Davis, John P Wessells, Dustin A Moorman, J Randall
Published in
Critical care explorations
Coronavirus disease 2019 can lead to sudden and severe respiratory failure that mandates endotracheal intubation, a procedure much more safely performed under elective rather than emergency conditions. Early warning of rising risk of this event could benefit both patients and healthcare providers by reducing the high risk of emergency intubation. C...
van der Linden, Jan Almskog, Lou Liliequist, Andreas Grip, Jonathan Fux, Thomas Rysz, Susanne Ågren, Anna Oldner, Anders Ståhlberg, Marcus
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Critical care explorations
To determine the prevalence of thrombotic events, functional coagulation tests, inflammatory biomarkers, and antiphospholipid antibodies before and after enhanced anticoagulation in critically ill coronavirus disease 2019 patients. Retrospective. Tertiary intensive care unit. Two cross-sectional cohorts of ICU-treated coronavirus disease 2019 patie...
Gaulton, Timothy G Bellani, Giacomo Foti, Giuseppe Frazer, Michael J Fuchs, Barry D Cereda, Maurizio
Published in
Critical care explorations
Das, Anup Saffaran, Sina Chikhani, Marc Scott, Timothy E Laviola, Marianna Yehya, Nadir Laffey, John G Hardman, Jonathan G Bates, Declan G
Published in
Critical care explorations
Patients with coronavirus disease 2019 acute respiratory distress syndrome appear to present with at least two distinct phenotypes: severe hypoxemia with relatively well-preserved lung compliance and lung gas volumes (type 1) and a more conventional acute respiratory distress syndrome phenotype, displaying the typical characteristics of the "baby l...
Palazzuoli, Alberto Ruberto, Franco De Ferrari, Gaetano M Forleo, Giovanni Secco, Gioel G Ruocco, Gaetano M D'Ascenzo, Fabrizio Mojoli, Francesco Monticone, Silvia Paggi, Anita
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Published in
Critical care explorations
To describe patients according to the maximum degree of respiratory support received and report their inpatient mortality due to coronavirus disease 2019. Analysis of patients in the Coracle registry from February 22, 2020, to April 1, 2020. Hospitals in the Piedmont, Lombardy, Tuscany, and Lazio regions of Italy. Nine-hundred forty-eight patients ...
Keith, Philip D Scott, L Keith Weaver, Kathryn E Day, Matthew Choe, Carol Perkins, Linda Moyer, Louis Hays, Erin French, Marshall Hewitt, Kristi
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Published in
Critical care explorations
Sperotto, Francesca Cogo, Paola Amigoni, Angela Pettenazzo, Andrea Thiagarajan, Ravi R Polito, Angelo
Published in
Critical care explorations
Extracorporeal membrane oxygenation has been used to support children who fail to wean from cardiopulmonary bypass after pediatric cardiac surgery, but little is known about outcomes. We aimed to describe epidemiology and extracorporeal membrane oxygenation factors associated with inhospital mortality in these patients. Retrospective multicenter re...
Sadd, Corey Rowe, Timothy Nazeef, Moniba Kory, Pierre Sultan, Samir Faust, Hilary
Published in
Critical care explorations
Microvascular thrombosis contributes to acute respiratory distress syndrome pathophysiology and has been demonstrated in coronavirus disease 2019-associated acute respiratory distress syndrome. Clinical laboratory measurements of coagulation and disseminated intravascular coagulation, such as coagulation factor function, platelet count, and fibrino...
Czepiel, Kathryn S Lucas, Alexandra T Whalen, Michael J Mojica, James E
Published in
Critical care explorations
To present three patients with severe coronavirus disease 2019 infection who developed life-threatening hyperpyrexia while being treated with dexmedetomidine for sedation. Clinical records. Case report. Relevant clinical information. We describe three patients, a 60-year-old female, 43-year-old female, and 46-year-old male, who were hospitalized in...
Pollack, Charles V Jr Kurz, Michael A Hayward, Neil J
Published in
Critical care explorations
Current approaches to systemic antithrombotic therapy in support of extracorporeal membrane oxygenation are limited and are hampered by both thrombotic and hemorrhagic complications. An alternative approach is needed. Inhibition of coagulation factor XI/activated factor XI is an appealing pathway for antithrombotic support of extracorporeal membran...