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Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses.

Published in Cancer cell

How immune dysregulation affects recovery from COVID-19 infection in patients with cancer remains unclear. We analyzed cellular and humoral immune responses in 103 patients with prior COVID-19 infection, more than 20% of whom had delayed viral clearance. Delayed clearance was associated with loss of antibodies to nucleocapsid and spike proteins wit...

Enhanced but variant-dependent serological and cellular immune responses to third-dose BNT162b2 vaccination in patients ...

Published in Cancer cell

Cancer vaccines

Published in Cancer Cell

Given the renewed interest in vaccine development sparked by the COVID-19 pandemic, we are revisiting the current state of vaccine development for cancer prevention and treatment. Experts discuss different vaccine types, their antigens and modes of action, and where we stand on their clinical development, plus the challenges we need to overcome for...

COVID-19 vaccines elicit robust cellular immunity and clinical protection in chronic lymphocytic leukemia.

Published in Cancer cell

Longitudinal COVID-19-vaccination-induced antibody responses and Omicron neutralization in patients with lung cancer.

Published in Cancer cell

Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies

Published in Cancer Cell

Augmentation of humoral and cellular immune responses after third-dose SARS-CoV-2 vaccination and viral neutralization i...

Published in Cancer cell

Enhanced SARS-CoV-2 breakthrough infections in patients with hematologic and solid cancers due to Omicron.

Published in Cancer cell

Risk factors for poor humoral response to primary and booster SARS-CoV-2 vaccination in hematologic and oncological outp...

Published in Cancer Cell

COVID-19 in patients with lymphoproliferative diseases during the Omicron variant surge

Published in Cancer Cell