aims to summarize what is currently known about the epidemiology and population-level burden of IgE-mediated food allergy, including its effects on quality of life.Recent FindingsPrevalence surveys, healthcare ut...
Published in Current Allergy and Asthma Reports
Purpose of ReviewUsing the WHO Conceptual Framework for Action on the Social Determinants of Health, this review provides a discussion of recent epidemiologic, mechanistic, and intervention studies of structural and social determinants of health and asthma outcomes covering the period from 2014 to 2019.Recent FindingsA majority of studies and inter...
Published in Current Allergy and Asthma Reports
Purpose of ReviewProgestogen hypersensitivity (PH) is a condition which typically occurs in women in childbearing years with a spectrum of symptoms ranging from urticaria with or without angioedema, dermatitis to systemic anaphylaxis. Herein, a clinical case of PH is presented followed by a discussion on the evaluation, diagnosis, and management of...
Published in Current Allergy and Asthma Reports
Purpose of ReviewThe prevalence of food allergy is increasing. At the current time, there are no approved treatments for food allergy. Major limitations of immunotherapy are long treatment periods (months or years), frequent clinic visits, high costs, increased risk of adverse events during treatment, and lack of durability of desensitization. Addi...
Published in Current Allergy and Asthma Reports
Purpose of ReviewThis review is focused on the existing evidence for circadian control of innate and adaptive immune responses to provide a framework for evaluating the contributions of diurnal rhythms to control of infections and pathogenesis of disease.Recent FindingsCircadian rhythms driven by cell-autonomous biological clocks are central to inn...
