A Place for Large Language Models in Scientific Publishing, Apart from Credited Authorship
Published in Cellular and Molecular Bioengineering
A Place for Large Language Models in Scientific Publishing, Apart from Credited Authorship
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells.
Published in Cellular and molecular bioengineering
Women are at elevated risk for certain cardiovascular diseases, including pulmonary arterial hypertension, Alzheimer's disease, and vascular complications of diabetes. Angiotensin II (AngII), a circulating stress hormone, is elevated in cardiovascular disease; however, our knowledge of sex differences in the vascular effects of AngII are limited. W...
Can Bard, Google’s Experimental Chatbot Based on the LaMDA Large Language Model, Help to Analyze the Gender and Racial D...
Published in Cellular and Molecular Bioengineering
There is a growing recognition that scientific articles featuring women and people of color as first and last (senior) author are undercited in the literature relative to male and non-minority race authors. Some limited tools now exist to analyze the diversity of manuscript bibliographies, with acknowledged limitations. Recently the journal editors...
Artificial Intelligence, Chatbots, Plagiarism and Basic Honesty: Comment.
Published in Cellular and molecular bioengineering
Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the miR-338-3p/ZFX Axis and Activating the ME...
Published in Cellular and molecular bioengineering
Colorectal cancer (CRC) is a common malignant tumor in the digestive tract. Circular RNAs (circRNAs) have been identified as crucial regulators of tumorigenesis. However, the role and potential mechanism of circ_0004585 in CRC are poorly understood. The expression of circ_0004585, microRNA-338-3p (miR-338-3p), and zinc finger protein X-linked (ZFX)...
Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast C...
Published in Cellular and molecular bioengineering
Drug targeting and controlled drug release systems in cancer treatment have many advantages over conventional chemotherapy in terms of limiting systemic toxicity, side effects, and overcoming drug resistance. In this paper, fabricating nanoscale delivery system composed of magnetic nanoparticles (MNPs) covered with poly-amidoamine (PAMAM) dendrimer...
Tumor-Targeting Extracellular Vesicles Loaded with siS100A4 for Suppressing Postoperative Breast Cancer Metastasis.
...Published in Cellular and molecular bioengineering
S100A4 promotes the establishment of tumor microenvironment for malignant cancer cells, and knockdown of S100A4 can inhibit tumorigenesis. However, there is no efficient way to target S100A4 in metastatic tumor tissues. Here, we investigated the role of siS100A4-loaded iRGD-modified extracellular vesicles (siS100A4-iRGD-EVs) in postoperative breast...
An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo
Published in Cellular and Molecular Bioengineering
Background Identification and quantitation of newly synthesized proteins (NSPs) are critical to understanding protein dynamics in development and disease. Probing the nascent proteome can be achieved using non-canonical amino acids (ncAAs) to selectively label the NSPs utilizing endogenous translation machinery, which can then be quantitated with m...
Osmotic Contribution of Synthesized Betaine by Choline Dehydrogenase Using In Vivo and In Vitro Models of Post-traumatic...
Published in Cellular and molecular bioengineering
Syringomyelia (SM) is a debilitating spinal cord disorder in which a cyst, or syrinx, forms in the spinal cord parenchyma due to congenital and acquired causes. Over time syrinxes expand and elongate, which leads to compressing the neural tissues and a mild to severe range of symptoms. In prior omics studies, significant upregulation of betaine and...
Stiffer-Matrix-Induced PGC-1α Upregulation Enhanced Mitochondrial Biogenesis and Oxidative Stress Resistance in Non-smal...
Published in Cellular and molecular bioengineering
Metabolic strategies in different microenvironments can affect cancer metabolic adaptation, ultimately influencing the therapeutic response. Understanding the metabolic alterations of cancer cells in different microenvironments is critical for therapeutic success. In this study, we cultured non-small cell lung cancer cells in three different microe...
