da Silveira, Matheus Pelinski da Silva Fagundes, Kimberly Kamila Bizuti, Matheus Ribeiro Starck, Édina Rossi, Renata Calciolari de Resende E Silva, Débora Tavares
Published in
Clinical and experimental medicine
Acute viral respiratory infections are the main infectious disease in the world. In 2020, a new disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus disease 2019 (COVID-19), became a global pandemic. The immune response to the virus depends on factors such as genetics, age and physical state, and its main inpu...
Sheng, Lingshuang Wang, Xiong Tang, Ning Meng, Fankai Huang, Liang Li, Dengju
Published in
Clinical and experimental medicine
With the outbreak of COVID-19 ongoing, this infectious disease has been posing a significant threat to public health. However, we are still relatively inexperienced on recognizing the clinical characteristics of severe COVID-19 and death cases. Therefore, we hereby collected and analyzed a total of 232 cases to illustrate the clinical characteristi...
Tentolouris, Anastasios Ntanasis-Stathopoulos, Ioannis Vlachakis, Panayotis K Tsilimigras, Diamantis I Gavriatopoulou, Maria Dimopoulos, Meletios A
Published in
Clinical and experimental medicine
Thousands of articles have been published regarding the coronavirus disease of 2019 (COVID-19). Most of them are not original research articles but reviews and editorials, and therefore, the absence of evidence-based guidelines has been evident. In parallel, the quality of manuscripts is questionable since the number of preprints has increased due ...
Bergamaschi, Gaetano de Andreis, Federica Borrelli Aronico, Nicola Lenti, Marco Vincenzo Barteselli, Chiara Merli, Stefania Pellegrino, Ivan Coppola, Luigi Cremonte, Elisa Maria Croce, Gabriele
...
Published in
Clinical and experimental medicine
COVID-19 patients typically present with lower airway disease, although involvement of other organ systems is usually the rule. Hematological manifestations such as thrombocytopenia and reduced lymphocyte and eosinophil numbers are highly prevalent in COVID-19 and have prognostic significance. Few data, however, are available about the prevalence a...
Baran, Munevver Ozturk, Fıgen Canoz, Ozlem Onder, Gozde Ozge Yay, Arzu
Published in
Clinical and experimental medicine
This study aimed to evaluate the biological and clinical significance of apelin-36 in breast cancer and to compare apelin-36 expression and apoptotic index in both breast tissue and metastatic lymph nodes in patients with invasive breast carcinoma. In this study, both tumor tissue and metastatic lymph nodes of the same patient were collected from 6...
Kan, Lian-Di Chen, Jie Huang, Yue-Ting Qiu, Yang Yu, Xin-Lu Fang, Hong-Mei Chen, Qin Li, Liu-Cheng
Published in
Clinical and experimental medicine
To evaluate the efficacy and economics of different proton pump inhibitors (PPIs) combined with bismuth quadruple regimens for Helicobacter pylori (Hp) eradication, a retrospective analysis method was used to collect Hp-positive patients who were treated with a bismuth-containing quadruple regimen (PPIs + amoxicillin + furazolidone + colloid pectin...
Lundh, Stefan Jung, In-Young Dimitri, Alexander Vora, Anish Melenhorst, J Joseph Jadlowsky, Julie K Fraietta, Joseph A
Published in
Clinical and experimental medicine
Chimeric antigen receptor (CAR) T cell therapy has come of age, offering a potentially curative option for patients who are refractory to standard anti-cancer treatments. The success of CAR T cell therapy in the setting of acute lymphoblastic leukemia and specific types of B cell lymphoma led to rapid regulatory approvals of CD19-directed CAR T cel...
Cao, Chunyu Wang, Changjiang
Published in
Clinical and experimental medicine
The purpose of this study was to reveal the clinical diagnostic and prognostic value of miR-768-3p in HBV-related HCC and to investigate its effect on the biological function of HCC. Quantitative real-time polymerase chain reaction was used to detect the expression level of miR-768-3p in subjects' serum. The receiver operating characteristics curve...
Wu, Biyu Chen, Shurong Zhuang, Lihong Zeng, Jingyang
Published in
Clinical and experimental medicine
Venous thromboembolism (VTE) is a common complication of colon cancer. In the present study, we aimed to explore the association of the oncogene COX7C to VTE in colon cancer patients. Samples from 580 patients were examined histologically for VTE and pathological characteristic of cancer. Gene mutation and expression analysis were performed using p...
El-Ashmawy, Nahla E Khedr, Naglaa F Mansour, Mohamed G Al-Ashmawy, Ghada M
Published in
Clinical and experimental medicine
Gastrointestinal (GIT) cancers represent the third common cancers worldwide, characterized by rapid progression and higher mortality rate. Matrix metalloproteinases (MMPs) play an important role in cancer metastases. The present study was conducted to estimate and evaluate the role of MMP-7, -9, -10 and -12 and TGF β1 along with conventional biomar...
