De Michieli, Laura Ola, Olatunde Knott, Jonathan D Akula, Ashok Mehta, Ramila A Hodge, David O Dworak, Marshall Yang, Eric H Gharacholou, Michael Singh, Gurpreet
...
Published in
Clinical chemistry
Limited data exist on high-sensitivity cardiac troponin (hs-cTn) for risk-stratification in COVID-19. We conducted a multicenter, retrospective, observational, US-based study of COVID-19 patients undergoing hs-cTnT. Outcomes included short-term mortality (in-hospital and 30-days post-discharge) and a composite of major adverse events, including res...
Echouffo-Tcheugui, Justin B. Daya, Natalie Matsushita, Kunihiro Wang, Dan Ndumele, Chiadi E. Al Rifai, Mahmoud Hoogeveen, Ron C. Ballantyne, Christie M. Selvin, Elizabeth
Published in
Clinical chemistry
INTRODUCTION: Laboratory studies suggest an involvement of growth differentiation factor 15 (GDF-15) in metabolic dysregulation. However, the utility of GDF-15 for assessing risk of cardiometabolic outcomes has not been rigorously examined among older adults. METHODS: We conducted a cross-sectional analysis of older adults who attended visit 6 (201...
Pho, Nam Manrai, Arjun K Leppert, John T Chertow, Glenn M Ioannidis, John P A Patel, Chirag J
Published in
Clinical chemistry
Physicians sometimes consider whether or not to perform diagnostic testing in healthy people, but it is unknown whether nonextreme values of diagnostic tests typically encountered in such populations have any predictive ability, in particular for risk of death. The goal of this study was to quantify the associations among population reference inter...
Tan, It-Koon
Published in
Clinical chemistry
Kataria, Yachana
Published in
Clinical chemistry
Marcovina, Santica M Clouet-Foraison, Noémie Koschinsky, Marlys L Lowenthal, Mark S Orquillas, Allen Boffa, Michael B Hoofnagle, Andrew N Vaisar, Tomáš
Published in
Clinical chemistry
Use of lipoprotein(a) concentrations for identification of individuals at high risk of cardiovascular diseases is hampered by the size polymorphism of apolipoprotein(a), which strongly impacts immunochemical methods, resulting in discordant values. The availability of a reference method with accurate values expressed in SI units is essential for im...
Fortuny, Lisandro R Cabler, Stephanie S Hunstad, David A Yarbrough, Melanie L
Published in
Clinical chemistry
Duchon, Jennifer M
Published in
Clinical chemistry
Rappold, Brian A
Published in
Clinical chemistry
Giménez-Capitán, Ana Bracht, Jillian García, Juan José Jordana-Ariza, Núria García, Beatriz Garzón, Mónica Mayo-de-Las-Casas, Clara Viteri-Ramirez, Santiago Martinez-Bueno, Alejandro Aguilar, Andrés
...
Published in
Clinical chemistry
With the advent of precision oncology, liquid biopsies are quickly gaining acceptance in the clinical setting. However, in some cases, the amount of DNA isolated is insufficient for Next-Generation Sequencing (NGS) analysis. The nCounter platform could be an alternative, but it has never been explored for detection of clinically relevant alteration...
