Published in British journal of cancer
A recent study by Dejea et al. has demonstrated that two enterotoxigenic bacteria frequently associated with sporadic colorectal cancer, Bacteroides fragilis and pks+ Escherichia coli, are found together in biofilms on tissue from patients with familial adenomatous polyposis. In preclinical mouse models, these two bacteria and their corresponding t...
Published in British journal of cancer
Published in British journal of cancer
Published in British journal of cancer
Published in British journal of cancer
Here we identify a nine-gene ECM signature, which strongly predicts outcome across multiple cancer types and can be used for prognostication after validation in prospective cancer cohorts.
Published in British journal of cancer
Published in British journal of cancer
Our data suggest developing dual MTORC1/TORC2 inhibitor-based therapies for subtype-specific intervention.
Published in British journal of cancer
Taken together, we show that BM-MSC can potentially promote the effect of radiotherapy in CRC.
Published in British journal of cancer
Our data suggest that increased expression of HMGA2 represents a possible new mechanism of myeloid differentiation blockage of leukaemia. Aberrant expression of HMGA2 may enhance HOXA9-dependent leukaemogenesis and myeloid leukaemia phenotype. Disturbance of the HMGA2-HOXA9 pathway is probably a therapeutic strategy in myeloid leukaemia.
Published in British journal of cancer
