Rate control in atrial fibrillation using Landiolol is safe in critically ill Covid-19 patients
Published in Critical Care
Diaphragm echodensity in mechanically ventilated patients: a description of technique and outcomes
Published in Critical Care
Background Acute increases in muscle sonographic echodensity reflect muscle injury. Diaphragm echodensity has not been measured in mechanically ventilated patients. We undertook to develop a technique to characterize changes in diaphragm echodensity during mechanical ventilation and to assess whether these changes are correlated with prolonged mech...
Long-term outcome after intensive care for COVID-19: differences between men and women—a nationwide cohort study
Published in Critical Care
Background Questions remain about long-term outcome for COVID-19 patients in general, and differences between men and women in particular given the fact that men seem to suffer a more dramatic course of the disease. We therefore analysed outcome beyond 90 days in ICU patients with COVID-19, with special focus on differences between men and women. M...
Long-term health-related quality of life and burden of disease after intensive care: development of a patient-reported o...
Published in Critical Care
Background ICU survivorship includes a diverse burden of disease. Current questionnaires used for collecting information about health-related problems and their relation to quality of life lack detailed questions in several areas relevant to ICU survivors. Our aim was to construct a provisional questionnaire on health-related issues based on interv...
Closed-loop circuit for reduce oxygen waste on hollow-fiber oxygenators during extracorporeal technologies
Published in Critical Care
Predicting neurological outcome after out-of-hospital cardiac arrest with cumulative information; development and intern...
...Published in Critical Care
Background Prognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of i...
Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European inten...
...Published in Critical Care
Background Mortality rates for patients with ARDS remain high. We assessed temporal changes in the epidemiology and management of ARDS patients requiring invasive mechanical ventilation in European ICUs. We also investigated the association between ventilatory settings and outcome in these patients. Methods This was a post hoc analysis of two cohor...
Frailty status among older critically ill patients with severe acute kidney injury
Published in Critical Care
Background Frailty status among critically ill patients with acute kidney injury (AKI) is not well described despite its importance for prognostication and informed decision-making on life-sustaining therapies. In this study, we aim to describe the epidemiology of frailty in a cohort of older critically ill patients with severe AKI, the outcomes of...
Computed tomography assessment of PEEP-induced alveolar recruitment in patients with severe COVID-19 pneumonia
...Published in Critical Care
Background There is a paucity of data concerning the optimal ventilator management in patients with COVID-19 pneumonia; particularly, the optimal levels of positive-end expiratory pressure (PEEP) are unknown. We aimed to investigate the effects of two levels of PEEP on alveolar recruitment in critically ill patients with severe COVID-19 pneumonia. ...
Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak
...Published in Critical Care
Background Respiratory failure due to COVID-19 pneumonia is associated with high mortality and may overwhelm health care systems, due to the surge of patients requiring advanced respiratory support. Shortage of intensive care unit (ICU) beds required many patients to be treated outside the ICU despite severe gas exchange impairment. Helmet is an ef...
