Huang, Dongying Lv, Caitiao Chen, Zexiang Li, Zhekun Zheng, Jinou
Published in
Brain research
To explore potential mechanisms of cognitive changes in patients with anti-NMDAR encephalitis (ANMDARE) from intramodule and intermodule effects of brain functional networks. Resting-state functional MRI(rs-fMRI) imaging data was collected from 30 ANMDARE and 30 healthy controls (HCs). A brain functional matrix was constructed, and sparsity was est...
Beatriz González-Castro, Thelma Alfonso Tovilla-Zárate, Carlos Esther Juárez-Rojop, Isela Hernández-Díaz, Yazmín Lilia López-Narváez, María Felicita Ortiz-Ojeda, Rosa
Published in
Brain research
Cytokines are among the important effectors and messenger molecules for restoring the homeostasis tissue after an inflammatory response. The association between IL-6 and IL-10 genes polymorphisms with the schizophrenia susceptibility have yielded controversial results. To reconcile the results, a systematic review followed by meta-analysis was perf...
Sun, Yurong Hou, Yingling Wang, Xinyi Wang, Huan Yan, Rui Xue, Li Yao, Zhijian Lu, Qing
Published in
Brain research
Antidepressant treatment effects are strongly heritable and have substantial effects on brain function and structure, but the underlying mechanisms are still poorly understood. In this research, we aimed to evaluate the factors of single nucleotide polymorphisms (SNPs) and hierarchical brain structural and functional networks that were associated w...
Rouzitalab, Alireza Boulay, Chadwick B Sachs, Adam J
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Brain research
Patients diagnosed with Parkinson's disease (PD) have difficulty initiating and executing movements due to an acquired imbalance of the basal ganglia thalamocortical circuit secondary to loss of dopaminergic input into the striatum. The unbalanced circuit is hyper-synchronized, presenting as larger and longer bursts of beta-band (13-30 Hz) oscillat...
Chavan, Ritu S Supalkar, Krishna V Sadar, Smeeta S Vyawahare, Niraj S
Published in
Brain research
Alzheimer's disease (AD) is a progressive neurodegenerative disorder. The main pathogenic features are the development and depositionof senile plaques and neurofibrillary tangles in brain. Recent developments in the knowledge of the pathophysiological mechanisms behind Alzheimer's disease and other cognitive disorders have suggested new approaches ...
Huang, Fankai Huang, Qiankai Zheng, Leyan Zhang, Wenchong Yang, Qi Yang, Jing Wang, Yu Wang, Zhong Li, Weiyun Zeng, Linghui
...
Published in
Brain research
40 Hz light flicker can activate multiple brain regions of wild-type mice. However, there are no systematic studies on the behavioral effects of 40 Hz light flicker on wild-type mice. Adult wild-type C57BL/6J mice were treated with 40 Hz light flicker (200 lx, 40 Hz, 1 h/day for 3 weeks) to evaluate its effects on several behaviors, including mood,...
Speers, Lucinda J Chin, Phoebe Bilkey, David K
Published in
Brain research
Hippocampal phase precession, wherein there is a systematic shift in the phase of neural firing against the underlying theta activity, is proposed to play an important role in the sequencing of information in memory. Previous research shows that the starting phase of precession is more variable in rats following maternal immune activation (MIA), a ...
Kamal, Ahmed Swellam, Menha M Shalaby, Nevin Darwish, Marwa K M El-Nahrery, Eslam
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Brain research
Cognitive impairment is a common and debilitating feature of multiple sclerosis (MS), and the dysregulation of synaptic plasticity is one of its direct causes. Long non-coding RNAs (lncRNAs) have been shown to play a role in synaptic plasticity, but their role in cognitive impairment in MS has not been fully explored. In this study, using quantitat...
Hyldgaard Andersen, Simone Black, Tallan Grassi-Oliveira, Rodrigo Wegener, Gregers
Published in
Brain research
Early-life environmental factors, such as maternal diet or early-life nutrition, have been described as significant risk factors for anxiety and depression later in life. With the rising intake of fructose since the 1960 s, several adverse effects have been described, but little is known about the impact of early-life high fructose exposure on the ...
Kose, Seda Kutlu, Meltem Donmez Kara, Samet Polat, Sait Akillioglu, Kubra
Published in
Brain research
Despite research, the role of exercise in treatment and prevention of neurodegenerative diseases remains unclear. Our study, investigated that protective effect of treadmill exercise on molecular pathways and cognitive behaviours in a scopolamine-induced model of Alzheimer's disease. For that purpose, male Balb/c mice subjected to exercise for 12 w...
