Blood, Alexander J Fischer, Christina M Fera, Liliana E MacLean, Taylor E Smith, Katelyn V Dunning, Jacqueline R Bosque-Hamilton, Joshua W Aronson, Samuel J Gaziano, Thomas A MacRae, Calum A
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Published in
Clinical cardiology
Although optimal pharmacological therapy for heart failure with reduced ejection fraction (HFrEF) is carefully scripted by treatment guidelines, many eligible patients are not treated with guideline-directed medical therapy (GDMT) in clinical practice. We designed a strategy for remote optimization of GDMT on a population scale in patients with HFr...
Long, Songbing Xi, Yutao Gao, Lianjun Chen, Qi Cheng, Jie Yang, Yanzong Xia, Yunlong Yin, Xiaomeng
Published in
Clinical cardiology
Catheter ablation (CA) for atrial fibrillation (AF) in heart failure (HF) patients reduced the mortality but may increase complications and raise the safety concern. CA for AF in HF patients may not increase the complications vs medical treatment, and it may reduce hospitalizations and mortality and improve heart function. Three groups of AF patien...
Åkerblom, Axel James, Stefan K Lakic, Tatevik G Becker, Richard C Cannon, Christopher P Steg, Philippe G Himmelmann, Anders Katus, Hugo A Storey, Robert F Wallentin, Lars
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Published in
Clinical cardiology
We aimed to assess associations between circulating IL-18 concentrations and cardiovascular outcomes in patients with acute coronary syndromes (ACS). Plasma IL-18 concentrations were measured at admission, discharge, 1 month, and 6 months in patients with ACS in the PLATelet inhibition and patient Outcomes (PLATO) trial. Associations with outcomes ...
Cunningham, Jonathan W Sun, Jie-Lena Mc Causland, Finnian R Ly, Samantha Anstrom, Kevin J Lindenfeld, Joann Givertz, Michael M Stevenson, Lynne W Lakdawala, Neal K
Published in
Clinical cardiology
In patients hospitalized with acute heart failure (AHF), low urine sodium concentration (UNa ) after diuretic treatment may identify patients at risk for longer length of stay (LOS) and adverse events. We investigated the prognostic significance of 24-hour cumulative postdiuretic urine sodium concentration in a multicenter clinical trial population...
Kostopoulou, Anna Zeljko, Hrvojka M Bogossian, Harilaos Ciudin, Radu Costa, Francisco Heijman, Jordi Kochhaeuser, Simon Manola, Sime Scherr, Daniel Sohal, Manav
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Published in
Clinical cardiology
Atrial fibrillation (AF) is the most common clinical arrhythmia and one of the major causes of stroke, heart failure, sudden death, and cardiovascular morbidity. Despite substantial advances in (interventional) rhythm control treatment during the last decade, anticoagulation for stroke prevention remains a major component of AF treatment. There are...
Pandozi, Claudio Lavalle, Carlo Russo, Maurizio Galeazzi, Marco Ficili, Sabina Malacrida, Maurizio Centurion Aznaran, Carlos Colivicchi, Furio
Published in
Clinical cardiology
Despite the technical improvements made in recent years, the overall long-term success rate of ventricular tachycardia (VT) ablation in patients with ischemic cardiomyopathy remains disappointing. This unsatisfactory situation has persisted even though several approaches to VT substrate ablation allow mapping and ablation of noninducible/nontolerat...
Wang, Guangqiang Zhao, Na Zhong, Shu Li, Jianping
Published in
Clinical cardiology
Little is known about the correlation between triggering factors, clinical characteristics, diagnosis, and prognosis of patients with type 2 myocardial infarction (T2MI). The triggers and features of T2MI are linked to its diagnosis and prognosis. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were follow...
Zheng, Zi-Heng Zeng, Xun Nie, Xiao-Ying Cheng, Yun-Jiu Liu, Jun Lin, Xiao-Xiong Yao, Hao Ji, Cheng-Cheng Chen, Xu-Miao Jun, Fan
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Published in
Clinical cardiology
Interleukin-1 (IL-1) played a role in the occurrence and development of atherosclerosis and cardiovascular events. However, the association between IL-1 blockage treatment and reducing of cardiovascular risk remains poorly defined. IL-1 blockage treatment reduce the risk and incidence rate of overall major adverse cardiovascular events (MACE), all-...
Cantillon, Daniel J Burkle, Alicia Kirkwood, Desiree Loy, Molly Amuthan, Ram Pengel, Shannon Tote, John Morris, William Houghtaling, Penny L Hamilton, Aaron C
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Published in
Clinical cardiology
Cardiac telemetry monitoring is widely utilized for a variety of clinical indications, yet indication-specific event rates for monitored patients are seldomly reported. High-risk hospitalized patients for clinical deterioration can be identified using standardized telemetry monitoring indications. Adjudicated data from events triggering emergency r...
Sun, Di Cao, Ye-Xuan Li, Sha Guo, Yuan-Lin Wu, Na-Qiong Gao, Ying Dong, Qiu-Ting Liu, Geng Dong, Qian Li, Jian-Jun
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Published in
Clinical cardiology
Previous studies have observed that high level of lipoprotein (a) [Lp(a)] was common in the phenotypic familial hypercholesterolemia (FH) and may explain part of the clinical diagnosis of FH. We aim to develop a modified model including Lp(a) and compare its diagnostic performance with Dutch Lipid Clinic Network (DLCN) criteria. Data of 10 449 indi...
