El Sagheer, Ghada M Ahmad, Asmaa K Abd-ElFattah, Aliaa S Saad, Zienab M Hamdi, Lamia
Published in
Clinical and experimental gastroenterology
Fibroblast growth factor (FGF) 21 was reported to be induced by different injurious agents, including chronic hepatitis C (CHC) virus, affecting the liver. The aims of this study were to evaluate the FGF21 levels in CHC patients before and after the treatment with direct-acting antiviral agents (DAAs) in comparison to that in control subjects and t...
Watanabe, Norikazu Suzuki, Masataka Yamaguchi, Yoshitake Egashira, Yukari
Published in
Clinical and experimental gastroenterology
It is well known that dietary fiber helps to relieve and prevent constipation, and there are a number of scientific papers, including systematic reviews and meta-analyses on the effects of naturally derived dietary fiber on bowel movements. In recent years, there has been an increase in the manufacture of dietary fiber ingredients obtained from foo...
Harki, Jihan Suker, Mustafa Tovar-Doncel, M Sherezade van Dijk, Louisa Jd van Noord, Désirée van Eijck, Casper Hj Bruno, Marco J Kuipers, Ernst J Ince, Can
Published in
Clinical and experimental gastroenterology
Little is known about the microcirculatory alterations in patients with chronic mesenteric ischemia (CMI). We hypothesized that patients with CMI have an impaired microcirculatory function and show an oral microcirculatory response after caloric challenge compared to healthy controls. All patients and controls received the standard workup for CMI. ...
Bantel, Carsten Tripathi, Shiva S Molony, David Heffernan, Tony Oomman, Susmita Mehta, Vivek Dickerson, Sara
Published in
Clinical and experimental gastroenterology
Opioids are an effective treatment for moderate-to-severe pain. However, they are associated with a number of gastrointestinal side effects, most commonly constipation. Laxatives do not target the underlying mechanism of opioid-induced constipation (OIC), so many patients do not have their symptoms resolved. Fixed-dose prolonged-release (PR) oxycod...
Uemura, Naomi Kinoshita, Yoshikazu Haruma, Ken Yao, Takashi Kushima, Ryoji Kanoo, Tatsuhiro
Published in
Clinical and experimental gastroenterology
Erosive esophagitis (EE) occurs when the epithelial mucosa is damaged due to gastric acid reflux, and the incidence of this disease is increasing in Japan due to changes in diet and lifestyle. The condition can be treated using proton pump inhibitors (PPIs) that act by irreversibly blocking the H+,K+-ATPase responsible for acid secretion. Vonopraza...
Malaty, Hoda M Lo, Grace Hsiao-Wei Hou, Jason K
Published in
Clinical and experimental gastroenterology
Spondyloarthritis among patients with IBD is usually diagnosed after the initial diagnosis of IBD. No difference in the prevalence of AS or peripheral arthritis was observed by IBD type, age, or race. Recognition and understanding of these results will have important implications for the management of IBD patients with spondyloarthritis.
Sioka, Eleni Tzovaras, George Tsiopoulos, Fotios Papamargaritis, Dimitris Potamianos, Spyros Chatzitheofilou, Constantine Zacharoulis, Dimitris
Published in
Clinical and experimental gastroenterology
Laparoscopic sleeve gastrectomy (LSG) modifies the upper gastrointestinal tract motility. Controversial data currently exist. The aim of the study was to evaluate esophageal motility before and after LSG. Morbid obese patients scheduled for LSG underwent reflux symptoms evaluation and manometry preoperatively and postoperatively. The preoperative a...
Matsumoto, Satohiro Kawamura, Haruna Nishikawa, Takeshi Sagihara, Noriyoshi Miyatani, Hiroyuki Mashima, Hirosato
Published in
Clinical and experimental gastroenterology
Rapid induction therapy with TAC tended to be selected for active UC patients with endoscopic evidence of severe disease, and the present study supported the validity of this therapeutic approach. However, transition to the remission-maintenance phase was more favorable in the anti-TNF group.
Aizawa, Yoshio Hokari, Atsushi
Published in
Clinical and experimental gastroenterology
Autoimmune hepatitis (AIH) is a chronic progressive liver disease characterized by high levels of aminotransferases and autoantibodies, hypergammaglobulinemia, and interface hepatitis. AIH affects all races and all ages worldwide, regardless of sex, although a preponderance of females is a constant finding. The etiology of AIH has not been complete...
Haque, Seraj Zohurul Haque, Mainul
Published in
Clinical and experimental gastroenterology
The human gastrointestinal tract is inhabited by a vast population of bacteria, numbering ~100 trillion. These microorganisms have been shown to play a significant role in digestion, metabolism, and the immune system. The aim of this study was to review and discuss how the human body interacts with its gut microbiome and in turn the effects that th...
