A novel adverse effect of the BNT162b2 mRNA vaccine: First episode of acute mania with psychotic features
Published in Brain, Behavior, & Immunity - Health
Don't forget me in amidst of COVID-19 pandemic: A case series and review of literature on steroid associated psychiatric...
Published in Brain, Behavior, & Immunity - Health
There is a sudden upsurge in the use of steroids due to the ongoing COVID-19 pandemic, especially in patients with severe or critical COVID-19 infection. There are reports of excessive use of steroids, both in terms of use in patients who do not require the same and use in doses higher than the recommended. There are reports of the emergence of dif...
Post-acute sequelae of COVID-19: Evidence of mood & cognitive impairment
Published in Brain, Behavior, & Immunity - Health
• Depressive symptoms were found in the post-acute sequelae of COVID-19 (PASC) sample. • Reward processing and cognitive functioning were impaired in the PASC phase. • PASC was associated with impaired executive function, but not orienting or alerting. • Stress did not moderate PASC effects; between-group pandemic experience was similar. • Protract...
Acute exercise increases immune responses to SARS CoV-2 in a previously infected man
Published in Brain, Behavior, & Immunity - Health
Evidence is emerging that exercise and physical activity provides protection against severe COVID-19 disease in patients infected with SARS-CoV-2, but it is not known how exercise affects immune responses to the virus. A healthy man completed a graded cycling ergometer test prior to and after SARS-CoV-2 infection, then again after receiving an aden...
Psychoneuroimmunology: The new frontier in suicide research
Published in Brain, Behavior, & Immunity - Health
Elucidating complex, multifactorial phenomena like suicide and suicidal behaviors (SSB) require multidisciplinary fields such as Psychoneuroimmunology (PNI). Indeed, our appreciation of the bidirectional communication channels between the brain and the rest of the body with its immune arsenal as the key player has positioned PNI as a promising fiel...
Childhood sexual abuse history amplifies the link between disease burden and inflammation among older adults with HIV
Published in Brain, Behavior, & Immunity - Health
• People living with HIV (PLWH) are at risk for inflammation-related health problems. • Childhood sexual abuse (CSA) may bolster inflammatory pathways in chronic disease. • We tested whether CSA modified links between adult disease burden and inflammation. • Disease burden was more strongly tied to cytokine levels in PLWH with CSA history. • Chroni...
The role of sleep disturbance and inflammation for spatial memory
Published in Brain, Behavior, & Immunity - Health
Spatial memory is a brain function involved in multiple behaviors such as planning a route or recalling an object's location. The formation of spatial memory relies on the homeostasis of various biological systems, including healthy sleep and a well-functioning immune system. While sleep is thought to promote the stabilization and storage of spatia...
Mindfulness interventions for offsetting health risk following early life stress: Promising directions
Published in Brain, Behavior, & Immunity - Health
Early life stress (ELS), common to childhood maltreatment, socioeconomic disadvantage, and racial discrimination, is thought to create a proinflammatory phenotype that increases risk for poor health in adulthood. Systemic change is needed to address the root causes of ELS, but a substantial number of adults are already at increased health risk by v...
Psychoneuroimmunology in the context of perinatal depression - Tools for improved clinical practice
Published in Brain, Behavior, & Immunity - Health
Maternal mental health spans in a temporary manner from pre-conception through the phases of pregnancy, childbirth, and the postpartum period (i.e., perinatal). The psychoneuroimmunology (PNI) field has made important contributions to the knowledge of the pathophysiology of poor perinatal mental health, but the PNI lens could be used more broadly t...
Minocycline in Major Depressive Disorder: And overview with considerations on treatment-resistance and comparisons with ...
Published in Brain, Behavior, & Immunity - Health
Evidence on the link between the immune system and Major Depressive Disorder (MDD) has led to explore antidepressant properties of anti-inflammatory drugs. Among these, minocycline has been identified as a potential novel treatment for MDD, in particular for treatment-resistant depression. The aim of the current paper is to review current pre-clini...
