Mu, Huiwen Zhang, Sujie Yao, Zhaoying Liu, Yunxin Lin, Kang Zhao, Zheng Zhu, Yubing
Published in
Clinical and experimental medicine
Exosome-derived long non-coding RNAs (lncRNAs) as novel biomarkers are widely investigated in various cancers, yet results remain controversial. The aim of this meta-analysis was to clarify the diagnostic and prognostic value of exosome-derived lncRNAs in cancer. PubMed, Web of Science, EMBASE, CNKI, and WanFang online databases were comprehensivel...
Qu, Lili Cai, Xiaoxiao Xu, Junwen Wei, Xiaowei Qu, Xiaojun Sun, Li Gong, Lailing Su, Chuan Zhu, Yefei
Published in
Clinical and experimental medicine
To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded from The Cancer Genome Atlas (TCGA) database, were identified by edgeR package. CeRNA network was constructed based on miRcode, TargetScan, a...
Wang, Xiaoyue Xu, Yan Gui, Weiwei Hui, Feng Liao, Hui
Published in
Clinical and experimental medicine
To review the efficacy and safety of glucocorticoids combined with different regimens for treating severe immune thrombocytopenia (ITP). Eighty-five severe ITP patients from 2 tertiary hospitals treated with glucocorticoids were enrolled from January 2018 to May 2019 and divided into 4 treatment groups: group A (treated with glucocorticoids), group...
Blum, Arnon Meerson, Ari Rohana, Hanan Jabaly, Hanin Nahul, Nahul Celesh, Dorina Romanenko, Olga Tamir, Snait
Published in
Clinical and experimental medicine
To test the hypothesis that microRNAs may play a role in diabetic retinopathy, we measured the levels of different markers [microRNAs, vascular endothelial growth factor (VEGF), nitric oxide (NO), and total antioxidant capacity (TAO)] in patients with type 2 diabetes mellitus (T2DM) and microvascular complications. Sixty-nine patients were recruite...
Peng, Yue Pei, Qiongfei Feng, Siqi Su, Ya Liu, Ruixi Yi, Qijian Guo, Pengfei
Published in
Clinical and experimental medicine
The purpose of this study was to examine the serum levels of fibroblast growth factor 21 (FGF21) in children with acute Kawasaki disease (KD) and to investigate its relationship with coronary artery lesions (CALs). Blood samples from 58 children with KD before intravenous immunoglobulin treatment and from 28 healthy children as control group were c...
Mytsyk, Yulian Borys, Yuriy Tumanovska, Lesia Stroy, Dmytro Kucher, Askold Gazdikova, Katarina Rodrigo, Luis Kruzliak, Peter Prosecky, Robert Urdzik, Peter
...
Published in
Clinical and experimental medicine
None of the currently investigated molecular markers demonstrated sufficient accuracy in prognostication of the renal cell carcinoma (RCC) oncologic outcomes; thus, none of them has been recommended for the application in the routine clinical practice. The role of miR-15a as a potential prognostic marker for RCC is still not unveiled. The aim of ou...
Xin, Feng Yao, Dong-Wei Fan, Li Liu, Jiu-Hua Liu, Xiao-Dong
Published in
Clinical and experimental medicine
Bladder cancer is the second most common urological cancer worldwide with low early diagnosis and high mortality. Since the time of diagnosis directly affects survival rate, early detection and precise biomarkers of bladder cancer are very important. Adenylate kinase 4 (AK4) is a key enzyme involved in cellular metabolism and multiple cancer develo...
Zhong, Zheng-Xia Tan, Jia-Xing Tang, Yi Tan, Li Pei, Gai-Qin Qin, Wei
Published in
Clinical and experimental medicine
Henoch-Schönlein purpura nephritis (HSPN) is a common secondary glomerulonephritis, and its prognosis mainly depends on the severity of renal impairment. To date, the significance of crescent lesions in adult-onset HSPN is still unclear. Therefore, the purpose of this research was to assess whether crescents could predict the renal outcomes in adul...
Fu, Peng Xie, Shouxiang Zhang, Xiangcheng
Published in
Clinical and experimental medicine
Interleukin (IL)-8 has been reported to be associated with the progression of sepsis. Recent studies have explored the relationship between the IL-8 - 251 A/T polymorphism and sepsis risk. This study evaluated the association between the IL-8 - 251 A/T polymorphism and sepsis susceptibility in a Chinese Han population. We designed a case-control st...
Zhou, Fan Xu, Tingting Deng, Chunyan Yu, Haiyan Wang, Xiaodong
Published in
Clinical and experimental medicine
Thrombocytopenia is the second most common hematological disease during pregnancy and is mainly caused by gestational thrombocytopenia, immune thrombocytopenia, or preeclampsia/HELLP syndrome. This study aims to investigate the causes and pregnancy outcomes of thrombocytopenia in pregnancies with platelet counts below 50 × 109/L. We retrospectively...
