Sprung, Charles L. Joynt, Gavin M. Christian, Michael D. Truog, Robert D. Rello, Jordi Nates, Joseph L.
Published in
Critical Care Medicine
Objectives: Coronavirus disease 2019 patients are currently overwhelming the world’s healthcare systems. This article provides practical guidance to front-line physicians forced to make critical rationing decisions. Data Sources: PubMed and Medline search for scientific literature, reviews, and guidance documents related to epidemic ICU triage incl...
Marini, John J. Gattinoni, Luciano
Published in
Critical Care Medicine
Objectives: To examine the potentially modifiable drivers that injure and heal the “baby lung” of acute respiratory distress syndrome and describe a rational clinical approach to favor benefit. Data Sources: Published experimental studies and clinical papers that address varied aspects of ventilator-induced lung injury pathogenesis and its conseque...
Zou, Xiaojing Li, Shusheng Fang, Minghao Hu, Ming Bian, Yi Ling, Jianmin Yu, Shanshan Jing, Liang Li, Donghui Huang, Jiao
...
Published in
Critical care medicine
Coronavirus disease 2019 has emerged as a major global health threat with a great number of deaths in China. We aimed to assess the association between Acute Physiology and Chronic Health Evaluation II score and hospital mortality in patients with coronavirus disease 2019, and to compare the predictive ability of Acute Physiology and Chronic Health...
Mauri, Tommaso Spinelli, Elena Scotti, Eleonora Colussi, Giulia Basile, Maria Cristina Crotti, Stefania Tubiolo, Daniela Tagliabue, Paola Zanella, Alberto Grasselli, Giacomo
...
Published in
Critical Care Medicine
Severe cases of coronavirus disease 2019 develop the acute respiratory distress syndrome, requiring admission to the ICU. This study aimed to describe specific pathophysiological characteristics of acute respiratory distress syndrome from coronavirus disease 2019. Design: Prospective crossover physiologic study. Setting: ICU of a university-affilia...
Leisman, Daniel E. Harhay, Michael O. Lederer, David J. Abramson, Michael Adjei, Alex A. Bakker, Jan Ballas, Zuhair K. Barreiro, Esther Bell, Scott C. Bellomo, Rinaldo
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Published in
Critical Care Medicine
Prediction models aim to use available data to predict a health state or outcome that has not yet been observed. Prediction is primarily relevant to clinical practice, but is also used in research, and administration. While prediction modeling involves estimating the relationship between patient factors and outcomes, it is distinct from casual infe...
Kerckhoffs, Monika C. Senekal, Jannien van Dijk, Diederik Artigas, Antonio Butler, Jenie Michalsen, Andrej van Mol, Margo M. C. Moreno, Rui Pais da Silva, Filipa Picetti, Edoardo
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Published in
Critical Care Medicine
To develop a consensus framework that can guide the process of decision-making on continuing or limiting life-sustaining treatments in ICU patients, using evidence-based items, supported by caregivers, patients, and surrogate decision makers from multiple countries. Design: A three-round web-based international Delphi consensus study with a priori ...
O’Rourke, James Soták, Michal Curley, Gerard F. Doolan, Aoife Henlín, Tomáš Mullins, Gerard Tyll, Tomáš Omlie, William Ranieri, Marco V.
Published in
Critical Care Medicine
Maintaining diaphragm work using electrical stimulation during mechanical ventilation has been proposed to attenuate ventilator-induced diaphragm dysfunction. This study assessed the safety and feasibility of temporary percutaneous electrical phrenic nerve stimulation on user-specified inspiratory breaths while on mechanical ventilation. Design: Tw...
Kadri, Sameer S.
Published in
Critical Care Medicine
Alhazzani, Waleed Møller, Morten Hylander Arabi, Yaseen M. Loeb, Mark Gong, Michelle Ng Fan, Eddy Oczkowski, Simon Levy, Mitchell M. Derde, Lennie Dzierba, Amy
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Published in
Critical Care Medicine
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting thousands of people around the world. Urgent guidance for clinicians caring for the sickest of these patients is needed. Methods: We formed a panel of 36 experts from 12 countries. All pa...
Gao, Chang Wang, Yeming Gu, Xiaoying Shen, Xinghua Zhou, Daming Zhou, Shujun Huang, Jian-an Cao, Bin Guo, Qiang
Published in
Critical Care Medicine
To evaluate the prevalence of cardiac injury and its association with mortality in hospitalized patients infected with avian influenza A (H7N9) virus. Design: Retrospective cohort study. Setting: A total of 133 hospitals in 17 provinces, autonomous regions, and municipalities of mainland China that admitted influenza A (H7N9) virus–infected patient...
