Abd El-Fattah, Amal Ahmed Fahim, Atef Tadros Sadik, Nermin Abdel Hamid Ali, Bassam Mohamed
Published in
Brain research
Chronic stress occurs in everyday life and induces depression. Emerging evidence shows that oxidative stress, inflammation and apoptosis are main contributing pathophysiologic mechanisms of depression. Resveratrol and dimethyl fumarate (DMF) are natural antioxidants that have diverse biological activities. Our study aimed to determine whether resve...
Ahmadi, Shamseddin Alavi, Samaneh Sadat Jadidi, Majid Ardjmand, Abolfazl
Published in
Brain research
The use of mobile phones is increasing, and the main health concern is the possible deleterious effects of radiation on brain functioning. The present study aimed to examine the effects of exposure to a global system for mobile communication (GSM) with mobile phones on inhibitory avoidance (IA) memory performance as well as the involvement of endog...
Mikkelsen, Mark Harris, Ashley D Edden, Richard A E Puts, Nicolaas A J
Published in
Brain research
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) is known to be fundamental to the neuronal processes underlying visual orientation and vibrotactile frequency and amplitude discrimination. Previous studies have demonstrated that performance on visual and vibrotactile psychophysics tasks is associated with in vivo measurements of "GABA+" l...
Wu, Quanyang Zheng, Ruibin Wang, Jiao Wang, Jiaqi Li, Songbai
Published in
Brain research
Cerebral vasospasm may lead to delayed ischemic neurological deficits following subarachnoid hemorrhage (SAH). Endothelin (ET-1) is an important factor participating in cerebral vasospasm underlying SAH. We used a specific endothelin receptor antagonist, BQ123 to assess the specific role of endothelin-1 receptor antagonist in cerebral vasospasm in ...
Baird, Jessica F Hubbard, Elizabeth A Sutton, Bradley P Motl, Robert W
Published in
Brain research
Muscle weakness, particularly in the lower-extremities, is common in multiple sclerosis (MS) and seemingly results from damage along white matter pathways in the central nervous system including the corticospinal tract (CST). This study examined CST structural integrity indicated by diffusion tensor imaging (DTI) related metrics (fractional anisotr...
Li, Yang Jones, Manon Thierry, Guillaume
Published in
Brain research
Linguistic relativity effects arising from differences in terminology and syntax between languages have now been established in various domains of human cognition. Although metaphors have been shown to affect time conceptualisation, there is little evidence to date that the presence or absence of tense within a given language can affect how one pro...
Lanigan, Sinead Corcoran, Alan E Wall, Audrey Mukandala, Gatambwa O'Connor, John J
Published in
Brain research
In the CNS short episodes of acute hypoxia can result in a decrease in synaptic transmission which may be fully reversible upon re-oxygenation. Stabilization of hypoxia-inducible factor (HIF) by inhibition of prolyl hydroxylase domain (PHD) enzymes has been shown to regulate the cellular response to hypoxia and confer neuroprotection both in vivo a...
Ikeda, Hiroko Yonemochi, Naomi Ardianto, Chrismawan Yang, Lizhe Kamei, Junzo
Published in
Brain research
Pregabalin is useful for treating neuropathic pain, but known to increase body weight as a side effect. To investigate the mechanism of this increase in body weight, we focused on dopamine in the lateral hypothalamus (LH) and examined the effects of pregabalin on dopamine levels in the LH and food intake. The dopamine levels in the LH was gradually...
Bamji-Stocke, Sanaya Biggs, Bradley T Samuelsen, Chad L
Published in
Brain research
Eating a new food is a unique event that guides future food choices. A key element for these choices is the perception of flavor (odor-taste associations), a multisensory process dependent upon taste and smell. The two primary cortical areas for taste and smell, gustatory cortex and piriform cortex, are thought to be crucial regions for processing ...
Genna, C. Oddo, C. Fanciullacci, C. Chisari, C. Micera, S. Artoni, F.
Roughness is the most important feature for texture discrimination. Here we investigate how the bilateral cortical representation of touch is modulated by tactile roughness by analyzing the neural responses elicited by stimuli with various coarseness levels ranging from fine to medium. A prolonged stimulation was delivered to 10 healthy subjects by...
