Buti, Sebastiano Petrelli, Fausto Ghidini, Antonio Vavassori, Ivano Maestroni, Umberto Bersanelli, Melissa
Published in
Clinical and Translational Oncology
PurposeConsidering the recent publication of the results of several clinical trials for metastatic clear cell renal cell carcinoma (mRCC), we performed a systematic review and meta-analysis of randomized studies comparing standard first-line VEGFR-targeted therapy to immune checkpoint inhibitors-based combinations for mRCC patients.Methods3960 pati...
Remon, J. García-Campelo, R. de Álava, E. Vera, R. Rodríguez-Peralto, J. L. Rodríguez-Lescure, Á. Bellosillo, B. Garrido, P. Rojo, F. Álvarez-Alegret, R.
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Published in
Clinical and Translational Oncology
The proportion of cancer patients with tumours that harbour a potentially targetable genomic alteration is growing considerably. The diagnosis of these genomic alterations can lead to tailored treatment at the onset of disease or on progression and to obtaining additional predictive information on immunotherapy efficacy. However, in up to 25% of ca...
Baldelli, G. De Santi, M. Gervasi, M. Annibalini, G. Sisti, D. Højman, P. Sestili, P. Stocchi, V. Barbieri, E. Brandi, G.
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Published in
Clinical and Translational Oncology
PurposeThere is growing evidence of an association between physical activity and a reduced risk of cancer and cancer recurrence. The aim of this study was to assess the effects of exercise-conditioned human serum (HS) effects on the proliferative and tumorigenic potential of triple-negative breast cancer (TNBC) and prostate cancer (PC) cells. Moreo...
Magallón-Pedrera, I. Pérez-Altozano, J. Virizuela Echaburu, J. A. Beato-Zambrano, C. Borrega-García, P. de la Torre-Montero, J. C.
Published in
Clinical and Translational Oncology
PurposeCancer patients require implantation of venous access devices to meet their personalized therapeutic needs, which are often complex due to the nature of the medication and the disease status. Therefore, it is essential to have standardized protocols that guarantee the best results in health and patient safety.MethodsTo learn about the availa...
Rezaeeniya, F.
Published in
Clinical and Translational Oncology
Passaro, A. Mancuso, P. Gandini, S. Spitaleri, G. Labanca, V. Guerini-Rocco, E. Barberis, M. Catania, C. Del Signore, E. de Marinis, F.
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Published in
Clinical and Translational Oncology
PurposeImmunotherapy is a new standard first-line treatment for non-small cell lung cancers (NSCLC) with high programmed cell death-ligand 1 (PD-L1) expression (≥ 50%) and second-line treatment regardless of PD-L1 status, though not all patients benefit from this approach. Much effort is ongoing to identify robust prognostic and predictive biomarke...
Alvarez-SanNicolas, J. Gracia-Alegria, I. Trullols-Tarrago, L. Peiro-Ibañez, A. Lamas-Gomez, C.
Published in
Clinical and Translational Oncology
PurposeSurvival in Ewing’s sarcoma (ES) has increased with the use of chemotherapy. Surgical techniques such as limb salvage (LS) have been developed. Survival and adverse events have been widely studied in general series of ES, but there are few specific series of ES cases treated by LS, despite this being the most commonly used (surgical) approac...
Lázaro, M. Gallardo, E. Doménech, M. Pinto, Á. González-del-Alba, A. Puente, J. Fernández, O. Font, A. Lainez, N. Vázquez, S.
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Published in
Clinical and Translational Oncology
Due to a technical issue, the family name of the author
Zhao, Y. Qiao, G. Wang, X. Song, Y. Zhou, X. Jiang, N. Zhou, L. Huang, H. Zhao, J. Morse, M. A.
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Published in
Clinical and Translational Oncology
BackgroundAdvanced non-small cell lung cancer (NSCLC) has remained challenging to treat effectively. This study aimed to investigate the clinical effects and safety of immunotherapy with dendritic cells and cytokine-induced killer cells (DC-CIK) administered with chemotherapy (CT) in this malignancy.MethodsWe have developed a new clinical trial des...
Tuerxun, H. Cui, J.
Published in
Clinical and Translational Oncology
Morphine is a classic opioid drug used for reducing pain and is commonly prescribed as an effective drug to control cancer pain. Morphine has a direct role in the central nervous system to relieve pain, but because of its peripheral functions, morphine also has some side effects, such as nausea, constipation, and addiction (Gupta et al. in Sci Worl...
