Claude, L Bouter, J Le Quellenec, G Padovani, L Laprie, A
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Cancer in childhood represent 1% of all the new diagnosed cancers. About 30% of children with cancer receive radiation therapy, representing about 600 to 700 patients per year in France. As a consequence, paediatric cancers with synchronous metastasis is a very rare situation in oncology, with usually poor standard of care. However, considerable ef...
Sargos, P Le Guevelou, J Khalifa, J Albiges, L Azria, D de Crevoisier, R Supiot, S Créhange, G Roubaud, G Chapet, O
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Metastatic bladder and renal cancers account respectively for 2.1% and 1.8% of cancer deaths worldwide. The advent of immune checkpoint inhibitors has revolutionized the management of metastatic disease, by demonstrating considerable improvements in overall survival. However, despite initial sensitivity to immune checkpoint inhibitors for most pati...
Tonneau, M Nebbache, R Larnaudie, A Thureau, S Pointreau, Y Blanchard, P Thariat, J
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Head and neck carcinomas are initially metastatic in about 15% of cases. Radiotherapy is a cornerstone in the multimodal strategy at the locoregional phase. In patients with head and neck cancer, often heavily pretreated and with comorbidities, who relapse locoregionally or at distant sites, radiotherapy has also become increasingly important at th...
Khalifa, J Lévy, A Sauvage, L-M Thureau, S Darréon, J Le Péchoux, C Lerouge, D Pourel, N Antoni, D Blais, E
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Metastatic lung cancer classically portends a poor prognosis. The management of metastatic lung cancer has dramatically changed with the emergence of immune checkpoint inhibitors, targeted therapy and due to a better understanding of the oligometastatic process. In metastatic lung cancers, radiation therapy which was only used with palliative inten...
Escande, A Leblanc, J Hannoun-Levi, J-M Renard, S Ducassou, A Hennequin, C Chargari, C
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Beyond classical palliative-intent irradiation schemes, there are increasing data suggesting a benefit for intensive locoregional treatments in metastatic gynecological cancers. Such approach aims at avoiding local symptoms related to tumor progression, but may also improve survival outcome by shrinking tumor burden to a microscopic state. This str...
Le Scodan, R Ghannam, Y Kirova, Y Bourgier, C Richard Tallet, A
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
De novo metastatic breast cancer represents 5 to 8% of all breast cancers (2500 new cases per year in France). Systemic treatment is the cornerstone of treatment, whereas radiation therapy usually has a palliative intent. Advances in systemic and local treatments (surgery and radiation therapy) have substantially improved overall survival. In the r...
Giraud, P Fleury, B Le Prince, C Falk, A T Rousse, C Hance, H Santini, J-J Bicheron, D Palisson, J Hannoun-Lévi, J-M
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Cybersecurity is currently a major issue. Large hospitals are no longer the only main targets of attacks, but all healthcare organizations and establishments, without distinction of size or activities. The information system is defined as all the resources needed to collect images, store and process them with general distribution of multiple inform...
Ma, Y Li, Q
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
The purpose of this study was to develop a model for predicting chemoradiation response in non-small cell lung cancer (NSCLC) patients by integrating radiomics and deep-learning features and combined intra- and peritumoral regions with pre-treated CT images. This study enrolled 462 patients with NSCLC who received chemoradiation. On the basis of pr...
Lapadula, L Piombino, M Bianculli, A Caivano, R Capobianco, A Cacciatore, A Cozzolino, M Oliviero, C D'andrea, B Mileo, A
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Whole brain reirradiation for the treatment of multiple brain metastases has shown promising results. However, concerns remain over the possible neurotoxic effects of the cumulative dose as well as the questionable radiosensitivity of recurrent metastases. A second reirradiation of the whole brain is ordinarily performed in our department for palli...
Hanslik, N Bourgier, C Thezenas, S Carrère, S Firmin, N Riou, O Azria, D Llacer-Moscardo, C
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Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Conserving surgery combined with radiotherapy in presence of local recurrence risk factors is standard treatment of soft tissue sarcomas, a group of rare and heterogeneous tumours. Radiotherapy is performed before or after surgery. In neoadjuvant setting, late radiation-induced toxicity is reduced and pathological response to radiotherapy could be ...