Small cell glioblastoma multiforme: a case series and clinicopathological update
Published in CNS Oncology
Endocrine therapy for the treatment of leptomeningeal carcinomatosis in luminal breast cancer: a comprehensive review.
Published in CNS oncology
Leptomeningeal disease (LMD) represents a devastating complication of advanced breast cancer (ABC), with survival of
Intermixed arteriovenous malformation and hemangioblastoma: case report and literature review
Published in CNS Oncology
We report the third presentation of an intermixed arteriovenous malformation and hemangioblastoma. The rare occurrence of the diagnostic histologic features of both a neoplasm and vascular malformation in a single lesion is more common in gliomas, as angioglioma, and is termed an ‘intermixed’ lesion. We review the literature concerning the developm...
Time to treatment initiation and outcomes in high-grade glioma patients in rehabilitation: a retrospective cohort study
Published in CNS Oncology
Aims: To investigate wait time (WT) for chemoradiation and survival in post-op high-grade glioma (HGG) patients admitted to inpatient rehabilitation compared with those discharged home. Materials & methods: A total of 291 HGG patients (14.4% grade III and 84.9% grade IV) were included in this retrospective cohort study. Patients were grouped by dis...
Primary intradural Hodgkin lymphoma of the conus medullaris and cauda equina: case report
Published in CNS Oncology
Primary Hodgkin lymphoma of the central nervous system is an exceedingly rare condition with very few cases reported in the literature. Isolated intradural involvement of the spine is rarer still, with only two prior cases located in the extramedullary cervical and lumbosacral spine. We present a 48-year-old female who was presented with back pain,...
A view on the landscape of breast cancer brain metastases
Published in CNS Oncology
Development of CNS metastases in breast cancer patients treated with curative intent: a case–control study
Published in CNS Oncology
Background: The aim of this study was to identify risk factors that may predispose breast cancer patients to the development of CNS metastases. Materials & methods: We conducted a matched case–control study of breast cancer patients treated with surgery with curative intent. A total of 71 cases and 71 controls were analyzed, matched by year of surg...
Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience
Published in CNS Oncology
Aim: The purpose of the study is to perform a dosimetric analysis of the doses received by planning target volume and organ at risks in the postoperative glioblastoma by using 3D-conformal radiotherapy to a total dose of 60 Gy in 30 fractions. Materials & Methods: All patients received concurrent temozolomide every day, and this was followed by adj...
Ivosidenib, an IDH1 inhibitor, in a patient with recurrent, IDH1 -mutant glioblastoma: a case report from a Phase I stud...
Published in CNS Oncology
Glioblastoma is the most common and aggressive primary brain tumor. Despite standard multimodality therapy, median overall survival remains poor with a 5-year survival rate of approximately 5% in most studies (range 4.7–13.0%). Strong interest in targeting IDH mutations has led to a variety of studies in both hematologic malignancies and solid tumo...
Retention rates of antiepileptic drugs in glioma patients: the most appropriate outcome
Published in CNS Oncology
