Cheng, Yuancun Zheng, Xiaoyi Zhang, Liying Zhao, Jiulong Hu, Lianghao Wang, Shige
Published in
Colloids and surfaces. B, Biointerfaces
The degradation of extracellular matrix (ECM) to increase drug permeability is an attractive approach to enhancing pancreatic cancer therapy efficiency. Herein, polypyrrole nanoparticles (PPy NPs) were prepared by a template-guided chemical oxidation method. These PPy NPs with abundant surface pores were used to load the anticancer drug doxorubicin...
Li, Wenlong Cai, Jingfeng Zhou, Wenbo Zhao, Xueqin Wang, Miao Zhou, Xi Ren, Lei
Published in
Colloids and surfaces. B, Biointerfaces
The development of wound dressings with antibacterial activities and simultaneous pro-healing functions are always urgent in treating bacterial wound infection. Herein, a novel multifunctional self-healing hydrogel was designed and prepared by crosslinking quaternary ammonium/boronic acid modified poly(aspartic acid) and poly (vinyl alcohol) polyme...
Zhang, Yaqian Li, Meiting Zhang, Xiaoge Zhang, Peng Liu, Zhuoyin Feng, Miao Ren, Guangli Liu, Jie
Published in
Colloids and surfaces. B, Biointerfaces
Chemodynamic therapy (CDT), which takes advantages of CDT agents to selectively induce tumor cells apoptosis via Fenton or Fenton-like reactions, is considered to have great potential for tumor-specific treatment. However, the therapeutic outcome of CDT still faces the challenges of the lack of efficient CDT agents and insufficient supply of endoge...
Sheykhisarem, Roya Dehghani, Hossein
Published in
Colloids and surfaces. B, Biointerfaces
Here, a pH-sensitive biocompatible nanocarrier system is synthesized by the combination of Bi2MoO6 nanoparticles, NH2-graphene oxide (GO), and polyethylene glycol (PEG) for loading and delivery of daunorubicin (DNR) into breast cancer cells. DNR is loaded onto the nanocarrier surface via covalent bonding, exhibiting pH-sensitive behavior so that in...
Neamtu, Andrei Mocci, Francesca Laaksonen, Aatto Barroso da Silva, Fernando L
Published in
Colloids and surfaces. B, Biointerfaces
A highly efficient and robust multiple scales in silico protocol, consisting of atomistic Molecular Dynamics (MD), coarse-grain (CG) MD, and constant-pH CG Monte Carlo (MC), has been developed and used to study the binding affinities of selected antigen-binding fragments of the monoclonal antibody (mAbs) CR3022 and several of its here optimized ver...
Wu, Yue Zhang, Huihong Li, Jianwei Wang, Zhonghua Jiang, Ying
Published in
Colloids and surfaces. B, Biointerfaces
Soil invertase plays important role in the enzyme-driven degradation of soil organic carbon, and influenced by the adsorption of minerals or clays. We studied the adsorption effects of goethite, gibbsite and their organic complexes (with tannic acid) on invertase, aiming to explore the influence on the mobility and catalytic behavior of invertase. ...
Piscioneri, Antonella Morelli, Sabrina Ritacco, Tiziana Giocondo, Michele Peñaloza, Rafael Drioli, Enrico De Bartolo, Loredana
Published in
Colloids and surfaces. B, Biointerfaces
Biomaterial surface modification through the introduction of defined and repeated patterns of topography helps study cell behavior in response to defined geometrical cues. The lithographic molding technique is widely used for conferring biomaterial surface microscale cues and enhancing the performance of biomedical devices. In this work, different ...
Wang, Yuhui Ma, Shilong Liu, Xuanyu Wei, Yan Xu, Haofeng Liang, Ziwei Hu, Yinchun Lian, Xiaojie Huang, Di
Published in
Colloids and surfaces. B, Biointerfaces
Hepatocellular carcinoma (HCC) is one of the deadliest tumors in the world with a high rate of recurrence and metastasis. Therefore, the most pressing issue today is the development of new drugs, diagnostic and therapeutic approaches for effective cancer treatment. Cancer stem cells (CSCs) play a pivotal role in tumor recurrence, tumor resistance, ...
Nagase, Kenichi Okada, Akari Matsuda, Junnosuke Ichikawa, Daiju Hattori, Yutaka Kanazawa, Hideko
Published in
Colloids and surfaces. B, Biointerfaces
Adipose-derived mesenchymal stem cells (ADSCs) have beneficial effects in cell transplantation therapy; these cells are collected from adipose tissue using low-invasive methods. However, to prepare ADSCs for cell therapy, a cell separation method that neither involves modification of the cell surface nor causes loss of cell activity is needed. Here...
Pandey, Anurag Kumar Bankoti, Kamakshi Nath, Tapan Kumar Dhara, Santanu
Published in
Colloids and surfaces. B, Biointerfaces
In recent times, carbon dots (CDs) are emerging for numerous interdisciplinary applications by modulating their inherent chemical functionality during or post-synthesis modification. The current study reports the hydrothermal synthesis of polyvinylpyrrolidone K-30 (PVP) passivated clove bud-derived carbon dots (PPCCDs) for multifaceted applications...
