Abdel Baky, Ashraf Omar, Tarek E. I. Amer, Yasser Sami
Published in
Bulletin of the National Research Centre
Background In Egypt, academic organizations, professional societies, and research groups develop clinical practice guidelines (CPGs) in order to improve patient quality care and safety. Although important improvements have been made over the past years, many of these consensus-based guideline documents still lack the transparency and methodological...
Adesola, Ridwan Olamilekan Miranda, Adriana Viola Tran, Yeuk Shun Joshua Idris, Ibrahim Lin, Xu Kouwenhoven, M. B. N. Lucero-Prisno, Don Eliseo III
Published in
Bulletin of the National Research Centre
Background and aims A new novel virus, Langya virus (LayV), was detected in China in August 2022, 3 years after the COVID-19 pandemic. LayV is similar to the previously discovered Mojiang henipavirus. Other zoonotic henipaviruses include the Hendra and Nipah viruses. The emergence of the zoonotic Langya virus is attributed to climate change and wil...
Aldossari, Hamad Mansur
Published in
Bulletin of the National Research Centre
Background COVID-19 affected the world threatening medical, social, economic and community dimensions. Along with the other countries of the world, Saudi Arabia also witnessed critical emergencies leading to serious disaster due mainly to the overcrowding at certain urban residential localities. Nevertheless, the situation handled meticulously not ...
Singh, Jitendra Arora, Rubeena Rawat, Vijay Singh, Vikas Goyal, Snigdha Joshi, Liza
Published in
Bulletin of the National Research Centre
COVID causes immunosuppression. COVID and diabetes mellitus together cause synergistic immune dysregulation. Such patients are very vulnerable to develop opportunistic infections like Mucormycosis. Our proposed screening protocol is easy-to-use even by minimally-trained healthcare workers. Asymptomatic patients diagnosed with mucormycosis are relat...
Kerama, Cheryl Horne, David Ong'ang'o, Jane Anzala, Omu
Published in
Bulletin of the National Research Centre
The END TB 2035 goal has a long way to go in low-income and low/middle-income countries (LICs and LMICs) from the perspective of a non-communicable disease (NCD) control interaction with tuberculosis (TB). The World Health Organization has identified diabetes as a determinant for, and an important yet neglected risk factor for tuberculosis. Nationa...
Madanagopal, Premnath Muthusamy, Sathya Pradhan, Satya Narayan Prince, Prabhu Rajaiah
Published in
Bulletin of the National Research Centre
Lymphatic filariasis (LF), often referred to as elephantiasis, has been identified as one of the 17 neglected tropical diseases by the World Health Organization. Currently, there are no vaccines available to treat this infection in humans. Therefore, with the objective of devising a novel preventive measure, we exploited an immunoinformatics approa...
Babatope, Tolulope Ilyenkova, Vera Marais, Debbi
Published in
Bulletin of the National Research Centre
Background Since the outbreak of coronavirus (COVID-19) disease was reported in 2019, huge human and material resources have been expended globally to combat the spread of the disease. Achieving herd immunity through mass vaccination remains an important strategy to adopt in the war against this disease since it is practically impossible for 60–70%...
Chakraborty, Prasenjit Kumar, Randhir Karn, Sanjay Srivastava, Ankit Kumar Mondal, Priya
Published in
Bulletin of the National Research Centre
Background When health systems worldwide grapple with the coronavirus disease 2019 (COVID-19) pandemic, its effect on the global environment is also a significant consideration factor. It is a two-way process where the pre-COVID climate factors influenced the landscape in which the disease proliferates globally and the consequences of the pandemic ...
Bokolia, Naveen Prakash Gadepalli, Ravisekhar
Published in
Bulletin of the National Research Centre
Background SARS-CoV-2 is the causative agent of worldwide pandemic disease coronavirus disease 19. SARS-CoV-2 bears positive sense RNA genome that has organized and complex pattern of replication/transcription process including the generation of subgenomic RNAs. Transcription regulatory sequences have important role in the pausing of replication/tr...
Adesola, Ridwan Olamilekan D’Souza, Joanna Nicole Bello, Aisha Bisola Mukwekwe, Varaidzo Joyline
Published in
Bulletin of the National Research Centre
Background and aims In the current global scenario, the monkeypox virus has infected over 3000 individuals from endemic countries like Nigeria, along with non-endemic countries like the UK, Canada, the USA, etc. Based on the current information, it has been observed that monkeypox cases have primarily, though not exclusively, been found among men w...