Systemic therapy in advanced hepatocellular carcinoma.
Published in Clinical and molecular hepatology
Systemic therapy in advanced hepatocellular carcinoma.
Neuropilins as potential biomarkers in hepatocellular carcinoma: a systematic review of basic and clinical implications....
Published in Clinical and molecular hepatology
Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers worldwide and is characterized by complex molecular carcinogenesis. Neuropilins (NRPs) NRP1 and NRP2 are the receptors of multiple proteins involved in key signaling pathways associated with tumor progression. We aimed to systematically review all the available findings on ...
Non-invasive imaging biomarkers for liver steatosis in non-alcoholic fatty liver disease: present and future
Published in Clinical and Molecular Hepatology
Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease.
Published in Clinical and molecular hepatology
Immune and inflammatory cells respond to multiple pathological hits in the development of nonalcoholic steatohepatitis (NASH) and fibrosis. Relatively little is known about how their type and function change through the non-alcoholic fatty liver disease (NAFLD) spectrum. Here we used multi-dimensional mass cytometry and a tailored bioinformatic app...
The role of different viral biomarkers on the management of chronic hepatitis B.
Published in Clinical and molecular hepatology
Chronic hepatitis B infection is a major public health challenge. With the advancement in technology, various components of the viral cycle can now be measured in the blood to assess viral activity. In this review article, we summarize the relevant data of how antiviral therapies impact viral biomarkers, and discuss their potential implications. Vi...
Global burden of primary liver cancer and its association with underlying aetiologies, sociodemographic status, and sex ...
...
Published in Clinical and molecular hepatology
Global distribution of dominant liver cancer aetiologies has significantly changed over the past decades. This study analyzed the updated temporal trends of liver cancer aetiologies and sociodemographic status in 204 countries and territories from 1990 to 2019. The Global Burden of Disease 2019 report was used for statistical analysis. In addition,...
Utility of combining PIVKA-II and AFP in the surveillance and monitoring of hepatocellular carcinoma in the Asia-Pacific...
...
Published in Clinical and molecular hepatology
Even though the combined use of ultrasound (US) and alpha-fetoprotein (AFP) is recommended for the surveillance of hepatocellular carcinoma (HCC), the utilization of AFP has its challenges, including accuracy dependent on its cut-off levels, degree of liver necroinflammation, and etiology of liver disease. Though various studies have demonstrated t...
Chronic hepatitis B with concurrent metabolic dysfunction-associated fatty liver disease: Challenges and perspectives.
Published in Clinical and molecular hepatology
The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) has increased among the general population and chronic hepatitis B (CHB) patients worldwide. Although fatty liver disease is a well-known risk factor for adverse liver outcomes like cirrhosis and hepatocellular carcinoma, its interactions with the hepatitis B virus (HBV)...
Letter regarding "Long-term prognosis and the need for histologic assessment of chronic hepatitis B in the serological i...
Published in Clinical and molecular hepatology
The independent effect of exercise on biopsy proven non-alcoholic fatty liver disease: A systematic review.
Published in Clinical and molecular hepatology
