Ahrweiler, Natasha Santana-Gonzalez, Carmen Zhang, Na Quandt, Grace Ashtiani, Nikki Liu, Guanmin Engstrom, Maggie Schultz, Erika Liengswangwong, Ryan Teoh, Jia Yuan
...
Published in
Brain sciences
Adolescent depression is prevalent, debilitating, and associated with chronic lifetime mental health disorders. Understanding the neurobiology of depression is critical to developing novel treatments. We tested a neurofeedback protocol targeting emotional regulation and self-processing circuitry and examined brain activity associated with reduced s...
Moon, Ja Un Han, Ji Yoon
Published in
Brain sciences
Choosing optimal anti-seizure medication (ASM) is very important in pediatric patients with epilepsy who attend school, especially children with an intellectual disability (ID). Levetiracetam (LEV) has proven to be an effective, safe, generally well-tolerated, broad-spectrum ASM in children. In the context of increasing use of LEV in school-aged ch...
Thomschewski, Aljoscha Trinka, Eugen Jacobs, Julia
Published in
Brain sciences
The prefrontal cortex and hippocampus function in tight coordination during multiple cognitive processes. During spatial navigation, prefrontal neurons are linked to hippocampal theta oscillations, presumably in order to enhance communication. Hippocampal ripples have been suggested to reflect spatial memory processes. Whether prefrontal-hippocampa...
Jiang, Jessica Benhamou, Elia Waters, Sheena Johnson, Jeremy C S Volkmer, Anna Weil, Rimona S Marshall, Charles R Warren, Jason D Hardy, Chris J D
Published in
Brain sciences
The speech we hear every day is typically "degraded" by competing sounds and the idiosyncratic vocal characteristics of individual speakers. While the comprehension of "degraded" speech is normally automatic, it depends on dynamic and adaptive processing across distributed neural networks. This presents the brain with an immense computational chall...
Tak, Yae Won Knights, Ethan Henson, Richard Zeidman, Peter
Published in
Brain sciences
Young people exhibit a negative BOLD response in ipsilateral primary motor cortex (M1) when making unilateral movements, such as button presses. This negative BOLD response becomes more positive as people age. In this study, we investigated why this occurs, in terms of the underlying effective connectivity and haemodynamics. We applied dynamic caus...
Assari, Shervin Boyce, Shanika Akhlaghipour, Golnoush Bazargan, Mohsen Caldwell, Cleopatra H
Published in
Brain sciences
(1) Background: Reward responsiveness (RR) is a risk factor for high-risk behaviors such as aggressive behaviors and early sexual initiation, which are all reported to be higher in African American and low socioeconomic status adolescents. At the same time, parental education is one of the main drivers of reward responsiveness among adolescents. It...
Crooms, Rita C Goldstein, Nathan E Diamond, Eli L Vickrey, Barbara G
Published in
Brain sciences
High-grade glioma (HGG) is characterized by debilitating neurologic symptoms and poor prognosis. Some of the suffering this disease engenders may be ameliorated through palliative care, which improves quality of life for seriously ill patients by optimizing symptom management and psychosocial support, which can be delivered concurrently with cancer...
Cofré, Rodrigo Herzog, Rubén Mediano, Pedro A M Piccinini, Juan Rosas, Fernando E Sanz Perl, Yonatan Tagliazucchi, Enzo
Published in
Brain sciences
The scope of human consciousness includes states departing from what most of us experience as ordinary wakefulness. These altered states of consciousness constitute a prime opportunity to study how global changes in brain activity relate to different varieties of subjective experience. We consider the problem of explaining how global signatures of ...
Steele, Catherine C Gwinner, MacKenzie Smith, Travis Young, Michael E Kirkpatrick, Kimberly
Published in
Brain sciences
Impulsive choice in humans is typically measured using hypothetical delays and rewards. In two experiments, we determined how experiencing the delay and/or the reward affected impulsive choice behavior. Participants chose between two amounts of real or hypothetical candy (M&Ms) after a real or hypothetical delay (5-30 s), where choosing the shorter...
Kim, Jae-Hong Han, Jae-Young Park, Gwang-Cheon Lee, Jeong-Soon
Published in
Brain sciences
This outcome assessor-blinded, randomized controlled clinical trial investigated the effects of electroacupuncture combined with computer-based cognitive rehabilitation (EA-CCR) on mild cognitive impairment (MCI). A per-protocol analysis was employed to compare the efficacy of EA-CCR to that of computer-based cognitive rehabilitation (CCR). Thirty-...
