Vantur, Romana Rihar, Marusa Koren, Ana Rijavec, Matija Kopac, Peter Bidovec-Stojkovic, Urska Erzen, Renato Korosec, Peter
Published in
Clinical and Translational Allergy
BackgroundThe role of chemokines in anaphylaxis is unclear.MethodsWe prospectively recruited 49 patients presenting to the emergency department with an acute episode of anaphylaxis and 28 healthy subjects. We measured serum levels of the chemokines CCL2, CCL5, CCL7, CCL8, CCL11, CCL13, CCL17, CCL21, CCL22, CCL24, and CCL26, tryptase, the absolute n...
Qi, Cancan Vonk, Judith M. van der Plaat, Diana A. Nieuwenhuis, Maartje A. E. Dijk, F. Nicole Aïssi, Dylan Siroux, Valérie Boezen, H. Marike Xu, Cheng-jian Koppelman, Gerard H.
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Published in
Clinical and Translational Allergy
BackgroundAsthma is a chronic respiratory disease which is not curable, yet some patients experience spontaneous remission. We hypothesized that epigenetic mechanisms may be involved in asthma remission.MethodsClinical remission (ClinR) was defined as the absence of asthma symptoms and medication for at least 12 months, and complete remission (ComR...
Bédard, A. Basagaña, X. Anto, J. M. Garcia-Aymerich, J. Devillier, P. Arnavielhe, S. Bedbrook, A. Onorato, G. L. Czarlewski, W. Murray, R.
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Published in
Clinical and Translational Allergy
BackgroundThe analysis of mobile health (mHealth) data has generated innovative insights into improving allergic rhinitis control, but additive information is needed. A cross-sectional real-world observational study was undertaken in 17 European countries during and outside the estimated pollen season. The aim was to collect novel information inclu...
Ding, Yuanyuan Zhang, Tao Liu, Rui Che, Delu Wang, Nan He, Langchong
Published in
Clinical and Translational Allergy
BackgroundMas-related G-protein coupled receptor member X2 (MrgX2) directly mediates drug-induced pseudo allergic reactions. Skin mast cell MrgX2 is upregulated in severe chronic urticaria (CU). Mast cells and leukocytes are key effector cells in allergic reactions and undergo degranulation upon stimulation. It is unknown whether circulating MrgX2 ...
Vanoverschelde, Anna van der Wel, Paulien Putman, Barbara Lahousse, Lies
Published in
Clinical and Translational Allergy
Bogas, Gador Mayorga, Cristobalina Martín-Serrano, Ángela Fernández-Santamaría, Rubén Jiménez-Sánchez, Isabel M. Ariza, Adriana Barrionuevo, Esther Posadas, Teresa Salas, María Fernández, Tahía Diana
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Published in
Clinical and Translational Allergy
BackgroundAnalysis of cross-reactivity is necessary for prescribing safe cephalosporins for penicillin allergic patients. Amoxicillin (AX) is the betalactam most often involved in immediate hypersensitivity reactions (IHRs), and cefadroxil (CX) the most likely cephalosporin to cross-react with AX, since they share the same R1 side chain, unlike cef...
Bousquet, J. Grattan, C. E. Akdis, C. A. Eigenmann, P. A. Hoffmann-Sommergruber, K. Agache, I. Jutel, M.
Published in
Clinical and Translational Allergy
The European Academy of Allergy and Clinical Immunology (EAACI) owns three journals: Allergy, Pediatric Allergy and Immunology and Clinical and Translational Allergy. One of the major goals of EAACI is to support health promotion in which prevention of allergy and asthma plays a critical role and to disseminate the knowledge of allergy to all stake...
Bousquet, Jean Cristol, Jean-Paul Czarlewski, Wienczyslawa Anto, Josep M. Martineau, Adrian Haahtela, Tari Fonseca, Susana C. Iaccarino, Guido Blain, Hubert Fiocchi, Alessandro
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Published in
Clinical and Translational Allergy
There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) an...
Ehlers, Anna M. Rohwer, Stefanie Otten, Henny G. Brix, Bettina Le, Thuy-My Suer, Waltraud Knulst, André C.
Published in
Clinical and Translational Allergy
BackgroundMacadamia nut can induce fatal allergic reactions and changes in dietary habits will raise their consumption in industrialised countries. Until now diagnosis of macadamia nut allergy by sIgE solely relies on the macadamia nut extract, but single components are lacking.MethodsMacadamia nut proteins recognised by IgE from 2 macadamia nut ex...
Xu, Ying-Yang Gu, Jian-Qing Zhi, Yu-Xiang
Published in
Clinical and Translational Allergy
BackgroundHereditary angioedema with deficient and dysfunctional C1 inhibitor (C1-INH-HAE) is a rare genetic disorder. The majority of the cases with this disease are caused by mutations in the C1-inbitor gene SERPING1 and are classified as type 1 and type 2. We aimed to detect mutations in the SERPING1 gene and evaluate its expression in nine prob...
