Guillemin, G Boussin, F Dormont, D
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Comptes rendus des seances de la Societe de biologie et de ses filiales
We have developed protocols for the isolation, the culture and the immunocytochemical characterization of astrocytes from simian adult brains. We have obtained pure astrocyte cultures without contamination with other cells present in brain. No microglial cells, oligodendrocytes, neurons or fibroblasts were detected by specific staining in immunocyt...
Bellucci, S
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Autoimmune thrombocytopenias (or ITP) are due mainly to an increased platelet phagocytosis by macrophages, the platelets being sensitized by the presence of autoantibodies at their surface. However, recent studies have shown, as reported in this review, that a dysmegakaryocytopoiesis possibly occurs concomitantly to the peripheral destruction of pl...
Cacheux, V Delezoide, A L Vekemans, M
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Waardenburg syndrome is an autosomal dominant disorder characterised by sensorineural hearing loss, pigmentary abnormalities of iris, hair and skin and dystopia canthorum. The expression of clinical findings of Waardenburg syndrome is extremely variable. The potential sources of this variability include allelic variation, genetic heterogeneity, epi...
Spehner, V Aberlin, S Biichlé, S Seillès, E
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Comptes rendus des seances de la Societe de biologie et de ses filiales
In addition to their antibacterial properties, quinolones are capable of modulating the immune response. The aim of this paper was to study the effects of a new fluoro-4-quinolone on the respiratory burst. We evaluated the effects of marbofloxacin on the activation of peripheral phagocytes in non-infected bovines after a 5-day treatment. The immuno...
Mourey, F Pozzo, T
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Standing up from and sitting down to a chair are a challenging task for many elderly persons. The purpose of this study was to analyse the effects of ageing in kinematic features of each phase of motion. The study was performed on 7 young subjects (22.8 +/- 1.5 years) and 5 healthy elderly subjects (73.2 +/- 5.5 years). The kinematics of the moveme...
Papaxanthis, C Pozzo, T
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Arm movements in two directions (downward assisted by gravity and upward against gravity) with three different loads (no load 0.5 and 1 kg) were studied in six subjects. Movements of the arm were recorded using an optoelectronic (2 TV, 100 Hz) system which allowed the computer reconstruction of joint motion. Analyses focused upon finger kinematics ...
Petit, C Hoffmann, P Souchard, J P Nepveu, F Labidalle, S
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Until recently, nitric oxide (NO.) was considered as a toxic radical, but it appears now as an essential messenger implicated in a wide range of biological processes, including immune system, cardiovascular system, and nervous system. An aspect of NO. metabolism in vivo is the formation of a variety of high and low molecular weight nitrosothiols. S...
Aurias, A
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Microdeletions of 22q11.2 are associated with a wide range of congenital disorders involving structures derived from the third and fourth pharyngeal pouches. This observation suggests that one major gene playing a part in rhombencephalic neural crest cells migration is localized in this small genomic region. Seven new genes have already been mapped...
Pasini, A Michiels, F M Chappuis-Flament, S Geneste, O Rossel, M Fournier, L Feunteun, J Lenoir, G Schuffenecker, I Billaud, M
...
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Multiple endocrine neoplasia type 2 (MEN 2) is a cancer syndrome which comprises three related disorders, MEN type 2A (MEN 2A), type 2B (MEN 2B) and familial medullary thyroid carcinoma (FMTC), MEN 2A is characterized by the association of MTC, a tumour arising from thyroid C-cells, pheochromocytoma and parathyroid hyperplasia. In addition to the t...
Legreneur, P Morlon, B Van Hoecke, J
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Comptes rendus des seances de la Societe de biologie et de ses filiales
The main purpose of this study was to investigate the maximal isometric plantarflexion moment as a function of the triceps surae's length. As the gastrocnemius are bi-articular actuators, their respective lengths were modified by variations of the ankle and knee joints angles. The mechanical results agreed ones previously published in the literatur...