Massol, Julien Simon-Tillaux, Noémie Tohme, Joanna Hariri, Geoffroy Dureau, Pauline Duceau, Baptiste Belin, Lisa Hajage, David De Rycke, Yann Charfeddine, Ahmed
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Published in
Critical Care
Background Retrospective cohorts have suggested that levosimendan may facilitate the weaning of veno-arterial extracorporeal membrane oxygenation (VA-ECMO). We therefore studied this clinical question by emulating a randomized trial with observational data. Methods All patients with refractory postcardiotomy cardiogenic shock and assisted with VA-E...
Pardo, Emmanuel Lescot, Thomas Preiser, Jean-Charles Massanet, Pablo Pons, Antoine Jaber, Samir Fraipont, Vincent Levesque, Eric Ichai, Carole Petit, Laurent
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Published in
Critical care (London, England)
Current guidelines suggest the introduction of early nutrition support within the first 48 h of admission to the intensive care unit (ICU) for patients who cannot eat. In that context, we aimed to describe nutrition practices in the ICU and study the association between the introduction of early nutrition support ( 3 days were consecutively include...
Contou, Damien Béduneau, Gaëtan Rabault, Charlotte Sonneville, Romain Marchalot, Antoine Coudroy, Rémi Roux, Damien Cour, Martin Massol, Julien Préau, Sébastien
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Published in
Critical Care
Background Neisseria meningitidis is the leading responsible bacterium of Purpura Fulminans (PF) accounting for two thirds of PF. Skin biopsy is a simple and minimally invasive exam allowing to perform skin culture and polymerase chain reaction (PCR) to detect Neisseria meningitidis . We aimed to assess the sensitivity of skin biopsy in adult patie...
Foucrier, Arnaud Dessalle, Thomas Tuffet, Sophie Federici, Laura Dahyot-Fizelier, Claire Barbier, François Pottecher, Julien Monsel, Antoine Hissem, Tarik Lefrant, Jean-Yves
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Published in
Critical care (London, England)
The optimal treatment duration and the nature of regimen of antibiotics (monotherapy or combination therapy) for Pseudomonas aeruginosa ventilator‑associated pneumonia (PA-VAP) remain debated. The aim of this study was to evaluate whether a combination antibiotic therapy is superior to a monotherapy in patients with PA-VAP in terms of reduction in ...
Trøseid, Marius Arribas, José R. Assoumou, Lambert Holten, Aleksander Rygh Poissy, Julien Terzić, Vida Mazzaferri, Fulvia Baño, Jesús Rodríguez Eustace, Joe Hites, Maya
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Published in
Critical Care
Background Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID, including vaccinated participants. Methods Bari-SolidAct is a phase-3, multicentre, randomised, double-blind, placebo-controlled trial, enrolling participants from June 3, 2021 to Mar...
Jabaudon, Matthieu Genevrier, Alexandra Jaber, Samir Windisch, Olivier Bulyez, Stéphanie Laterre, Pierre-François Escudier, Etienne Sossou, Achille Guerci, Philippe Bertrand, Pierre-Marie
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Published in
Critical Care
Background Findings from preclinical studies and one pilot clinical trial suggest potential benefits of epidural analgesia in acute pancreatitis. We aimed to assess the efficacy of thoracic epidural analgesia, in addition to usual care, in improving clinical outcomes of intensive care unit patients with acute pancreatitis. Methods A multicenter, op...
Bodinier, Maxime Monneret, Guillaume Casimir, Marie Fleurie, Aurore Conti, Filippo Venet, Fabienne Cazalis, Marie-Angélique Cerrato, Elisabeth Peronnet, Estelle Rimmelé, Thomas
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Published in
Critical Care
Background The development of stratification tools based on the assessment of circulating mRNA of genes involved in the immune response is constrained by the heterogeneity of septic patients. The aim of this study is to develop a transcriptomic score based on a pragmatic combination of immune-related genes detected with a prototype multiplex PCR to...
van Oosterhout, Sanne P. C. van der Niet, Anneke G. Abdo, W. Farid Boenink, Marianne Cherpanath, Thomas G. V. Epker, Jelle L. Kotsopoulos, Angela M. van Mook, Walther N. K. A. Sonneveld, Hans P. C. Volbeda, Meint
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Published in
Critical Care
Background The Netherlands introduced an opt-out donor system in 2020. While the default in (presumed) consent cases is donation, family involvement adds a crucial layer of influence when applying this default in clinical practice. We explored how clinicians discuss patients’ donor registrations of (presumed) consent in donor conversations in the f...
Wang, Shengfeng Liu, Jian Huang, Lingtong
Published in
Critical Care
Zhang, Qibing Zhang, Xiaodong Han, Chunrong You, Jiqin Zhao, Yunxia Xu, Rong Zhao, Shiyan Geng, Yan
Published in
Critical Care
