Simoni, Y. Diana, J. Ghazarian, L. Beaudoin, L. Agnès Lehuen
Published in
Clinical & Experimental Immunology
T cells reactive to lipids and restricted by major histocompatibility complex (MHC) class I-like molecules represent more than 15% of all lymphocytes in human blood. This heterogeneous population of innate cells includes the invariant natural killer T cells (iNK T), type II NK T cells, CD1a,b,c-restricted T cells and mucosal-associated invariant T ...
Erik Ames Hallett, Wd William Murphy
Published in
Clinical & Experimental Immunology
Burton, C T Goodall, R L Samri, A Autran, B Kelleher, A D Poli, G Pantaleo, G Gotch, F M Imami, N
Published in
Clinical and experimental immunology
INITIO is an open-labelled randomized trial evaluating first-line therapeutic strategies for human immunodeficiency virus-1 (HIV-1) infection. In an immunology substudy a tetanus toxoid booster (TTB) immunization was planned for 24 weeks after initiation of highly active antiretroviral therapy (HAART). All patients had received tetanus toxoid immun...
Levy, R J Haidar, M Park, H Tar, L Levinson, A I
Published in
Clinical & Experimental Immunology
The present studies were carried out to further characterize the polyclonal B cell activating properties of bacterial peptidoglycan (PG) and to determine if this ubiquitous agent induces in vitro IgM rheumatoid factor (RF) production by lymphocytes from healthy volunteers. Peripheral blood mononuclear cells (PBMC) were cultured in the presence of p...
Gail Sckisel Tietze, Jk Zamora, Ae Hsiao, Hh Priest, So Wilkins, De Lanier, Ll Blazar, Br Baumgarth, N William Murphy
...
Published in
Clinical & Experimental Immunology
Primary viral infections induce activation of CD8(+) T cells responsible for effective resistance. We sought to characterize the nature of the CD8(+) T cell expansion observed after primary viral infection with influenza. Infection of naive mice with different strains of influenza resulted in the rapid expansion of memory CD8(+) T cells exhibiting ...