He, Lianhua Luan, Huijie He, Juan Zhang, Miaomiao Qin, Qingxia Hu, Yiping Cai, Yueming Sun, Desheng Shi, Yu Wang, Qingwen
...
Published in
Chinese Medicine
Background Rheumatoid arthritis is a progressive and systemic autoimmune disease seriously compromises human health. Fibroblast like synoviocytes are the major effectors of proliferation and inflammation in rheumatoid arthritis synovial tissue. Shikonin has anti-inflammatory and immunomodulatory activities. But, its role on synovitis of rheumatoid ...
Zhang, Xian You, Lifang Zhang, Xiaohui Wang, Fangfang Wang, Yi Zhou, Jue Liu, Chang Qu, Fan
Published in
Chinese Medicine
Background Chinese herbal medicine (CHM) has significant effects that improve the reproductive functions of patients with polycystic ovary syndrome (PCOS). However, the intergenerational effects of CHM on offspring and the underlying mechanism of CHM remain unclear. This study aimed to explore the effects and the underlying mechanism of CHM, specif...
Li, Zhe Ryenchindorj, Lkhaasuren Liu, Bonan Shi, Ji Zhang, Chao Hua, Yue Liu, Pengpeng Shan, Guoshun Jia, Tianzhu
Published in
Chinese Medicine
Background Chinese materia medica processing is a distinguished and unique pharmaceutical technique in Traditional Chinese Medicine (TCM) used for reducing side effects, and increasing or even changing therapeutic efficacy of the raw herbs.Changes in the essential components induced by an optimized processing procedure are primarily responsible for...
Zhou, Fangfang Aipire, Adila Xia, Lijie Halike, Xierenguli Yuan, Pengfei Sulayman, Mamtimin Wang, Weilan Li, Jinyao
Published in
Chinese Medicine
Background Marchantia polymorpha L. is a kind of Chinese herbal medicine and has various biological activities including antioxidant and antifungal. However, it is not clear about the antitumor effect and mechanism of M. polymorpha . We prepared M. polymorpha ethanol extract (MPEE) and investigated its antitumor effect on hepatocellular carcinoma c...
Han, Lin Yang, Hao-yu Zheng, Yu-jiao Wei, Xiu-xiu Dan, Wen-chao Zhang, Li-li Ding, Qi-you Ma, Xu Wang, Xin-miao Zhao, Lin-hua
...
Published in
Chinese Medicine
Background The Gouqi-wentang formula (GQWTF) is a herbal formula used by Academician Xiao-lin Tong for the clinical treatment of T2DM. GQWTF is beneficial to qi, nourishes Yin, clears heat, and promotes fluid production, but the effective components and their mechanism of action remain unclear. Methods The main components of GQWTF were detected by ...
Zhang, Chen Chen, Zhejie He, Yanan Xian, Jing Luo, Ruifeng Zheng, Chuan Zhang, Jinming
Published in
Chinese Medicine
Background The oral colon-targeting drug delivery vehicle is vital for the efficient application of curcumin (Cur) in ulcerative colitis (UC) treatment because of its lipophilicity and instability in the gastrointestinal tract. Methods The core–shell microparticle (MP) system composed of eco-friendly materials, zein and shellac, was fabricated usin...
Song, Zhizhen Li, Zeyun Wen, Xueqian Liu, Ruijuan Tian, Xin
Published in
Chinese Medicine
Background Epimedin C, one of the main active ingredients of Epimedium, has been reported to have potential hepatotoxicity. However, the mechanism of Epimedin C-induced liver injury has not been studied. mRNA methylation, mainly including N 6-methyladenosine and N 5-methylcytidine, is implicated in the regulation of many biological processes and di...
Liao, Xuejiao Guo, Shuai Yin, Xianmei Liao, Baosheng Li, Mingqian Su, He Li, Qiushi Pei, Jin Gao, Jihai Lei, Juan
...
Published in
Chinese Medicine
Background Bungarus multicinctus , from which a classical Chinese medicine is produced, is known as the most venomous land snake in the world, but the chromatin organization and transcription factor activity during venom replenishment progress have not been explored yet. This study aimed to determine the roles of chromatin structure in toxin activi...
Hu, Qi He, Yanan Wang, Fang Wu, Jing Ci, Zhimin Chen, Lumeng Xu, Runchun Yang, Ming Lin, Junzhi Han, Li
...
Published in
Chinese Medicine
Microwave technology is used throughout the world to generate heat using energy from the microwave range of the electromagnetic spectrum. It is characterized by uniform energy transfer, low energy consumption, and rapid heating which preserves much of the nutritional value in food products. Microwave technology is widely used to process food such a...
Chen, Rong-Bin Yang, Ying-Dong Sun, Kai Liu, Shan Guo, Wei Zhang, Jin-Xin Li, Yong
Published in
Chinese Medicine
Background Amending from ancient classic, Ziyin Tongluo Formula (ZYTLF) has been prescribed to treat postmenopausal osteoporosis (PMOP) for decades with good curative effect. However, the possible mechanisms of it are still unknown. Methods Ovariectomized rat model was established to validate the therapeutic effect of ZYTLF on PMOP by Micro-CT bone...
