Bourron, Olivier Phan, Franck Diallo, Mamadou Hassimiou Hajage, David Aubert, Carole-Elodie Carlier, Aurélie Salem, Joe-Elie Funck-Brentano, Christian Kemel, Salim Cluzel, Philippe
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Published in
Cardiovascular Diabetology
BackgroundLower limb arterial calcification is a frequent, underestimated but serious complication of diabetes. The DIACART study is a prospective cohort study designed to evaluate the determinants of the progression of lower limb arterial calcification in 198 patients with type 2 diabetes.MethodsLower limb arterial calcification scores were determ...
Dettori, Rosalia Milzi, Andrea Burgmaier, Kathrin Almalla, Mohammad Hellmich, Martin Marx, Nikolaus Reith, Sebastian Burgmaier, Mathias
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Cardiovascular Diabetology
BackgroundType 2 diabetes mellitus (T2DM) is associated with an increased cardiovascular risk related at least in part to a more vulnerable plaque phenotype. However, patients with T2DM exhibit also an increased risk following percutaneous coronary intervention (PCI). It is unknown if plaque vulnerability of a treated lesion influences cardiovascul...
Park, Se-Jun Ha, Kyoung Hwa Kim, Dae Jung
Published in
Cardiovascular Diabetology
BackgroundThe “obesity paradox” has not been elucidated in the long-term outcomes of acute coronary syndrome (ACS). We investigated the association between obesity and cardiovascular (CV) outcomes in ACS patients with and without diabetes.MethodsWe identified 6978 patients with ACS aged 40–79 years from the Korean National Health Insurance Service-...
Morieri, Mario Luca Avogaro, Angelo Fadini, Gian Paolo
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Cardiovascular Diabetology
BackgroundThe well-established benefit of Low-Dense-Lipoprotein-cholesterol (LDL-c) lowering treatments (LLTs) has led clinical guidelines to lower the cardiovascular prevention targets. Despite this, there is a surprising scarcity of real-world studies (RWS) evaluating whether recommendations are applied in the routine clinical management of patie...
Chen, Tien-Hsing Li, Yan-Rong Chen, Shao-Wei Lin, Yu-Sheng Sun, Chi-Chin Chen, Dong-Yi Mao, Chun-Tai Wu, Michael Chang, Chih-Hsiang Chu, Pao-Hsien
...
Published in
Cardiovascular Diabetology
BackgroundSodium-glucose co-transporter 2 inhibitors (SGLT2i) has shown evidence of cardiovascular benefit in patients with type 2 diabetes mellitus (T2DM). Currently metformin is the guideline-recommended first-line treatment. We aimed to investigate the benefit of SGLT2i vs metformin as first-line therapy.MethodsElectronic medical records from Ch...
Ling, Ann Wan-Chin Chan, Cze-Ci Chen, Shao-Wei Kao, Yi-Wei Huang, Chien-Ying Chan, Yi-Hsin Chu, Pao-Hsien
Published in
Cardiovascular Diabetology
BackgroundSodium glucose cotransporter 2 inhibitor (SGLT2i) reduces the risk of hard cardiovascular endpoints in type 2 diabetes mellitus (T2DM) patients with/without established cardiovascular diseases. Whether SGLT2i is associated with a lower risk of new-onset atrial fibrillation (AF) in T2DM patients is unclear. We aimed to evaluate the risk of...
Macchi, C. Favero, C. Ceresa, A. Vigna, L. Conti, D. M. Pesatori, A. C. Racagni, G. Corsini, A. Ferri, N. Sirtori, C. R.
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Published in
Cardiovascular Diabetology
BackgroundDepression and cardiovascular disease (CVD) are among the most common causes of disability in high-income countries, depression being associated with a 30% increased risk of future CV events. Depression is twice as common in people with diabetes and is associated with a 60% rise in the incidence of type 2 diabetes, an independent CVD risk...
Zhang, Yuanyuan Zhou, Chun Li, Jianping Zhang, Yan Xie, Di Liang, Min Wang, Binyan Song, Yun Wang, Xiaobin Huo, Yong
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Cardiovascular Diabetology
BackgroundThe association between alkaline phosphatase (ALP) and incident diabetes remains uncertain. Our study aimed to investigate the prospective relation of serum ALP with the risk of new-onset diabetes, and explore possible effect modifiers, in hypertensive adults.MethodsA total 14,393 hypertensive patients with available ALP measurements and ...
Schernthaner, Guntram Shehadeh, Naim Ametov, Alexander S. Bazarova, Anna V. Ebrahimi, Fahim Fasching, Peter Janež, Andrej Kempler, Péter Konrāde, Ilze Lalić, Nebojša M.
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Published in
Cardiovascular Diabetology
The disclosure of proven cardiorenal benefits with certain antidiabetic agents was supposed to herald a new era in the management of type 2 diabetes (T2D), especially for the many patients with T2D who are at high risk for cardiovascular and renal events. However, as the evidence in favour of various sodium–glucose transporter-2 inhibitor (SGLT2i) ...
Bojer, Annemie Stege Sørensen, Martin Heyn Vejlstrup, Niels Goetze, Jens P. Gæde, Peter Madsen, Per Lav
Published in
Cardiovascular Diabetology
BackgroundCardiovascular magnetic resonance imaging (CMR) have described localised non-ischemic late gadolinium enhancement (LGE) lesions of prognostic importance in various non-ischemic cardiomyopathies. Ischemic LGE lesions are prevalent in diabetes (DM), but non-ischemic LGE lesions have not previously been described or systematically studied in...
