Taylor, Mallory R Hillard, Cecilia J Drobyski, William R Szabo, Aniko Johnson, Bryon D Zhu, Fenlu Raison, Charles L Cole, Steve W Knight, Jennifer M
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Brain, behavior, & immunity - health
Inflammatory physiology has been linked to behavioral and emotional symptoms in a variety of contexts and experimental paradigms. Hematopoietic cell transplantation (HCT) represents an intersection of significant immune dysregulation and psychosocial stress, and this biobehavioral relationship can influence important clinical outcomes. For those un...
Faraji, Jamshid Bettenson, Dennis Babatunde, Stella Gangur-Powell, Tabitha Yong, Voon Wee Metz, Gerlinde A S
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Brain, behavior, & immunity - health
The course of multiple sclerosis (MS) is characterized by striking sex differences in symptoms such as fatigue and impaired thermal regulation, which are associated with aggravated systemic pro-inflammatory processes. The purpose of this study was to replicate these symptoms in experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice in the ...
Klein, Luise Ophelders, Daan R M G van den Hove, Daniel Damoiseaux, Maurits Rutten, Bart P F Reutelingsperger, Chris P M Schurgers, Leon J Wolfs, Tim G A M
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Brain, behavior, & immunity - health
Systemic and cerebral inflammation following antenatal infection (e.g. chorioamnionitis) and dysregulation of the blood brain barrier (BBB) are major risk factors for abnormal neonatal brain development. Administration of multipotent adult progenitor cells (MAPCs) represents an interesting pharmacological strategy as modulator of the peripheral and...
Chaurasia, Bipin Chavda, Vishal Lu, Bingwei Garg, Kanwaljeet Montemurro, Nicola
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Brain, behavior, & immunity - health
Vaccination is an essential public health strategy to control the 2019 Coronavirus (COVID-19) pandemic. While the benefits of the COVID-19 vaccines far outweigh the risks, side effects continue to be reported in the literature. We report a 65-year-old man who developed cognitive deficits and memory impairments following his first dose of Oxford Ast...
Noss, Melody Moloci Millwood, Summer N Kuhlman, Kate R
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Brain, behavior, & immunity - health
Men and women experience large disparities in prevalence, detection, and clinical course of neurodegenerative diseases. Inflammation has been implicated in the pathogenesis of neurodegenerative diseases, yet there is a paucity of literature documenting sex differences in this phenomenon in prospective, longitudinal studies. Participants were 4217 n...
Hamood, Yesmine Abdullah, Mauda El Ghoul, Hassan Saad, Nazeh Dysko, Robert C Zhang, Zhi
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Brain, behavior, & immunity - health
Children who suffered traumatic brain injury (TBI) often experience acute and chronic pain, which is linked to a poor quality of life. Buprenorphine (BPN) is commonly used to treat moderate to severe persistent pain in children, however, the efficacy and safety profile of BPN in the pediatric population is still inconclusive. This study investigate...
Brown, Lily A Ballentine, Emily Zhu, Yiqin McGinley, Emily L Pezzin, Liliana Abramoff, Benjamin
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Brain, behavior, & immunity - health
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with significant cognitive impairment and increased risk for mental health comorbidities. This study aimed to identify specific associations between cognitive impairment, self-reported disruptions in memory, and psychiatric symptoms including depression, anxiety, p...
Saadat, Nadia Zhang, Liying Hyer, Suzanne Padmanabhan, Vasantha Woo, Jennifer Engeland, Christopher G Misra, Dawn P Giurgescu, Carmen
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Brain, behavior, & immunity - health
African American women are reported to have greater inflammation compared with women from other racial groups. Higher inflammation during pregnancy has been associated with increased risk of adverse perinatal outcomes. We hypothesized that maternal inflammation is related to depressive symptoms and social and behavioral risk factors among pregnant ...
Caldiroli, Alice Capuzzi, Enrico Barkin, Jennifer L Grassi, Silvia Esposito, Cecilia Maria Auxilia, Anna Maria Russo, Stefania Tagliabue, Ilaria Carnevali, Greta Silvia Mucci, Francesco
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Brain, behavior, & immunity - health
The immune and antioxidant systems are intimately connected and their role in the etiology of major psychiatric disorders is currently under study. The aim of this study was to evaluate the potential associations between inflammatory/antioxidant peripheral markers and presence of psychotic symptoms or severity of illness in patients affected by maj...
Finsterer, Josef
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Brain, behavior, & immunity - health