Phillips, Bradley G Wang, Ye Ambati, Suresh Ma, Ping Meagher, Richard B
Published in
Clinical immunology (Orlando, Fla.)
Obstructive Sleep Apnea (OSA) damages the health of 35% of adult Americans. Disordered sleep results in increased risk of several autoimmune disorders, but the molecular links to autoimmunity are poorly understood. Herein, we identified four cytokines associated with autoimmune disease, whose median serum levels were significantly different for OSA...
Wildermann, Christine Alosaimi, Mohammed Liebenehm, Sophie Jacobsen, Eva-Maria Barth, Thomas F E Möller, Peter Debatin, Klaus-Michael Schulz, Ansgar Sirin, Mehtap Abosoudah, Ibraheem F
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Published in
Clinical immunology (Orlando, Fla.)
Complete remission from recurrent EBV-positive lymphoma is not mandatory before HSCT to achieve long-term cure in a patient suffering from a recently described immunodeficiency affecting the T-cell coactivation molecule 4-1BB. Copyright © 2020 Elsevier Inc. All rights reserved.
Campos-López, Bertha Meza-Meza, Mónica R Parra-Rojas, Isela Ruiz-Ballesteros, Adolfo I Vizmanos-Lamotte, Barbara Muñoz-Valle, José Francisco Montoya-Buelna, Margarita Cerpa-Cruz, Sergio Bernal-Hernández, Luis E De la Cruz-Mosso, Ulises
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Published in
Clinical immunology (Orlando, Fla.)
Cardiometabolic status is a key factor in mortality by cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). This study evaluated the association of cardiometabolic risk status with clinical activity and damage in SLE patients. A cross-sectional study was conducted in 158 SLE patients and 123 healthy subjects (HS). Anthropometry, gluc...
Wang, Hui Zhou, Junjie Li, Jun Geng, Yiqun Meng, Pei Ma, Changchun Zhu, Ziqi Zhang, Weifeng Hong, Liangli Quan, Yan
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Published in
Clinical immunology (Orlando, Fla.)
To evaluate the occurrence, abundance, distribution, nature and clinical significance of multinucleated giant cell (MGC) in esophageal cancer. MGCs were examined with conventional pathology, immunohistochemistry and immunofluorescence in 107 esophageal cancer tissues. The findings were correlated to pathological diagnosis and clinical behavior of t...
Yao, Ying Zia, Asima Neumann, Ralf Stefan Pavlovic, Milena Balaban, Gabriel Lundin, Knut E A Sandve, Geir Kjetil Qiao, Shuo-Wang
Published in
Clinical immunology (Orlando, Fla.)
An individual's T cell repertoire is skewed towards some specificities as a result of past antigen exposure and subsequent clonal expansion. Identifying T cell receptor signatures associated with a disease is challenging due to the overall complexity of antigens and polymorphic HLA allotypes. In celiac disease, the antigen epitopes are well charact...
Lougaris, Vassilios Malagola, Michele Baronio, Manuela Morello, Enrico Gazzurelli, Luisa Benvenuto, Alessio Palumbo, Laura Moratto, Daniele Girelli, Maria Federica Chiarini, Marcho
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Published in
Clinical immunology (Orlando, Fla.)
Gasmi, Amin Tippairote, Torsak Mujawdiya, Pavan Kumar Peana, Massimiliano Menzel, Alain Dadar, Maryam Gasmi Benahmed, Asma Bjørklund, Geir
Published in
Clinical immunology (Orlando, Fla.)
COVID-19 rapidly turned to a global pandemic posing lethal threats to overwhelming health care capabilities, despite its relatively low mortality rate. The clinical respiratory symptoms include dry cough, fever, anosmia, breathing difficulties, and subsequent respiratory failure. No known cure is available for COVID-19. Apart from the anti-viral st...
Geng, Manman Xu, Ke Meng, Liesu Xu, Jing Jiang, Congshan Guo, Yuanxu Ren, Xiaoyu Li, Xiaowei Peng, Yizhao Wang, Si
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Published in
Clinical immunology (Orlando, Fla.)
Endoplasmic reticulum (ER) stress associated proteins contribute to the pathogenesis of rheumatoid arthritis (RA) through affecting synoviocyte proliferation and proinflammatory cytokine production. The role of DERL3, an ER-associated degradation component, in joint inflammation of RA was explored. Synovial tissues from RA and osteoarthritis (OA) p...
Toussi, Atrin Maverakis, Natalia Le, Stephanie T Sarkar, Soumajyoti Raychaudhuri, Smriti K Raychaudhuri, Siba P
Published in
Clinical immunology (Orlando, Fla.)
Psoriatic arthritis (PsA) is a large volume of our clinical practice and its management can be challenging. Traditional DMARDs have been used over last six decades and observational studies have substantiated an effective use of many of these drugs. However, in last two decades use of anti-TNF agents has brought a new dimension in treatment of PsA ...
Salonen, Johanna Lampela, Henri Keskitalo, Eerika Vähänikkilä, Hannu Purokivi, Minna Kaarteenaho, Riitta
Published in
Clinical immunology (Orlando, Fla.)
BAL cell differential counts of 133 therapy naive ILD patients and 43 patients during acute exacerbation of ILD (AE-ILD) were retrospectively evaluated. In the 20 patients who underwent BAL both at baseline and during an AE-ILD, there was an increase in neutrophils but a decrease in macrophages and eosinophils in the BAL obtained during AE-ILD. A d...
